Patents by Inventor Ann McGowan
Ann McGowan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11319283Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: (Formula (I)). Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.Type: GrantFiled: October 4, 2018Date of Patent: May 3, 2022Assignee: MERCK SHARP & DOHME CORP.Inventors: Meredeth Ann McGowan, Abdelghani Achab, Xavier Fradera, Yongxin Han, Derun Li, Jongwon Lim, Kun Liu, Nunzio Sciammetta, Catherine M. White, Wensheng Yu, Hongjun Zhang, Hua Zhou
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Patent number: 11319295Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: (Formula (I)). Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.Type: GrantFiled: October 4, 2018Date of Patent: May 3, 2022Assignee: MERCK SHARP & DOHME CORP.Inventors: Catherine M. White, Meredeth Ann McGowan, Yongxin Han, Nunzio Sciammetta
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Patent number: 11111232Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.Type: GrantFiled: October 4, 2018Date of Patent: September 7, 2021Assignee: Merck Sharp & Dohme Corp.Inventors: Catherine M. White, Abdelghani Achab, Indu T. Bharathan, Xavier Fradera, Yongxin Han, Derun Li, Jongwon Lim, Kun Liu, Meredeth Ann McGowan, Nunzio Sciammetta, Wensheng Yu, Hongjun Zhang, Hua Zhou
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Patent number: 11096930Abstract: Disclosed herein are substituted imidazopyridine compounds of formula (I) which are inhibitors of indoleamine 2,3-dioxygenase (IDO) and/or tryptophan-2,3-dioxygenase (TDO) enzymes: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO- and/or TDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO- and/or TDO-associated disease or disorder.Type: GrantFiled: April 24, 2017Date of Patent: August 24, 2021Assignees: Merck Sharp & Dohme Corp., IOmet Pharma Ltd.Inventors: Phillip M. Cowley, Meredeth Ann McGowan, Thomas J. Brown, Yongxin Han, Kun Liu, Qinglin Pu, Alan Wise, Hongjun Zhang, Hua Zhou
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Publication number: 20200290996Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.Type: ApplicationFiled: October 4, 2018Publication date: September 17, 2020Applicant: MERCK SHARP & DOHME CORP.Inventors: Catherine M. White, Abdelghani Achab, Indu T. Bharathan, Xavier Fradera, Yongxin Han, Derun Li, Jongwon Lim, Kun Liu, Meredeth Ann McGowan, Nunzio Sciammetta, Wensheng Yu, Hongjun Zhang, Hua Zhou
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Publication number: 20200277252Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: (Formula (I)). Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.Type: ApplicationFiled: October 4, 2018Publication date: September 3, 2020Applicant: MERCK SHARP & DOHME CORP.Inventors: Meredeth Ann McGowan, Abdelghani Achab, Xavier Fradera, Yongxin Han, Derun Li, Jongwon Lim, Kun Liu, Nunzio Sciammetta, Catherine M. White, Wensheng Yu, Hongjun Zhang, Hua Zhou
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Publication number: 20200239423Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: (Formula (I)). Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.Type: ApplicationFiled: October 4, 2018Publication date: July 30, 2020Applicant: MERCK SHARP & DOHME CORP.Inventors: Catherine M. White, Meredeth Ann McGowan, Yongxin Han, Nunzio Sciammetta
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Publication number: 20200230117Abstract: Disclosed herein are substituted imidazopyridine compounds of formula (I) which are inhibitors of indoleamine 2,3-dioxygenase (IDO) and/or tryptophan-2,3-dioxygenase (TDO) enzymes: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO- and/or TDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO- and/or TDO-associated disease or disorder.Type: ApplicationFiled: April 24, 2017Publication date: July 23, 2020Applicants: IOMet Pharma Ltd., Merck Sharp & Dohme Corp.Inventors: Phillip M. Cowley, Meredeth Ann McGowan, Thomas J. Brown, Yongxin Han, Kun Liu, Qinglin Pu, Alan Wise, Hongjun Zhang, Hua Zhou
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Patent number: 10538497Abstract: Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.Type: GrantFiled: December 12, 2016Date of Patent: January 21, 2020Assignee: Merck Sharp & Dohme Corp.Inventors: Yongxin Han, Abdelghani Achab, Purakkattle Biju, Yongqi Deng, Xavier Fradera, Liangqin Guo, Shuwen He, Joseph Kozlowski, Ravi Kurukulasuriya, Kun Liu, Meredeth Ann McGowan, Qinglin Pu, Nunzio Sciammetta, Hongjun Zhang, Hua Zhou
