Abstract: The present application relates to the administration of plasma, fractions thereof, or mixtures thereof to humans or animals to treat or otherwise improve cognitive impairment disorders, including dementia (e.g., vascular dementia, dementia with Lewy bodies, dementia resulting from Alzheimer's disease, dementia resulting from Parkinson's disease, frontotemporal dementia, and dementia resulting from normal pressure hydrocephalus in humans, and cognitive dysfunction syndrome in companion animals), concussion, and traumatic brain injury.

Abstract: The present invention relates to a blister pack that comprises a base laminate with a sealing layer and a lid laminate with a sealing layer, the base laminate having at least one cavity housing a product. The base laminate and the lid laminate are directly sealed to each other via their identical sealing layers whereby the seal comprises two different sealing subzones, a first sealing subzone providing a permanent seal and a second sealing subzone providing a peelable seal.

Abstract: The present application relates to the administration of plasma, fractions thereof, or mixtures thereof to humans or animals to treat or otherwise improve cognitive impairment disorders, including dementia (e.g.

Abstract: The present invention relates to a blister pack that comprises a base laminate with a sealing layer and a lid laminate with a sealing layer, the base laminate having at least one cavity housing a product. The base laminate and the lid laminate are directly sealed to each other via their identical sealing layers whereby the seal comprises two different sealing subzones, a first sealing subzone providing a permanent seal and a second sealing subzone providing a peelable seal.

Abstract: The present invention discloses a packaging pouch for a viscous content, the pouch comprising a flexible multilayer laminate, said laminate comprising an inner layer in contact, in use, with the content of said pouch, the pouch comprising a top region and a bottom region and one or more cross-seal(s), said pouch comprising a tearable venting means in the bottom region.

Abstract: The present invention discloses a packaging pouch for a viscous content, the pouch comprising a flexible multilayer laminate, said laminate comprising an inner layer in contact, in use, with the content of said pouch, the pouch comprising a top region and a bottom region and one or more cross-seal(s), said pouch comprising a tearable venting means in the bottom region.

Abstract: The present invention provides methods for reducing, attenuating, diminishing, preventing or inhibiting pulmonary inflammation in an animal by orally administering a plasma fraction comprising at least 30% by weight IgG and 10% or less by weight IgA to said animal prior to or following exposure or challenge of the animal to an endotoxin.

Abstract: The present invention is related to a peelable film to be sealed on a polyester-based substrate comprising a coextraded multilayer structure comprising:—a rupturable polyester-based sealant layer;—an adhesive layer in contact with said rupturable layer, comprising a polymer selected from the group consisting of ionomers, maleic anhydride grafted polyolefin, EVA, EBA, EMA and EAA;—a gas-barrier layer in contact with said adhesive layer, comprising a gas-barrier polymer selected from the group consisting of EVOH and polyamide, characterised in that the average peel strength between the adhesive layer and the rupturable sealant layer is lower than 15 N/15 mm, preferably lower than 13 N/15 mm as measured in a 180° peel geometry.

Abstract: The present invention provides methods for reducing, attenuating, diminishing, preventing or inhibiting pulmonary inflammation in an animal by orally administering a plasma fraction to said animal prior to or following exposure or challenge of the animal to an endotoxin.