Patents by Inventor Annette Shadiack

Annette Shadiack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230277555
    Abstract: This disclosure provides pharmaceutical compositions for delivering estradiol to a subject in need thereof, as well as methods of administering the compositions, and methods of using them.
    Type: Application
    Filed: March 1, 2023
    Publication date: September 7, 2023
    Inventors: Veeran Gowda KADAJJI, Mafruhul BARI, Annette SHADIACK, Thorsteinn THORSTEINSSON, Peter H.R. PERSICANER
  • Patent number: 11633405
    Abstract: This disclosure provides pharmaceutical compositions for delivering estradiol to a subject in need thereof, as well as methods of administering the compositions, and methods of using them.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: April 25, 2023
    Assignee: TherapeuticsMD, Inc.
    Inventors: Veeran Gowda Kadajji, Mafruhul Bari, Annette Shadiack, Thorsteinn Thorsteinsson, Peter H. R. Persicaner
  • Publication number: 20210244747
    Abstract: This disclosure provides pharmaceutical compositions for delivering estradiol to a subject in need thereof, as well as methods of administering the compositions, and methods of using them.
    Type: Application
    Filed: February 5, 2021
    Publication date: August 12, 2021
    Inventors: Veeran Giwda KADAJJI, Mafruhul BARI, Annette Shadiack, Thorsteinn THORSTEINSSON, Peter H.R. PERSICANER
  • Patent number: 10532059
    Abstract: This disclosure provides a novel pharmaceutical composition for delivering steroid hormones to a patient in need thereof.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: January 14, 2020
    Assignee: TherapeuticsMD, Inc.
    Inventors: Annette Shadiack, Peter H. R. Persicaner, Philip B. Inskeep, Thorsteinn Thorsteinsson, Frederick D. Sancilio, Jason D. Legassie
  • Patent number: 10471074
    Abstract: This disclosure provides a novel pharmaceutical composition for delivering steroid hormones to a patient in need thereof.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: November 12, 2019
    Assignee: TherapeuticsMD, Inc.
    Inventors: Annette Shadiack, Peter H. R. Persicaner, Philip B. Inskeep, Thorsteinn Thorsteinsson, Frederick D. Sancilio, Jason D. Legassie
  • Publication number: 20190282698
    Abstract: This disclosure provides a novel pharmaceutical composition capable of forming micelles upon exposure to the gastric environment. The pharmaceutical composition is suitable for delivering steroid hormones, and progesterone in particular, to a subject in need thereof.
    Type: Application
    Filed: March 20, 2019
    Publication date: September 19, 2019
    Inventors: Annette SHADIACK, Peter H.R. PERSICANER, Philip B. INSKEEP, Thorsteinn THORSTEINSSON, Frederick D. SANCILIO, Jason D. LEGASSIE
  • Patent number: 10286077
    Abstract: This disclosure provides a novel pharmaceutical composition capable of forming micelles upon exposure to the gastric environment. The pharmaceutical composition is suitable for delivering steroid hormones, and progesterone in particular, to a subject in need thereof.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: May 14, 2019
    Assignee: TherapeuticsMD, Inc.
    Inventors: Annette Shadiack, Peter H. R. Persicaner, Philip B. Inskeep, Thorsteinn Thorsteinsson, Frederick D. Sancilio, Jason D. Legassie
  • Publication number: 20190070197
    Abstract: This disclosure relates to transdermal pharmaceutical compositions containing progesterone in combination with one or more solubilizing agents and penetration enhancers, wherein the pharmaceutical compositions are formulated as creams for topical administration. In some embodiments, the transdermal pharmaceutical compositions contain progesterone, a medium-chain oil, and d-limonene. In some embodiments, the transdermal pharmaceutical compositions contain progesterone, a medium-chain oil, a penetration enhancer (e.g., propylene glycol, a fatty acid ester of propylene glycol, a glycol ether), and optionally d-limonene. In certain embodiments, the pharmaceutical compositions further include estradiol. Methods for treating conditions associated with hormone deficiency in a subject are also described.