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Patent number: 10221178Abstract: The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.Type: GrantFiled: June 24, 2016Date of Patent: March 5, 2019Assignee: Merck Sharp & Dohme Corp.Inventors: Meredeth Ann McGowan, Hua Zhou, Jason D. Katz, Lihu Yang, Joey L. Methot, Kathryn Ann Lipford, Shimin Xu, Ning Fu, Guoquan Xu, Deqian Bian, Jianmin Fu, Yabin Li, Kin Chiu Fong
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Publication number: 20180362482Abstract: Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.Type: ApplicationFiled: December 12, 2016Publication date: December 20, 2018Applicant: Merck Sharp & Dohme Corp.Inventors: Yongxin Han, Abdelghani Achab, Purakkattle Biju, Yongqi Deng, Xavier Fradera, Liangqin Guo, Shuwen He, Joseph Kozlowski, Ravi Kurukulasuriya, Kun Liu, Meredeth Ann McGowan, Qinglin Pu, Nunzio Sciammetta, Hongjun Zhang, Hua Zhou
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Patent number: 10100064Abstract: The instant invention provides compounds of formula (I) which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.Type: GrantFiled: June 9, 2015Date of Patent: October 16, 2018Assignee: MERCK SHARP & DOHME CORP.Inventors: Meredeth Ann McGowan, Kin Chiu Fong, Neville John Anthony, Hua Zhou, Jason D. Katz, Lihu Yang, Chaomin Li, Yuan Tian, Changwei Mu, Baijun Ye, Feng Shi, Xiaoli Zhao, Jianmin Fu, Yabin Li
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Publication number: 20180141947Abstract: The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.Type: ApplicationFiled: June 24, 2016Publication date: May 24, 2018Applicant: MERCK SHARP & DOHME CORP.Inventors: Meredith Ann McGowan, Hua Zhou, Jason D. Katz, Lihu Yang, Joey L. Methot, Kathryn Ann Lipford, Shimin Xu, Ning Fu, Guoquan Xu, Deqian Bian, Jianmin Fu, Yabin Li, Kin Chiu Fong
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Publication number: 20170114078Abstract: The instant invention provides compounds of formula (I) which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.Type: ApplicationFiled: June 9, 2015Publication date: April 27, 2017Applicant: Merck Sharp Dohme Corp.Inventors: Meredeth Ann McGowan, Kin Chiu Fong, Neville John Anthony, Hua Zhou, Jason D. Katz, Lihu Yang, Chaomin Li, Yuan Tian, Changwei Mu, Baijun Ye, Feng Shi, Xiaoli Zhao, Jianmin Fu, Yabin Li
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Publication number: 20050240963Abstract: An interactive gateway creates a centralized location that allows subscribers and non-subscribers to premium television channels to navigate interactive television features and added value content for the programming services available on the subscription channels. The programming services available on the subscription channels may include movies, original series, boxing and family programming. The interactive gateway can also introduce subscribers and non-subscribers to all of the channels and interactive services available from a particular content provider. Although both subscriber and non-subscribers can access the interactive gateway, their experiences may be different. Different content is preferably provided based on a viewer's subscription status. Non-subscribers are presented with promotion material regarding the programming services to entice non-subscribers to become subscribers.Type: ApplicationFiled: April 21, 2004Publication date: October 27, 2005Applicant: Showtime Networks, Inc.Inventors: David Preisman, Ann McGowan, Julia Veale, Christopher Lucas
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Publication number: 20050060748Abstract: An exemplary embodiment of the present invention is directed to a system, method, and computer program product for electronically upgrading a user content subscription for programming services. In an exemplary embodiment, the method can include the steps of: (a) identifying at least one content distributor available to a user; (b) identifying a price to the user for a programming service from the at least one content distributor; (c) presenting an offer for the programming service to the user for the price; (d) receiving an acceptance of the offer for the programming service for the price; and (e) activating the programming service.Type: ApplicationFiled: March 18, 2004Publication date: March 17, 2005Applicant: Showtime Networks Inc.Inventors: Jordan Berman, Justin Edelson, Ann McGowan, Kevin Parks, James Occhiuto, David Preisman