Abstract: The present invention relates to a stable pharmaceutical composition comprising a combination of chlordiazepoxide hydrochloride and clidinium bromide and one or more pharmaceutically acceptable excipients, wherein the composition is in the form of solid oral dosage forms like capsule and sachet. The technical challenges like undesirable impurities in dosage form were successfully controlled by using: a) low moisture excipients; and b) formulation development under controlled temperature and controlled humidity conditions. The formulations as per the present invention are stable and exhibit desired pharmaceutical technical attributes like assay and dissolution. The prepared formulations are useful for the treatment of gastrointestinal disorders and various other therapeutic indications as described herein.

Abstract: The present invention relates to the transmucosal dosage forms like sublingual pharmaceutical compositions comprising antiviral molecules like favipiravir, remdesivir, baloxavir marboxil, molnupiravir, besifovir, raltegravir, GS-441524, ravidasvir, and other antiviral drugs. The present invention also relates to methods for preparing these transmucosal pharmaceutical compositions. Compositions prepared as per the present invention are able to increase bioavailability by avoiding first-pass metabolism. The compositions prepared as per the present invention exhibit desired pharmaceutical technical attributes such as pH, assay, related substance, disintegration, and dissolution. The compositions prepared as per the present invention are useful in the treatment of viral infections including coronavirus infection (COVID-19).

Abstract: The present invention discloses a pallet container cage 100 wherein the horizontal elements 103 and vertical elements 102 of the cage 100 are connected by rivets 101 at uppermost section 109 and lowermost section 110 which pass through the first element and partially through the second element in a way that it grips the second element completely. The first element and the second element are engaged together with the rivet 101. The rivet 101 is inserted from the first element and is passed through the two sections of the first element and partially in the second element which locks with only one section of the second element, more particularly with inner side of the second element. Such system of riveting may enable the exposed surface of the second element to remain smooth and free from any rivet protrusions thereby eliminating the damages caused by the protrusion formed in existing art.

Abstract: Disclosed herein are the sublingual pharmaceutical compositions comprising remdesivir or its pharmaceutically acceptable salts or solvates thereof. The present invention also relates to a process for preparing sublingual pharmaceutical compositions comprising remdesivir or its pharmaceutically acceptable salts or solvates thereof. Compositions of remdesivir prepared as per present invention are able to increase bioavailability by avoiding first-pass metabolism. The compositions of remdesivir prepared as per present invention are useful in the treatment of viral infections including coronavirus infection (COVID-19). The compositions of remdesivir prepared as per present invention exhibit desired pharmaceutical technical attributes such as pH, assay, related substance, disintegration and dissolution.

Abstract: A method and system for preparing softgels. A starch mixture is uniformly heated to an elevated temperature. The starch mixture includes plant starch, plasticizer and water, and does not include carrageenan. The starch mixture is heated to an elevated temperature under mixing for providing liquid starch, maintained at a maintenance temperature under mixing, and then cooled into a pair of starch sheets. Both sheets are provided to a die roller system with at least two pinch surfaces on each die, and sealed together between roller dies as individual softgels are cut by the dies. The die roller system is operated within a die temperature range and at a low die rpm range selected for providing the softgel.

Abstract: Technology is disclosed herein for aborting a tail portion of a command queue in a storage device. In one aspect, one or more control circuits of a storage system are configured to abort tasks at a tail end of a command queue in response to receiving a task tail abort command. However, tasks at the head end of the command queue may still be executed. Thus, the head end of the command queue need not be rebuilt after the task tail abort command is performed. Therefore, considerable time is saved by not having to rebuild the head end of the command queue. Note that the task tail abort command may be received while the storage system is in a sequential command execution mode, in which tasks are executed in the order of their respective task identifiers.

Abstract: Disclosed is a drum stacking assembly 100. The assembly 100 comprises a first set of plurality of drums 108a and a second set of plurality of drums 108b, positioned relative amongst each other via a first connector 101 and a second connector respectively. Further, said assembly 100 comprises a pallet 109, wherein a top surface of the pallet 109 comprises a plurality of support shells 601 further comprising at least a plurality of ribs 602 adapted to support the first set of drums 108a. An outer reinforcing ring of the bottom surface of the first set of drums 108a is guided in the plurality of ribs 602. Further, a bottom surface of the pallet 109 comprises a plurality of grooves 202 further comprising at least a plurality of indentations 603 adapted to engage an outer reinforcing ring 301 of the upper surface of the second set of drums 108b.

Abstract: Technology is disclosed herein for aborting a tail portion of a command queue in a storage device. In one aspect, one or more control circuits of a storage system are configured to abort tasks at a tail end of a command queue in response to receiving a task tail abort command. However, tasks at the head end of the command queue may still be executed. Thus, the head end of the command queue need not be rebuilt after the task tail abort command is performed. Therefore, considerable time is saved by not having to rebuild the head end of the command queue. Note that the task tail abort command may be received while the storage system is in a sequential command execution mode, in which tasks are executed in the order of their respective task identifiers.

Abstract: Disclosed is a polygonal shaped container 101. The polygonal shaped container 101 may comprise a top surface 105 a bottom surface 205 and a plurality of side walls 206. Each edge (201, 203) connecting two side walls of the polygonal shaped container 101 may be filled with additional reinforcement material. The additional reinforcement material along with the polygonal shape of the polygonal-shaped container 101 may facilitate in enhancing compressive strength of the polygonal-shaped container 101. One of the side walls 206 may further comprise a discharge valve 202 fixed entirely within a cavity 204 formed on a lower surface of said one of the side walls 206 such that lowest level of a fluid, contained in the polygonal-shaped container 101, may be discharged from the discharge valve 202. The polygonal-shaped container 101 may be capable of being rolled for portability.

