Abstract: Provided herein are processes, including semi-synthetic, and synthetic processes for preparing cannabinoids, and cannabinoid compositions provided thereby.

Abstract: Provided herein are processes, such as commercially viable processes, of producing alkyl resorcinols, such as olivetol and olivetolic acid, and analogs of each thereof. Certain of these processes utilize a recombinant, heterologous host microorganism. Certain of the heterologous microorganisms include a Cannabis sativa olivetol synthase (which is a tetraketide synthase, csOLS). Certain of the heterologous microorganisms include a Cannabis sativa olivetolic acid cyclase (csOAC). Certain of the heterologous microorganisms include a Cannabis sativa acyl activating enzyme (csAAE), such as, without limitation, csAAE1. In certain of these processes, glucose is fermented. In certain of these processes, the fermentation further comprises a carboxylic acid, RCO2H where R is defined as herein, or a salt thereof. Certain of these processes provide olivetol and olivetolic acid in a combined amount of at least 3 g/liter.

Abstract: The present invention provides recombinant gram-negative host cells that do not degrade protease-sensitive recombinant proteins yet grow to high cell density, methods for the use of these host cells to produce high-quality recombinant proteins, including antibodies and antibody fragments, at high yield, as well as compositions and methods relating to periplasmic expression of recombinant proteins or polypeptides of interest in host cells.

Abstract: Disclosed is a composition comprising a nicking enzyme and a water-soluble rubidium salt, and a method of performing a reaction catalysed by a nicking enzyme including the presence of a water-soluble rubidium salt in the reaction.

Abstract: A projectile having a spin stabilized gyroscopically stable flight path due to a base flange. With the base flange, the aerodynamic overturning moment about the center of gravity is reduced to increase the gyroscopic stability factor for stable flight. In one application, a medium-caliber untethered human electro-muscular incapacitation (HEMI) projectile has improved effectiveness due to its stable flight from launch to targets. Other applications for damping resulted in significant improvement in ground dispersion of 40 mm projectiles. The increased stability and increased aerodynamic damping reduce coning motion during flight which ensures that the projectile arrives at the target with greater accuracy, and with its nose oriented for effective incapacitation of the target.

Abstract: A cooler sled device for facilitating transport of a cooler over surfaces such as gravel, loose terrain, and sand includes a panel. A bottom surface of the panel is convexly curved between outer sides of a perimeter edge of the panel and extending rearwardly from a front side of the perimeter edge defining an upwardly turned front section of the bottom surface. Each of a pair of wells is positioned on an upper surface of the panel and proximate a respective one of the outer sides of the perimeter edge for receiving wheels coupled to a cooler positioned on the panel. A strap is positionable to extends across the upper surface of the panel for securing the cooler on the panel.

Abstract: A cooler sled device for facilitating transport of a cooler over surfaces such as gravel, loose terrain, and sand includes a panel. A bottom surface of the panel is convexly curved between outer sides of a perimeter edge of the panel and extending rearwardly from a front side of the perimeter edge defining an upwardly turned front section of the bottom surface. Each of a pair of wells is positioned on an upper surface of the panel and proximate a respective one of the outer sides of the perimeter edge for receiving wheels coupled to a cooler positioned on the panel. A strap is positionable to extends across the upper surface of the panel for securing the cooler on the panel.

Abstract: A kinetic energy training cartridge simulates the performance, weight, length, and external geometry of a tactical cartridge. The training cartridge includes a cartridge case and a projectile that is secured to cartridge case by means of a sabot. The sabot includes a rearward extension that encapsulates part of the projectile, to add weight and to increase a length to diameter ratio of the projectile, so as to decrease an intrusion volume of the projectile within the cartridge case. In a preferred embodiment, the length to diameter ratio of the projectile is at least 15.

Abstract: A finless cone-nosed, ogival-nosed, or combination ogive-cone nosed training projectile is statically stable, yet has adequate spin rate to compensate for aerodynamic or mass asymmetries. In addition, the training projectile can be fired from smooth bore or rifled cannons of various calibers, including 120 mm and 105 mm. Spin torque and stability augmentation are provided by a radially angled slotted tail flange attached to the rear of the training projectile, providing high performance and improved accuracy at low cost for use in training exercises. The training projectile has a higher static margin than conventional devices, and provides the ability to train personnel with a training projectile that achieves flight ranges similar to its matching tactical projectile, and has improved accuracy.

Abstract: A finless cone-nosed, ogival-nosed, or combination ogive-cone nosed training projectile is statically stable, yet has adequate spin rate to compensate for aerodynamic or mass asymmetries. In addition, the training projectile can be fired from smooth bore or rifled cannons of various calibers, including 120 mm and 105 mm. Spin torque and stability augmentation are provided by a radially angled slotted tail flange attached to the rear of the training projectile, providing high performance and improved accuracy at low cost for use in training exercises. The training projectile has a higher static margin than conventional devices, and provides the ability to train personnel with a training projectile that achieves flight ranges similar to its matching tactical projectile, and has improved accuracy.

Abstract: A guidance device for projectiles has stationary canards (40) and thrusters (50) positioned on the nose (20) of the projectile (10). The thrusters (50) are initiated from remote or local sensor to provide flight maneuverability to a target.

Abstract: An aerodynamic device, such as a projectile includes an elongated forebody, and an aft section secured to the forebody. The aft section acts as a d control device, and includes a connecting member that extends integrally in a conically shaped flared section, for generating a lift force to help stabilize the projectile during forward flight. The aft section further includes a flange that extends from the flared section, and that provides velocity decay and optimal drag, in order to limit the projectile flight and descent within a predetermined safety or emergency range. The flared section is defined between an innermost edge positioned adjacent to the connecting member, and an outermost edge positioned adjacent to the flange.

Abstract: A projectile to be, fired from a non-rifled tube includes an elongated foody and a stabilizer secured to the tail end of the forebody for enhancing the projectile flight stability and for imparting spin to the projectile. The stabilizer includes a threaded member that extends integrally into a forward section, a peripheral channel and a grooved aft section. The forward section has a generally smooth cylindrical shape. The peripheral channel extends along the entire peripheral contour of the stabilizer and has a generally semi-circular cross-section, for generating an expansion wave and for directing air flow toward the grooved aft section. The grooved aft section is cylindrically shaped relative to a longitudinal axis, and has a predetermined number of identical, equally spaced, circumferentially positioned grooves which traverse the entire axial length of the aft section, and which are angled relative to the longitudinal axis. Each angled groove is defined by two substantially parallel side walls.

Abstract: The disclosure is of a projectile having a main body, a nose and a tail iuding a flared tail member, the projectile having its center of gravity close to the nose thereof.

Abstract: A cylindrical device connected to the nose of a projectile for imparting n to the projectile fired from a non-rifled bore of a cannon. The device has at least two coaxial, adjacent, and integrally connected cylindrical segments of different diameter. The segment having the larger diameter is positioned most rearwardly of the projectile, relative to the nose of the projectile, and the periphery of this segment has circumferentially spaced angled slots for catching air moving past the projectile to spin the projectile. The segment with the smaller diameter attaches the cylindrical device to the aft end of the nose of the projectile and directs the flow of air to and through the angled slots of the segment having the larger diameter.