Patents by Inventor Annette Bistrup

Annette Bistrup has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ECM-Complex Antibody Compositions and Methods of Use
    Publication number: 20100074893
    Abstract: The invention provides isolated anti-ECM-complex antibodies that bind to ECM-complexes. The invention also encompasses compositions comprising an anti-ECM-complex antibody and a carrier. These compositions can be provided in an article of manufacture or a kit. Another aspect of the invention is an isolated nucleic acid encoding an anti-ECM-complex antibody, as well as an expression vector comprising the isolated nucleic acid. Also provided are cells that produce the anti-ECM-complex antibodies. The invention encompasses a method of producing the anti-ECM-complex antibodies. Other aspects of the invention are a method of detecting an ECM-complex expressing cancer, a method of inhibiting growth of an ECM-complex-expressing tumor, and a method of alleviating or treating an ECM-complex-expressing cancer in a mammal, comprising administering a therapeutically effective amount of the anti-ECM-complex antibody to the mammal.
    Type: Application
    Filed: April 10, 2009
    Publication date: March 25, 2010
    Inventors: Annette Bistrup, Gundo Diedrich, Paul Levi Miller
  • Glycosyl sulfotransferase-3
    Patent number: 6967093
    Abstract: A novel human glycosylsulfotransferase expressed in high endothelial cells (GST-3) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting selectin mediated binding events and methods of treating disease conditions associated therewith.
    Type: Grant
    Filed: March 22, 2001
    Date of Patent: November 22, 2005
    Assignees: The Regents of the University of California, Syntex (U.S.A) LLC
    Inventors: Annette Bistrup, Steven D. Rosen, Stefan Hemmerich
  • HEC-G1CNAC6ST
    Patent number: 6933142
    Abstract: Mammalian glycosylsulfotransferases expressed in high endothelial cells (HEC-GLCNAC6ST) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting selectin mediated binding events and methods of treating disease conditions associated therewith, particularly by administering an inhibitor of at least one of HEC-GLCNAC6ST or KSGal6ST, or homologues thereof.
    Type: Grant
    Filed: August 23, 2000
    Date of Patent: August 23, 2005
    Assignees: The Regents of the University of California, Syntex (USA), LLC
    Inventors: Annette Bistrup, Steven D. Rosen, Stefan Hemmerich
  • Methods of inhibition using glycosyl sulfotransferase-3
    Patent number: 6844175
    Abstract: A novel human glycosylsulfotransferase expressed in high endothelial cells (GST-3) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: January 18, 2005
    Assignees: The Regents of the University of the California, Syntex (U.S.A.) INC
    Inventors: Annette Bistrup, Steven D. Rosen, Kirsten Tangemann, Stefan Hemmerich
  • Glycosyl sulfotransferase-3
    Publication number: 20020164748
    Abstract: A novel human glycosylsulfotransferase expressed in high endothelial cells (GST-3) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting selectin mediated binding events and methods of treating disease conditions associated therewith, particularly by administering an inhibitor of at least one of GST-3 or KSGal6ST, or homologues thereof.
    Type: Application
    Filed: November 8, 2001
    Publication date: November 7, 2002
    Inventors: Annette Bistrup, Steven D. Rosen, Kirsten Tangemann, Stefan Hemmerich
  • Method of determining whether an agent modulates glycosyl sulfotransferase-3
    Patent number: 6365365
    Abstract: A novel human glycosylsulfotransferase expressed in high endothelial cells (GST-3) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting selectin mediated binding events and methods of treating disease conditions associated therewith, particularly by administering an inhibitor of at least one of GST-3 or KSGal6ST, or homologues thereof.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: April 2, 2002
    Assignee: The Regents of the University of California
    Inventors: Annette Bistrup, Steven D. Rosen, Kirsten Tangemann, Stefan Hemmerich
  • Glycosyl sulfotransferase-3
    Publication number: 20010051370
    Abstract: A novel human glycosylsulfotransferase expressed in high endothelial cells (GST-3) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting selectin mediated binding events and methods of treating disease conditions associated therewith.
    Type: Application
    Filed: March 22, 2001
    Publication date: December 13, 2001
    Inventors: Annette Bistrup, Steven D. Rosen, Stefan Hemmerich
  • Glycosly sulfortransferase-3
    Patent number: 6265192
    Abstract: A novel human glycosylsulfotransferase expressed in high endothelial cells (GST-3) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting selectin mediated binding events and methods of treating disease conditions associated therewith.
    Type: Grant
    Filed: March 20, 1998
    Date of Patent: July 24, 2001
    Assignees: The Regents of the University of California, Syntex, Inc.,
    Inventors: Annette Bistrup, Steven D. Rosen, Stefan Hemmerich