Abstract: Relapsing remitting multiple sclerosis (RRMS) is the most common form of multiple sclerosis, affecting more than 80% of MS patients. RRMS is comprised of two phases: the auto-inflammatory episodes, in which the immune system is actively destroying myelin, alternate with remission phases. Currently there is no cure for this devastating disease. The present disclosure provides compositions and methods useful for inducing remyelination. The methods are useful for promoting remyelination to treat diseases and disorders such as MS. The present disclosure describes compositions and methods useful for inhibiting LRP1 activity. In one aspect, a siRNA against LRP1 can be used. It is disclosed that myelination can be regulated by inhibiting the interaction of LRP1 and p75NTR and that it inhibits activation of Rho-A.

Abstract: Provided herein are processes for ethylene oligomerization in the presence of an ionic liquid catalyst and a co-catalyst to produce a hydrocarbon product comprising C10-C55 oligomers.

Abstract: Devices having an air bearing surface (ABS), the devices include a write pole; a near field transducer (NFT) including a peg and a disc, wherein the peg is at the ABS of the device; an overcoat, the overcoat including a low surface energy layer.

Abstract: Provided herein are processes for ethylene oligomerization in the presence of an ionic liquid catalyst and a co-catalyst to produce a hydrocarbon product comprising C10-C55 oligomers.

Abstract: Provided herein are processes for ethylene oligomerization in the presence of an ionic liquid catalyst and a co-catalyst to produce a hydrocarbon product comprising C10-C55 oligomers.

Abstract: A method of cleaning a recording medium, such as a disc. The method includes contacting a surface of the recording medium with a cleaning tape comprising a flexible backing and a self-assembled monolayer (SAM) coating. The cleaning tape may include an abrasive coating, with the SAM on the abrasive coating.

Abstract: Provided herein are processes for ethylene oligomerization in the presence of an ionic liquid catalyst and a co-catalyst to produce a hydrocarbon product comprising C10-C55 oligomers.

Abstract: Devices having an air bearing surface (ABS), the devices include a write pole; a near field transducer (NFT) including a peg and a disc, wherein the peg is at the ABS of the device; an overcoat, the overcoat including a low surface energy layer.

Abstract: A slider for a data recording device such as a disc drive. The slider has a pattern, which can be a micro-pattern, of SAM material on the air-bearing surface (ABS). The pattern comprises discrete unconnected features, such as dots or lines, that may or may no cover the entire ABS. Methods of micro-printing on the ABS are also provided.

Abstract: Methods for providing a SAM (self-assembled monolayer) coating on a slider and subsequently removing a portion of the SAM coating. In one implementation, the method includes applying a SAM coating on at least a first surface of a slider and on a second surface of the slider opposite the first surface, and removing at least a portion of the SAM coating from the second surface by irradiating the second surface with UV radiation in a wavelength range of 100-200 nm.

Abstract: A method of cleaning a recording medium, such as a disc. The method includes contacting a surface of the recording medium with a cleaning tape comprising a flexible backing and a self-assembled monolayer (SAM) coating. The cleaning tape may include an abrasive coating, with the SAM on the abrasive coating.

Abstract: The invention relates to a smart integration of dual Architecture Contact-less SIM into mobile devices and describes the method of performing various economic transactions more efficiently using a smart and interactive poster device.

Abstract: A system includes a first database, a second database, a third database, and an application server. The first database server includes a database instance. The second database server is in communication with the first database server. The second database server includes a mirror of the database instance. The third database server is in communication with the second database server. The third database server is configured to store a copy of a database within the database instance. The application server is configured to be placed in communication with the first, second, and third database servers, configured to fail over between the first and second database servers, and further configured to fail over between the second and third database servers.

Abstract: A storage system includes a storage controller, a storage array coupled to the storage controller, and a temporary storage device coupled to the storage controller. The storage array is operated as a redundant array of independent drives (RAID) array and includes a high priority storage volume and a low priority storage volume. The storage controller stores high priority data transfers on the high priority volume, stores low priority data transfers on the temporary storage device, and moves the low priority data transfers to the low priority volume in response to a condition of the storage system.

Abstract: A semiconductor device includes a substrate, a die assembly attachable to the substrate and a flexible strip extending over the substrate and the die assembly. The flexible strip has one or more routing circuits carried thereon. The die assembly and the substrate are arranged to be electrically connected through the one or more routing circuits carried on the flexible strip.

Abstract: A semiconductor device includes a substrate, a die assembly attachable to the substrate and a flexible strip extending over the substrate and the die assembly. The flexible strip has one or more routing circuits carried thereon. The die assembly and the substrate are arranged to be electrically connected through the one or more routing circuits carried on the flexible strip.

Abstract: A semiconductor device includes a substrate, a die assembly attachable to the substrate and a flexible strip extending over the substrate and the die assembly. The flexible strip has one or more routing circuits carried thereon. The die assembly and the substrate are arranged to be electrically connected through the one or more routing circuits carried on the flexible strip.

Abstract: A system includes a first database, a second database, a third database, and an application server. The first database server includes a database instance. The second database server is in communication with the first database server. The second database server includes a mirror of the database instance. The third database server is in communication with the second database server. The third database server is configured to store a copy of a database within the database instance. The application server is configured to be placed in communication with the first, second, and third database servers, configured to fail over between the first and second database servers, and further configured to fail over between the second and third database servers.

Abstract: The invention relates to a smart integration of dual Architecture Contact-less SIM into mobile devices and describes the method of performing various economic transactions more efficiently using a smart and interactive poster device.

Abstract: An integrated circuit package includes a flexible laminar substrate 1. The substrate 1 has a flexible layer 5 of heat conductive material on one of its faces. The layer 5 extends across an aperture 9 in the flexible substrate 1. A first integrated circuit 11 is mounted on the layer 5 within the aperture 9, and wire bonded to the substrate 1. A flip chip 21 is mounted on the first integrated circuit 11. The two integrated circuits 11, 21 are embedded in a resin body 23.