    Type: Application
    Filed: September 7, 2018
    Publication date: March 7, 2019
    Inventors: JULIA AMADIO, ANNETTE SHADIACK, PETER H.R. PERSICANER, RICHARD WINNEKER, JASON LEGASSIE, THORSTEINN THORSTEINSSON, AJAY GHANTA
  • Patent number: 10098894
    Abstract: This disclosure relates to transdermal pharmaceutical compositions containing progesterone in combination with one or more solubilizing agents and penetration enhancers, wherein the pharmaceutical compositions are formulated as creams for topical administration. In some embodiments, the transdermal pharmaceutical compositions contain progesterone, a medium-chain oil, and d-limonene. In some embodiments, the transdermal pharmaceutical compositions contain progesterone, a medium-chain oil, a penetration enhancer (e.g., propylene glycol, a fatty acid ester of propylene glycol, a glycol ether), and optionally d-limonene. In certain embodiments, the pharmaceutical compositions further include estradiol. Methods for treating conditions associated with hormone deficiency in a subject are also described.
    Type: Grant
    Filed: July 29, 2015
    Date of Patent: October 16, 2018
    Assignee: TherapeuticsMD, Inc.
    Inventors: Julia Amadio, Annette Shadiack, Peter H. R. Persicaner, Richard Winneker, Jason Legassie, Thorsteinn Thorsteinsson, Ajay Ghanta
  • Publication number: 20180280411
    Abstract: This disclosure provides a novel pharmaceutical composition for delivering steroid hormones to a patient in need thereof.
    Type: Application
    Filed: February 21, 2018
    Publication date: October 4, 2018
    Inventors: Annette SHADIACK, Peter H.R. PERSICANER, Philip B. INSKEEP, Thorsteinn THORSTEINSSON, Frederick D. SANCILIO, Jason D. LEGASSIE
  • Patent number: 9931349
    Abstract: This disclosure provides a novel pharmaceutical composition for delivering steroid hormones to a patient in need thereof.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: April 3, 2018
    Assignee: TherapeuticsMD, Inc.
    Inventors: Annette Shadiack, Peter H. R. Persicaner, Philip B. Inskeep, Thorsteinn Thorsteinsson, Frederick D. Sancilio, Jason D. Legassie
  • Publication number: 20170281776
    Abstract: This disclosure provides a novel pharmaceutical composition capable of forming micelles upon exposure to the gastric environment.
    Type: Application
    Filed: March 30, 2017
    Publication date: October 5, 2017
    Inventors: Annette SHADIACK, Peter H.R. PERSICANER, Philip B. INSKEEP, Thorsteinn THORSTEINSSON, Frederick D. SANCILIO, Jason D. LEGASSIE
  • Publication number: 20170281645
    Abstract: This disclosure provides a novel pharmaceutical composition for delivering steroid hormones to a patient in need thereof.
    Type: Application
    Filed: March 30, 2017
    Publication date: October 5, 2017
    Inventors: Annette SHADIACK, Peter H.R. PERSICANER, Philip B. INSKEEP, Thorsteinn THORSTEINSSON, Frederick D. SANCILIO, Jason D. LEGASSIE
  • Publication number: 20170281647
    Abstract: This disclosure provides a novel pharmaceutical composition capable of forming micelles upon exposure to the gastric environment. The pharmaceutical composition is suitable for delivering steroid hormones, and the combination of estradiol and progesterone in particular, to a subject in need thereof.
    Type: Application
    Filed: March 30, 2017
    Publication date: October 5, 2017
    Inventors: ANNETTE SHADIACK, PETER H.R. PERSICANER, PHILIP B. INSKEEP, THORSTEINN THORSTEINSSON, FREDERICK D. SANCILIO, JASON D. LEGASSIE
  • Publication number: 20170281646
    Abstract: This disclosure provides a novel pharmaceutical composition for delivering steroid hormones, such as estradiol and progesterone, to a patient in need thereof.
