Patents by Inventor Anne Lermet

Anne Lermet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective protein kinase inhibitors
    Patent number: 9168245
    Abstract: The present invention relates to compounds of formula I or pharmaceutically acceptable salts thereof: wherein R1, R2, R3, A, Q, W and X are as defined in the description. These compounds selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant protein kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective native and/or mutant c-kit inhibitors.
    Type: Grant
    Filed: July 24, 2012
    Date of Patent: October 27, 2015
    Assignee: AB SCIENCE
    Inventors: Abdellah Benjahad, Alain Moussy, Emmanuel Chevenier, Willy Picoul, Anne Lermet, Didier Pez, Jason Martin, Franck Sandrinelli
  • Aminothiazole compounds as kinase inhibitors and methods of using the same
    Patent number: 8940894
    Abstract: The present invention relates to an industrial process of preparing pharmaceutical compounds having the formula I: which are useful as certain tyrosine kinase inhibitors and more particularly as c-kit and bcr-abl inhibitors. The groups R1 and R2, identical or different, represent each a hydrogen, halogen atom, an alkyl, an alkoxy, a trifluoromethyl, an amino, an alkylamino, a dialkylamino, a solubilising group; m is 0-5 and n is 0-4; the group R3 represents an aryl or an heteroaryl group as described in claims herein.
    Type: Grant
    Filed: May 10, 2013
    Date of Patent: January 27, 2015
    Assignee: AB Science
    Inventors: Alain Moussy, Philippe Reginault, Francois Bellamy, Anne Lermet
  • SELECTIVE PROTEIN KINASE INHIBITORS
    Publication number: 20140179698
    Abstract: The present invention relates to compounds of formula I or pharmaceutically acceptable salts thereof: wherein R1, R2, R3, A, Q, W and X are as defined in the description. These compounds selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant protein kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective native and/or mutant c-kit inhibitors.
    Type: Application
    Filed: July 24, 2012
    Publication date: June 26, 2014
    Applicant: AB SCIENCE
    Inventors: Abdellah Benjahad, Alain Moussy, Emmanuel Chevenier, Willy Picoul, Anne Lermet, Didier Pez, Jason Martin, Franck Sandrinelli
  • Aminothiazole compounds as kinase inhibitors and methods of using the same
    Patent number: 8492545
    Abstract: The present invention relates to an industrial process of preparing pharmaceutical compounds having the formula I: which are useful as certain tyrosine kinase inhibitors and more particularly as c-kit and bcr-abl inhibitors. The groups R1 and R2, identical or different, represent each a hydrogen, halogen atom, an alkyl, an alkoxy, a trifluoromethyl, an amino, an alkylamino, a dialkylamino, a solubilising group; m is 0-5 and n is 0-4; the group R3 represents an aryl or an heteroaryl group as described in claims herein.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: July 23, 2013
    Assignee: AB Science
    Inventors: Alain Moussy, Philippe Reginault, Francois Bellamy, Anne Lermet
  • PROCESS FOR THE SYNTHESIS OF 2-AMINOTHIAZOLE COMPOUNDS AS KINASE INHIBITORS
    Publication number: 20120196871
    Abstract: The present invention relates to an industrial process of preparing pharmaceutical compounds having the formula I: which are useful as certain tyrosine kinase inhibitors and more particularly as c-kit and bcr-abl inhibitors. The groups R1 and R2, identical or different, represent each a hydrogen, halogen atom, an alkyl, an alkoxy, a trifluoromethyl, an amino, an alkylamino, a dialkylamino, a solubilising group; m is 0-5 and n is 0-4; the group R3 represents an aryl or an heteroaryl group as described in claims herein.
    Type: Application
    Filed: March 8, 2012
    Publication date: August 2, 2012
    Applicant: AB SCIENCE
    Inventors: Alain MOUSSY, Philippe REGINAULT, François BELLAMY, Anne LERMET
  • Process for the synthesis of 2-aminothiazole compounds as kinase inhibitors
    Patent number: 8153792
    Abstract: The present invention relates to an industrial process of preparing pharmaceutical compounds having the formula (1) which are useful as certain tyrosine kinase inhibitors and more particularly as c-kit and bcr-abl inhibitors. The groups R1 and R2, identical or different, represent each a hydrogen, halogen atom, an alkyl, an alkoxy, a trifluoromethyl, an amino, an alkylamino, a dialkylamino, a solubilising group; m is 0-5 and n is 0-4; the group R3 represents an aryl or an heteroaryl group as described in claims herein.
    Type: Grant
    Filed: February 13, 2008
    Date of Patent: April 10, 2012
    Assignee: AB Science
    Inventors: Alain Moussy, Philippe Reginault, François Bellamy, Anne Lermet
  • PROCESS FOR THE SYNTHESIS OF 2-AMINOTHIAZOLE COMPOUNDS AS KINASE INHIBITORS
    Publication number: 20100121063
    Abstract: The present invention relates to an industrial process of preparing pharmaceutical compounds having the formula (1) which are useful as certain tyrosine kinase inhibitors and more particularly as c-kit and bcr-abl inhibitors. The groups R1 and R2, identical or different, represent each a hydrogen, halogen atom, an alkyl, an alkoxy, a trifluoromethyl, an amino, an alkylamino, a dialkylamino, a solubilising group; m is 0-5 and n is 0-4; the group R3 represents an aryl or an heteroaryl group as described in claims herein.
    Type: Application
    Filed: February 13, 2008
    Publication date: May 13, 2010
    Applicant: AB SCIENCE
    Inventors: Alain Moussy, Philippe Reginault, Francois Bellamy, Anne Lermet