Abstract: The present disclosure provides a class of conjugates of general formula (X), a class of TLR9 agonist derivatives, such as formula (I), (XX), and (XXI), certain diastereomers of STING agonists, a class of STING agonist derivatives, such as formula (XXVIV), a class of heterocyclic compounds of general formula (II), a class of heterocyclic compounds of general formula (III), as defined herein. A1, A2, T, Z1, Z2, Z3, b1, and b2, in formula (X) are defined herein. The conjugate provides unique properties that are based upon the properties of the therapeutic agents that are part of the conjugate. Also provided are methods of synthesis and use of compounds.

Abstract: The present disclosure provides a data accessing method applied to a PCIe storage device. The method comprises: receiving a data reading/writing request sent by a host; calculating a physical storage location of data to be accessed, based on the data reading/writing request, wherein the physical storage location comprises a plurality of PCIe storage devices communicating according to a network protocol; acquiring the data from the plurality of PCIe storage devices based on the network protocol and transferring the data to the host. Also, the disclosure provides a PCIe storage device. With the solution of the disclosure, a PCIe storage device is enabled to access both local and cloud storages, the small-capacity problem with the local storage is addressed and operations of a host's operating system for managing two different types of heterogeneous storages are simplified.

Abstract: The present disclosure provides a data accessing method applied to a PCIe storage device. The method comprises: receiving a data reading/writing request sent by a host; calculating a physical storage location of data to be accessed, based on the data reading/writing request, wherein the physical storage location comprises a plurality of PCIe storage devices communicating according to a network protocol; acquiring the data from the plurality of PCIe storage devices based on the network protocol and transferring the data to the host. Also, the disclosure provides a PCIe storage device. With the solution of the disclosure, a PCIe storage device is enabled to access both local and cloud storages, the small-capacity problem with the local storage is addressed and operations of a host's operating system for managing two different types of heterogeneous storages are simplified.