Patents by Inventor Anthony Klos

Anthony Klos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION COMPRISING HIGHLY-CONCENTRATED ALPHA1 PROTEINASE INHIBITOR AND METHOD FOR OBTAINING THEREOF
    Publication number: 20230277636
    Abstract: Compositions include highly concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).
    Type: Application
    Filed: May 12, 2023
    Publication date: September 7, 2023
    Inventors: James REBBEOR, Charles MILLER, Anthony KLOS, Eric ALLGAIER, Thomas P. ZIMMERMAN, Kevin WEE, Michelle StPETER, Kelly GLANCY
  • Composition comprising highly-concentrated ?1 proteinase inhibitor and method for obtaining thereof
    Patent number: 11701412
    Abstract: Compositions include highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly-concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).
    Type: Grant
    Filed: September 22, 2021
    Date of Patent: July 18, 2023
    Assignee: GRIFOLS WORLDWIDE OPERATIONS LIMITED
    Inventors: James Rebbeor, Charles Miller, Anthony Klos, Eric Allgaier, Thomas P. Zimmerman, Kevin Wee, Michelle StPeter, Kelly Glancy
  • Composition comprising highly-concentrated ALPHA1 proteinase inhibitor and method for obtaining thereof
    Patent number: 11253578
    Abstract: Compositions include highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly-concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: February 22, 2022
    Assignee: GRIFOLS WORLDWIDE OPERATIONS LIMITED
    Inventors: James Rebbeor, Charles Miller, Anthony Klos, Eric Allgaier, Thomas P. Zimmerman, Kevin Wee, Michelle StPeter, Kelly Glancy
  • COMPOSITION COMPRISING HIGHLY-CONCENTRATED ALPHA1 PROTEINASE INHIBITOR AND METHOD FOR OBTAINING THEREOF
    Publication number: 20220000992
    Abstract: Compositions include highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly-concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).
    Type: Application
    Filed: September 22, 2021
    Publication date: January 6, 2022
    Inventors: JAMES REBBEOR, CHARLES MILLER, ANTHONY KLOS, ERIC ALLGAIER, THOMAS P. ZIMMERMAN, KEVIN WEE, MICHELLE StPETER, KELLY GLANCY
  • COMPOSITION COMPRISING HIGHLY-CONCENTRATED ALPHA1 PROTEINASE INHIBITOR AND METHOD FOR OBTAINING THEREOF
    Publication number: 20200038494
    Abstract: Compositions include highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly-concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).
    Type: Application
    Filed: August 1, 2019
    Publication date: February 6, 2020
    Inventors: JAMES REBBEOR, CHARLES MILLER, ANTHONY KLOS, ERIC ALLGAIER, THOMAS P. ZIMMERMAN, KEVIN WEE, MICHELLE StPETER, KELLY GLANCY
  • Composition, method, and kit for alpha-1 proteinase inhibitor
    Patent number: 9616126
    Abstract: The present invention provides compositions comprising API and at least one amino acid, in particular a liquid API formulation comprising amino acids, and methods and kits related thereto. These amino acids when incorporated into the API composition afford stability to the API formulation.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: April 11, 2017
    Assignee: Grifols Therapeutics, Inc.
    Inventors: Jianxin Guo, Anthony Klos, Bret Coldren, Deborah Barnette, Mark Manning
  • COMPOSITION, METHOD, AND KIT FOR ALPHA-1 PROTEINASE INHIBITOR
    Publication number: 20160106843
    Abstract: The present invention provides compositions comprising API and at least one amino acid, in particular a liquid API formulation comprising amino acids, and methods and kits related thereto. These amino acids when incorporated into the API composition afford stability to the API formulation.
    Type: Application
    Filed: October 29, 2015
    Publication date: April 21, 2016
    Applicant: Grifols Therapeutics Inc.
    Inventors: Jianxin Guo, Anthony Klos, Bret Coldren, Deborah Barnette, Mark Manning
  • Lyophilization methods, compositions, and kits
    Patent number: 8648177
    Abstract: Method for lyophilization is provided, in particular methods for lyophilization of formulations comprising AT III. Also provided are compositions prepared by therefrom. Also provided are kits comprising the compositions and/or lyophilized products.
    Type: Grant
    Filed: November 23, 2010
    Date of Patent: February 11, 2014
    Assignee: Grifols Therapeutics Inc.
    Inventors: Jianxin Guo, Anthony Klos, Deborah Barnette
  • COMPOSITION, METHOD, AND KIT FOR ALPHA-1 PROTEINASE INHIBITOR
    Publication number: 20130131192
    Abstract: The present invention provides compositions comprising API and at least one amino acid, in particular a liquid API formulation comprising amino acids, and methods and kits related thereto. These amino acids when incorporated into the API composition afford stability to the API formulation.
    Type: Application
    Filed: November 2, 2010
    Publication date: May 23, 2013
    Inventors: Jianxin Guo, Anthony Klos, Bret Coldren, Deborah Barnette, Mark Manning
  • LYOPHILIZATION METHODS, COMPOSITIONS, AND KITS
    Publication number: 20130040890
    Abstract: Method for lyophilization is provided, in particular methods for lyophilization of formulations comprising AT III. Also provided are compositions prepared by therefrom. Also provided are kits comprising the compositions and/or lyophilized products.
    Type: Application
    Filed: November 23, 2010
    Publication date: February 14, 2013
    Inventors: Jianxin Guo, Anthony Klos, Deborah Barnette