    Type: Application
    Filed: March 30, 2017
    Publication date: October 5, 2017
    Inventors: PHILIP B. INSKEEP, PETER H.R. PERSICANER, ANNETTE SHADIACK, THORSTEINN THORSTEINSSON, FREDERICK D. SANCILIO, JASON D. LEGASSIE
  • Publication number: 20160030449
    Abstract: This disclosure relates to transdermal pharmaceutical compositions containing progesterone in combination with one or more solubilizing agents and penetration enhancers, wherein the pharmaceutical compositions are formulated as creams for topical administration. In some embodiments, the transdermal pharmaceutical compositions contain progesterone, a medium-chain oil, and d-limonene. In some embodiments, the transdermal pharmaceutical compositions contain progesterone, a medium-chain oil, a penetration enhancer (e.g., propylene glycol, a fatty acid ester of propylene glycol, a glycol ether), and optionally d-limonene. In certain embodiments, the pharmaceutical compositions further include estradiol. Methods for treating conditions associated with hormone deficiency in a subject are also described.
    Type: Application
    Filed: July 29, 2015
    Publication date: February 4, 2016
    Inventors: PETER PERSICANER, JULIA AMADIO, AJAY K. GHANTA, JASON D. LEGASSIE, ANNETTE SHADIACK, THORSTEINN THORSTEINSSON, RICHARD WINNEKER
  • Patent number: 8247530
    Abstract: A melanocortin-4 receptor agonist cyclic peptide of the formula where R1, R2, R3, R4a, R4b, R5, R6, R7a, R7b, x, y and z are as defined in the specification, and a method of treating sexual dysfunction, including male erectile dysfunction and female sexual dysfunction, and other melanocortin 4 receptor responsive conditions and disorders.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: August 21, 2012
    Assignee: Palatin Technologies, Inc.
    Inventors: Shubh D. Sharma, Yi-Qun Shi, Kevin D. Burris, Annette Shadiack, Ramesh Rajpurohit
  • Publication number: 20110009341
    Abstract: A melanocortin-4 receptor agonist cyclic peptide of the formula where R1, R2, R3, R4a, R4b, R5, R6, R7a, R7b, x, y and z are as defined in the specification, and a method of treating sexual dysfunction, including male erectile dysfunction and female sexual dysfunction, and other melanocortin 4 receptor responsive conditions and disorders.
    Type: Application
    Filed: November 7, 2006
    Publication date: January 13, 2011
    Applicant: PALATIN TECHNOLOGIES, INC.
    Inventors: Shubh D. Sharma, Yi-Qun Shi, Kevin D. Burris, Annette Shadiack, Ramesh Rajpurohit
  • Patent number: 7307063
    Abstract: Metallopeptides are provided for use in treatment of sexual dysfunction in mammals. The metallopeptides are agonists for at least one of melanocortin-3 or melanocortin-4 receptors. The metallopeptides are conformationally fixed on complexation of a metal ion-binding portion thereof with a metal ion. Also provided are metallopeptides that are antagonists for at least one of melanocortin-3 or melanocortin-4 receptors.
    Type: Grant
    Filed: August 13, 2003
    Date of Patent: December 11, 2007
    Assignee: Palatin Technologies, Inc.
    Inventors: Shubh Sharma, Annette Shadiack, Yi-Qun Shi, Wei Yang, Hui-Zhi Cai
  • Patent number: 7176279
    Abstract: A cyclic peptide with a C-terminus —OH group. Further provided are compositions and methods for treatment of sexual dysfunction in mammals, including male sexual dysfunction, such as erectile dysfunction, and female sexual dysfunction, by administration of a cyclic peptide including a C-terminus —OH group. Methods of administration include injection, oral, urethral, vaginal, nasal and mucosal administration.
    Type: Grant
    Filed: August 8, 2003
    Date of Patent: February 13, 2007
    Assignee: Palatin Technologies, Inc.
    Inventors: Shubh Sharma, Annette Shadiack, Ramesh Rajpurohit, Wei Yang