Patents by Inventor Annick Ballay

Annick Ballay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adenoviral vector with a deletion in the E1A coding region expressing a hetorologous protein
    Patent number: 6696420
    Abstract: Recombinant DNA modified by a nucleotide sequence coding for a specific polypeptide sequence whose expression is sought, this recombinant DNA being appropriate to the transformation of eucaryotic cell lines, notably human or animal, the endogenous polymerases of which are susceptible of recognizing the adenovirus promoters. The DNA according to the invention is more particularly characterized by the fact that the said insertion nucleotide sequence is placed under the direct control of the early promoter of the E1A region of the genome of adenovirus.
    Type: Grant
    Filed: July 20, 1993
    Date of Patent: February 24, 2004
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique, Institut National de la Sante et de la Recherche Medicale
    Inventors: Michel Perricaudet, Annick Ballay, Massimo Levredo, Pierre Tiollais
  • Defective recombinant adenovirus lacking E1A coding sequence and comprising a heterologous nucleotide sequence under control of the E1A promoter
    Patent number: 6426216
    Abstract: Recombinant DNA modified by a nucleotide sequence coding for a specific polypeptide sequence whose expression is sought, this recombinant DNA being appropriate to the transformation of eucaryotic cell lines, notably human or animal, the endogenous polymerases of which are susceptible of recognizing the adenovirus promoters. The DNA according to the invention is more particularly characterized by the fact that the said insertion nucleotide sequence is placed under the direct control of the early promoter of the E1A region of the genome of adenovirus.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: July 30, 2002
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique, Institut National de la Sante et de la Recherche Medicale
    Inventors: Michel Perricaudet, Annick Ballay, Massimo Levredo, Pierre Tiollais
  • Expression in non-tumoral human lymphoblastoid lines with an integrative vector
    Patent number: 5789247
    Abstract: A plasmid vector designed for transforming lymphoblastoid cells, immortalized by Epstein Barr virus, for producing heterologous proteins, which comprises the bacterial DNA elements required for its amplification together with the following DNA fragments:the DNA elements which constitute an expression cassette allowing the insertion of a heterologous DNA to be expressed in the human lymphoblastoid cells,the Adenovirus 5 derived DNA sequence encoding the VA I and VA II RNA aimed at optimizing the messenger RNA translation,a gene engineered to be efficient as a selective marker in eukaryotic cells, andDNA segments selected for their property to promote plasmid DNA integration into the cell chromosome DNA.
    Type: Grant
    Filed: October 12, 1994
    Date of Patent: August 4, 1998
    Inventors: Annick Ballay, Georges Boffa, Jean-Pierre Cartron, Stany Chretien, Patrick Lambin, Claude Lopez, Sylvie Prigent, Charles Salmon