Abstract: Disclosed is a polygonal shaped container 101. The polygonal shaped container 101 may comprise a top surface 105 a bottom surface 205 and a plurality of side walls 206. Each edge (201, 203) connecting two side walls of the polygonal shaped container 101may be filled with additional reinforcement material. The additional reinforcement material along with the polygonal shape of the polygonal-shaped container 101 may facilitate in enhancing compressive strength of the polygonal-shaped container 101. One of the side walls 206 may further comprise a discharge valve 202 fixed entirely within a cavity 204 formed on a lower surface of said one of the side walls 206 such that lowest level of a fluid, contained in the polygonal-shaped container 101, may be discharged from the discharge valve 202. The polygonal-shaped container 101 may be capable of being rolled for portability.

Abstract: Disclosed is a drum stacking assembly 100. The assembly 100 comprises a first set of plurality of drums 108a and a second set of plurality of drums 108b, positioned relative amongst each other via a first connector 101 and a second connector respectively. Further, said assembly 100 comprises a pallet 109, wherein a top surface of the pallet 109 comprises a plurality of support shells 601 further comprising at least a plurality of ribs 602 adapted to support the first set of drums 108a. An outer reinforcing ring of the bottom surface of the first set of drums 108a is guided in the plurality of ribs 602. Further, a bottom surface of the pallet 109 comprises a plurality of grooves 202 further comprising at least a plurality of indentations 603 adapted to engage an outer reinforcing ring 301 of the upper surface of the second set of drums 108b.

Abstract: An end to end system and method for processing and assigning logistic order entered by consignor to a channel partner based on reverse bidding is disclosed. The method may comprise receiving a bid comprising an initial bid amount from each of the one or more channel partner to execute the one or more logistic orders. The method may further comprise assigning an initial score to each of the one or more channel partner based upon the initial bid amount in the bid and a time of bidding by each of the one or more channel partners. The method may further comprise updating the initial bid amount to a revised bid amount in the bid of each of the based upon predefined set of rules.

Abstract: The present invention relates to a connector assembly. The connector assembly includes a connector (101) enabling connection amongst plurality of drums (501), wherein the connector 101 includes a plurality of clamping means (104) at multiple edges of the connector (101), connected to the connector (101) via a plurality of coupling elements (105, 201). A first portion (104a) of each clamping means (104) is coupled with one of the coupling elements (105, 201). The second portion (104b) of each clamping means (104) is adapted to fit within an outer reinforcing ring (504) of a drum to provide a fixed constraint to the plurality of drums (501) placed on a pallet (502). Further, the connector assembly includes a screw-rod fitting (103) having a screw rod (301) extending from the connector (101) and fastened at the pallet (502) positioned below the drums (501) to lock the connector (101) with the pallet (502).

Abstract: In a method for measuring healthcare quality, a plurality of computers operating in parallel receive from a patient dataset representative of patients within a healthcare organization, the patient dataset being distributed across the plurality of computer as subsets of patient datasets. The plurality of computers receive at least one healthcare quality measure definition comprising a numerator and a denominator. The plurality of computers identify, in the subsets of patient datasets, patient data that corresponds to the measure definition. The plurality of computers attribute the identified patient data to at least one provider based on an attribution rule. The plurality of computers calculate at least one healthcare quality measure for the at least one provider, according to the healthcare quality measure definition, based on the attributed patient encounters. The plurality of computers store the at least one calculated healthcare quality measure in a measure dataset.

Abstract: Systems and methods for preparing an application testing environment and for executing an automated test script in an application testing environment are disclosed. According to an aspect, a method includes providing graphical user interface (GUI) test automation objects. The method also includes classifying each of the GUI test automation objects as one of a test essential object and a test navigation object. Further, the method includes serializing the GUI test automation objects classified as a test navigation object for subsequent testing in a testing environment.

Abstract: An apparatus, system, and method that includes a retail container forming an enclosure for retaining a product, a measurement device for calculating an amount of the product removed from the container, an output unit causing a display device to display the removed amount and a total price of the removed amount, a printing device for encoding a representation of the total price onto a label, and a controller for updating an inventory system based on the removed amount.

Abstract: In a method for measuring healthcare quality, a plurality of computers operating in parallel receive from a patient dataset representative of patients within a healthcare organization, the patient dataset being distributed across the plurality of computer as subsets of patient datasets. The plurality of computers receive at least one healthcare quality measure definition comprising a numerator and a denominator. The plurality of computers identify, in the subsets of patient datasets, patient data that corresponds to the measure definition. The plurality of computers attribute the identified patient data to at least one provider based on an attribution rule. The plurality of computers calculate at least one healthcare quality measure for the at least one provider, according to the healthcare quality measure definition, based on the attributed patient encounters. The plurality of computers store the at least one calculated healthcare quality measure in a measure dataset.

Abstract: A system determines the cost of a transaction. The system receives a transaction for an item. The transaction is in terms of a first unit of measure. The system then determines the quantity in terms of a second unit of measure and calculates the cost of the transaction based on the second unit of measure.

Abstract: The invention provides a variable gain amplifier system for use in a burst mode receiver, said system comprising an amplifier adapted to amplify a signal; a gain control module; a dc offset compensation module adapted to derive a compensation signal as a function of the amplifier gain. Compared to existing methods for dc offset compensation in variable gain amplifier, the system and method for dc offset compensation allows fast adjustment of rapidly changing dc offsets that occur in applications where the gain of the variable gain amplifier is adjusted rapidly.

Abstract: A system determines the cost of a transaction. The system receives a transaction for an item. The transaction is in terms of a first unit of measure. The system then determines the quantity in terms of a second unit of measure and calculates the cost of the transaction based on the second unit of measure.