Patents by Inventor Anju Singh

Anju Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NRF2 SMALL MOLECULE INHIBITORS FOR CANCER THERAPY
    Publication number: 20160046616
    Abstract: Small molecule inhibitors of Nrf2 and methods of their use are provided for treating or preventing a disease, disorder or condition associated with an Nrf2-regulated pathway. The compound can be administered as a single agent or can be administered to enhance the efficacy of a chemotherapeutic drug and/or radiation therapy.
    Type: Application
    Filed: March 17, 2014
    Publication date: February 18, 2016
    Applicants: THE JOHNS HOPKINS UNIVERSITY, THE NATIONAL INSTITUTES OF HEALTH, SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
    Inventors: SHYAM S. BISWAL, ANJU SINGH, FRAYDOON RASTINEJAD, MIN SHEN, MATTHEW B. BOXER, YA-QIN ZHANG, JASON M. ROHDE, KYU OH, SREEDHAR VENKANNAGARI
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF DISORDERS RELATING TO OXIDATIVE STRESS
    Publication number: 20150080462
    Abstract: The present invention features methods for treating or preventing conditions, diseases, or disorders related to oxidative stress. In one embodiment, the method increases Nrf2 biological activity or expression. In particular, the invention provides for the treatment or prevention of diseases relating to oxidative stress including emphysema, sepsis, septic shock, ischemic injury, cerebral ischemia and neurodegenerative disorders, meningitis, encephalitis, hemorrhage, cerebral ischemia, heart ischemia, cognitive deficits and neurodegenerative disorders.
    Type: Application
    Filed: August 4, 2014
    Publication date: March 19, 2015
    Inventors: Shyam Biswal, Sylvain Dore, Rajesh Kumar Thimmulappa, Tirumalai Rangasamy, Yoshihito Sakata, Zahoor Ahmad Shah, Hean Zhuang, Anju Singh
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF CHEMORESISTANT NEOPLASIA
    Publication number: 20130309323
    Abstract: The invention generally features compositions and methods useful for the treatment and diagnosis of a neoplasia in a subject. In particular, the invention provides therapeutic compositions that decrease the expression of an Nfr2 nucleic acid molecule or polypeptide for the treatment of a neoplasia, such as a chemoresistant neoplasia, in a subject.
    Type: Application
    Filed: June 14, 2012
    Publication date: November 21, 2013
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Shyam Biswal, Anju Singh
  • Compositions and methods for the treatment or prevention of chemoresistant neoplasia
    Patent number: 8216777
    Abstract: The invention generally features compositions and methods useful for the treatment and diagnosis of a neoplasia in a subject. In particular, the invention provides therapeutic compositions that decrease the expression of an Nfr2 nucleic acid molecule or polypeptide for the treatment of a neoplasia, such as a chemoresistant neoplasia, in a subject.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: July 10, 2012
    Assignee: The Johns Hopkins University
    Inventors: Shyam Biswal, Anju Singh
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
    Publication number: 20100255117
    Abstract: The instant invention provides methods and compositions for the treatment of cancer.
    Type: Application
    Filed: April 6, 2008
    Publication date: October 7, 2010
    Applicant: The Johns Hopkins University
    Inventors: Shyam Biswal, Anju Singh, Deepti Malhotra
  • Compositions and methods for the treatment or prevention of chemoresistant neoplasia
    Publication number: 20100047368
    Abstract: The invention generally features compositions and methods useful for the treatment and diagnosis of a neoplasia in a subject. In particular, the invention provides therapeutic compositions that decrease the expression of an Nfr2 nucleic acid molecule or polypeptide for the treatment of a neoplasia, such as a chemoresistant neoplasia, in a subject.
    Type: Application
    Filed: May 26, 2006
    Publication date: February 25, 2010
    Inventors: Shyam Biswal, Anju Singh