Patents by Inventor Anthony David Woolhouse

Anthony David Woolhouse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of DNMT1 as anticancer therapeutic agents
    Patent number: 11518779
    Abstract: Provided herein are inhibitors of DNA methyltransferase 1 (an enzyme responsible for the maintenance of DNA CpG methylation marks in human cells) and their use for inhibiting DNA methyltransferase 1. The invention relates to compounds, pharmaceutical compositions, and methods for inhibiting DNA methyltransferase 1.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: December 6, 2022
    Assignees: Victoria Link Limited, Albert Einstein College of Medicine
    Inventors: Peter Charles Tyler, Farah Lamiable-Oulaidi, Anthony David Woolhouse, Shivali Ashwin Gulab, Karl Jürgen Shaffer, Ashna Ashneen Khan, Douglas Ronald Crump, Vern L. Schramm, Quan Du
  • INHIBITORS OF DNMT1 AS ANTICANCER THERAPEUTIC AGENTS
    Publication number: 20210206795
    Abstract: Inhibitors of DNA methyltransferase 1 (an enzyme responsible for the maintenance of DNA CpG methylation marks in human cells) and their use as therapeutic agents against various cancers. The invention relates to compounds, pharmaceutical compositions, methods for inhibiting DNA methyltransferase 1, and methods for treating cancer. The inhibitors are compounds of the general formula.
    Type: Application
    Filed: July 9, 2019
    Publication date: July 8, 2021
    Inventors: Peter Charles Tyler, Farah Lamiable-Oulaidi, Anthony David Woolhouse, Shivali Ashwin Gulab, Karl Jürgen Shaffer, Ashna Ashneen Khan, Douglas Ronald Crump, Vern L. Schramm, Quan Du
  • Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases
    Patent number: 8853224
    Abstract: The invention relates to compounds of the general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNPs) and/or nucleoside hydrolases (NHs). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: October 7, 2014
    Assignees: Industrial Research Limited, Albert Einstein College of Medicine of Yeshiva University
    Inventors: Keith Clinch, Gary Brian Evans, Richard Hubert Furneaux, Shivali Ashwin Gulab, Peter Michael Kelly, Vern L. Schramm, Peter Charles Tyler, Anthony David Woolhouse
  • Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases
    Publication number: 20110130412
    Abstract: The invention relates to compounds of the general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNPs) and/or nucleoside hydrolases (NHs). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.
    Type: Application
    Filed: September 7, 2007
    Publication date: June 2, 2011
    Inventors: Keith Clinch, Gary Brian Evans, Richard Hubert Furneaux, Shivali Ashwin Gulab, Peter Michael Kelly, Vern L. Schramm, Peter Charles Tyler, Anthony David Woolhouse