Abstract: The invention relates to compounds of general formula (I): wherein R2a, R2b, R3a, R3b, R5, Y and R7 are as defined herein are selective agonists at the FXR receptor and are useful for the treatment or prevention of diseases and conditions including nonalcoholic steatohepatitis (NASH); primary biliary cirrhosis; primary sclerosing cholangitis; biliary atresia; cholestatic liver disease; hepatitis C infection; alcoholic liver disease; fibrosis; and liver damage arising from fibrosis.

Abstract: The present invention concerns a foamable polymer composition and a foamed polymer composition obtained by foaming this foamable polymer composition. The invention is also concerned with a cable comprising at least one layer which comprises the foamable polymer composition or the foamed polymer composition. The invention further provides a process for producing a foamed polymer composition.

Abstract: The invention relates to a foamable polymer composition comprising a blowing agent and a foamed polymer composition obtained by foaming this foamable polymer composition. The invention further relates to a cable comprising at least one layer which comprises the foamable polymer composition or a foamed polymer composition.

Abstract: The present invention is directed to a new cable having at least one insulation layer, to a process for producing such cable as well as to the use of a polymeric-nucleating agent for increasing the crystallization temperature of a polymer composition being part of an insulation layer of such a cable and the use of such a cable as communication cable and/or electrical cable.

Abstract: The invention relates to compounds of general formula (I): wherein R2a, R2b, R3a, R3b, R5, Y and R7 are as defined herein are selective agonists at the FXR receptor and are useful for the treatment or prevention of diseases and conditions including nonalcoholic steatohepatitis (NASH); primary biliary cirrhosis; primary sclerosing cholangitis; biliary atresia; cholestatic liver disease; hepatitis C infection; alcoholic liver disease; fibrosis; and liver damage arising from fibrosis.

Abstract: The present invention is directed to a new cable having at least one insulation layer, to a process for producing such cable as well as to the use of a soluble a-nucleating agent (NA) for increasing the crystallization temperature of a polymer composition (PC) being part of an insulation layer of such a cable and the use of such a cable as communication cable and/or electrical cable.

Abstract: The present invention relates to a compounded polyethylene composition having a density of 930 to 965 kg/m3 and comprising at least 0.01 percent by weight (wt-%) of sodium bicarbonate after compounding of the compounded polyethylene composition, wherein the ratio between sodium bicarbonate, in the polyethylene composition, before and after compounding is X, wherein X1?X<X2, and X1 is 1.00 and X2 is 2.00, an article, for example, a coating, a wire or a cable, comprising the compounded polyethylene composition, a process for producing the article, and use of the compounded polyethylene composition.

Abstract: The invention relates to a tube comprising a heterophasic polypropylene composition comprising a heterophasic polypropylene copolymer with an antioxidant comprising a sterically hindered phenol. The heterophasic polypropylene copolymer has the relative amount of crystal line polypropylene above 20 wt %. the relative amount of xylene cold solubles (XCS) fraction is at least 10 wt % and the relative content of isolated ethylene sequences (I(E)) of the XCS fulfills the equation: I(E)<78?1.97×C+0.015×(C)2 wherein C is the comonomer content [wt %] of the XCS fraction and wherein the I(E) content is defined by equation I(E) wherein I(E) is the relative content of isolated to block ethylene sequences.

Abstract: The invention relates to a cable comprising at least one layer which comprises a foamable polyolefin polymer composition comprising a polyolefin polymer composition and blowing agent wherein the blowing agent comprises more than 90 wt % of citric acid or a derivate of citric acid.

Abstract: The invention relates to a tube comprising a heterophasic polypropylene composition comprising a heterophasic polypropylene copolymer with an antioxidant comprising a sterically hindered phenol. The heterophasic polypropylene copolymer has the relative amount of crystal line polypropylene above 20 wt %. the relative amount of xylene cold solubles (XCS) fraction is at least 10 wt % and the relative content of isolated ethylene sequences (I(E)) of the XCS fulfills the equation: I(E)<78?1.97×C+0.015×(C)2 wherein C is the comonomer content [wt %] of the XCS fraction and wherein the I(E) content is defined by equation I(E) wherein I(E) is the relative content of isolated to block ethylene sequences.

Abstract: A semiconductive polyolefin composition comprising (i) up to 80 wt. % of a polyolefin (I), (ii) carbon black, and (iii) up to 60 wt. % of a polymer (II) having a melting point of not less than 100° C., wherein the polyolefin (I) comprises two different ethylene copolymers: a first ethylene copolymer and second ethylene copolymer; wherein the first ethylene copolymer comprises polar group containing co-monomers in the amount of 3.5 mol % or less; and wherein the second ethylene copolymer comprises silane group containing co-monomers in the amount of 0.7 mol % or less.

Abstract: Aspects retrieve, organize and display different classifications of sets of search results in different, respective tabbed sheets that are nested on top of one another in a web-based interface dashboard. A text string search query is classified into constituent primary search terms that are likely to return satisfactory search results as indicated by retrieved search history data as a function of search resources and language classification rules associated with the user identity indicia. Secondary search terms related to the primary search terms and including synonyms and antonyms are determined as substitutes for the primary search terms in response to search history indicating follow-up searches immediately subsequent to searches of the primary search terms at less than a specified threshold of frequency. The set of peripheral knowledge article results is generated by searching knowledge article resources for background information on the primary search terms or the secondary search terms.

Abstract: Aspects retrieve, organize and display different classifications of sets of search results in different, respective tabbed sheets that are nested on top of one another in a web-based interface dashboard. A text string search query is classified into constituent primary search terms that are likely to return satisfactory search results as indicated by retrieved search history data as a function of search resources and language classification rules associated with the user identity indicia. Secondary search terms related to the primary search terms and including synonyms and antonyms are determined as substitutes for the primary search terms in response to search history indicating follow-up searches immediately subsequent to searches of the primary search terms at less than a specified threshold of frequency. The set of peripheral knowledge article results is generated by searching knowledge article resources for background information on the primary search terms or the secondary search terms.

Abstract: The present invention is directed to a new cable having at least one insulation layer, to a process for producing such cable as well as to the use of a polymeric-nucleating agent for increasing the crystallization temperature of a polymer composition being part of an insulation layer of such a cable and the use of such a cable as communication cable and/or electrical cable.

Abstract: A semiconductive polyolefin composition comprising (i) up to 80 wt. % of a polyolefin (I), (ii) carbon black, and (iii) up to 60 wt. % of a polymer (II) having a melting point of not less than 100° C., wherein the polyolefin (I) comprises two different ethylene copolymers: a first ethylene copolymer and second ethylene copolymer; wherein the first ethylene copolymer comprises polar group containing co-monomers in the amount of 3.5 mol % or less; and wherein the second ethylene copolymer comprises silane group containing co-monomers in the amount of 0.7 mol % or less.

Abstract: The present invention relates to a semiconductive polyolefin composition comprising: (i) up to 80 wt. % of a polyolefin (I), (ii) carbon black, and (iii) optionally up to 60 wt. % of a polymer (II) having a melting point of not less than 100° C., wherein the polyolefin (I) has a co-monomer content of equal to or less than 4.3 mol %, to the use of that composition for the production of a power cable and to a power cable comprising that composition.

Abstract: The present invention is directed to a new cable having at least one insulation layer, to a process for producing such cable as well as to the use of a soluble a-nucleating agent (NA) for increasing the crystallization temperature of a polymer composition (PC) being part of an insulation layer of such a cable and the use of such a cable as communication cable and/or electrical cable.

Abstract: Isolated immunomodulatory (e.g. immunostimulatory) polyhydroxlated pyrrolizidine compounds having the formula (I), wherein R is selected from the group comprising hydrogen, straight or branched, unsubstituted or substituted, saturated or unsaturated acyl, alkyl (e.g. cycloalkyl), alkenyl, alkynyl and aryl groups, or a pharmaceutically acceptable salt or derivative thereof, are useful in therapy and prophylaxis, including increasing the Th1:Th2 response ratio, haemorestoration, alleviation of immuno-suppression, cytokine stimulation, treatment of proliferative disorders (e.g. cancer), vaccination, stimulation of the innate immune response and boosting of the activity of endogenous NK cells.

Abstract: Isolated immunomodulatory (e.g. immunostimulatory) polyhydroxlated pyrrolizidine compounds having the formula are disclosed. In these compounds R is selected from hydrogen, straight or branched, unsubstituted or substituted, saturated or unsaturated acyl, alkyl (e.g. cycloalkyl), alkenyl, alkynyl and aryl groups. The compounds are useful in therapy and prophylaxis, including increasing the Th1:Th2 response ratio, hemorestoration, alleviation of immunosuppression, cytokine stimulation, treatment of proliferative disorders (e.g. cancer), vaccination, stimulation of the innate immune response and boosting of the activity of endogenous NK cells.

Abstract: The present invention relates to a semiconductive polyolefin composition comprising: (i) up to 80 wt. % of a polyolefin (I), (ii) carbon black, and (iii) optionally up to 60 wt. % of a polymer (II) having a melting point of not less than 100° C., wherein the polyolefin (I) has a co-monomer content of equal to or less than 4.3 mol %, to the use of that composition for the production of a power cable and to a power cable comprising that composition.