Patents by Inventor Anthony L. Kuczynski

Anthony L. Kuczynski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for administering drug to gastrointestinal tract
    Patent number: 5785994
    Abstract: A dosage form is disclosed that comprises means inside the dosage form for providing a substantially drug-free interval before the dosage form delivers a drug from inside the dosage form. The dosage form in an embodiment comprises a drug on the exterior of the dosage form, which drug is available for immediate delivery.
    Type: Grant
    Filed: April 1, 1992
    Date of Patent: July 28, 1998
    Assignee: ALZA Corporation
    Inventors: Patrick S.-L. Wong, Felix Theeuwes, Atul Devdatt Ayer, Anthony L. Kuczynski
  • Hydromorphone therapy
    Patent number: 5702725
    Abstract: A hydromorphone composition, a hydromorphone dosage form and a method for administering hydromorphone are disclosed, indicated for the management of pain.
    Type: Grant
    Filed: March 5, 1996
    Date of Patent: December 30, 1997
    Assignee: Alza Corporation
    Inventors: Sonya Merrill, Atul Devdatt Ayer, Navjot Chadha, Anthony L. Kuczynski
  • Morphine therapy
    Patent number: 5667805
    Abstract: A composition comprising morphine; and a dosage form comprising morphine are disclosed for morphine therapy. A method of using the composition and the dosage form are disclosed and indicated for morphine therapy.
    Type: Grant
    Filed: October 4, 1996
    Date of Patent: September 16, 1997
    Assignee: Alza Corporation
    Inventors: Sonya Merrill, Atul Devdatt Ayer, Paul Hwang, Anthony L. Kuczynski
  • Effective therapy for epilepsies
    Patent number: 5660861
    Abstract: A dosage form is disclosed for delivering an antiepileptic drug, which dosage form comprises for maintaining the integrity of the dosage form and of the antiepileptic drug.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: August 26, 1997
    Assignee: ALZA Corporation
    Inventors: Frank Jao, Patrick S.-L. Wong, Evangeline Cruz, Eduardo C. Sy, Anthony L. Kuczynski
  • Morphine therapy
    Patent number: 5593695
    Abstract: A therapeutic tablet comprising morphine, poly(alkylene oxide) and poly(vinylpyrrolidone) encased by a composition comprising a cellulose polymer.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: January 14, 1997
    Assignee: ALZA Corporation
    Inventors: Sonya Merrill, Atul D. Ayer, Paul Hwang, Anthony L. Kuczynski
  • Method for lowering blood glucose
    Patent number: 5591454
    Abstract: The invention disclosed comprises a method for administering the antidiabetic drug glipizide to a patient in need of glipizide in need of antidiabetic therapy.
    Type: Grant
    Filed: May 16, 1995
    Date of Patent: January 7, 1997
    Assignee: ALZA Corporation
    Inventors: Anthony L. Kuczynski, Atul D. Ayer, Patrick S.-L. Wong
  • Dosage form for administering oral hypoglycemic glipizide
    Patent number: 5545413
    Abstract: A dosage form is disclosed comprising the antidiabetic drug glipizide for administering to a patient in need of glipizide therapy.
    Type: Grant
    Filed: January 22, 1991
    Date of Patent: August 13, 1996
    Assignee: Alza Corporation
    Inventors: Anthony L. Kuczynski, Atul D. Ayer, Patrick S. Wong
  • Hydromorphone therapy
    Patent number: 5529787
    Abstract: A hydromorphone composition, a hydromorphone dosage form and a method for administering hydromorphone are disclosed, indicated for the management of pain.
    Type: Grant
    Filed: July 7, 1994
    Date of Patent: June 25, 1996
    Assignee: Alza Corporation
    Inventors: Sonya Merrill, Atul D. Ayer, Navjot Chadha, Anthony L. Kuczynski
  • Morphine therapy
    Patent number: 5460826
    Abstract: A bilayer comprising a morphine layer of morphine, poly(alkylene oxide) and poly(vinylpyrrolidone); and an expandable contacting layer of coated granules of a higher molecular weight poly(alkylene oxide) and a hydroxyalkylcellulose, which bilayer is disclosed for morphine therapy. A method is disclosed for using the bilayer composition.
    Type: Grant
    Filed: June 27, 1994
    Date of Patent: October 24, 1995
    Assignee: Alza Corporation
    Inventors: Sonya Merrill, Atul D. Ayer, Paul Hwang, Anthony L. Kuczynski
  • Antiviral therapy
    Patent number: 5358721
    Abstract: A dosage form is disclosed for administering an antiviral drug to a patient in need of antiviral therapy.
    Type: Grant
    Filed: December 4, 1992
    Date of Patent: October 25, 1994
    Assignee: Alza Corporation
    Inventors: George V. Guittard, Patrick S. L. Wong, Anthony L. Kuczynski, David J. Kidney
  • Controlled release dispenser comprising beneficial agent
    Patent number: 5273752
    Abstract: A dispenser is disclosed for delivering a beneficial agent in a hydrophilic carrier formulation to an animal in a rate-controlled manner. The dispenser comprises (1) a semipermeable housing defining an internal space, (2) at least one composition comprising a beneficial agent and a pharmaceutically acceptable hydrophilic carrier in the space, (3) an expandable hydrophilic driving member in the space, (4) a density member in the space, and (5) one exit passageway or a multiplicity of exit passageways in the housing for delivering the beneficial agent from the dispenser, the diameter of each exit passageway being of a size to maximize release of the beneficial agent by osmotic pumping and to minimize release of the beneficial agent by diffusion or erosion to substantially avoid mechanical agitation-dependent release of the beneficial agent.
    Type: Grant
    Filed: September 19, 1991
    Date of Patent: December 28, 1993
    Assignee: Alza Corporation
    Inventors: Atul D. Ayer, Terry L. Burkoth, Anthony L. Kuczynski, Joseph C. Deters
  • Dosage form for time-varying patterns of drug delivery
    Patent number: 5232705
    Abstract: A dosage form is disclosed that comprises means inside the dosage form for providing a substantially drug-free interval before the dosage form delivers a drug from inside the dosage form. The dosage form in an embodiment comprises a drug on the exterior of the dosage form, which drug is available for immediate delivery.
    Type: Grant
    Filed: April 1, 1992
    Date of Patent: August 3, 1993
    Assignee: Alza Corporation
    Inventors: Patrick S. Wong, Felix Theeuwes, Atul D. Ayer, Anthony L. Kuczynski
  • Dosage form for time-varying patterns of drug delivery
    Patent number: 5156850
    Abstract: A dosage form is disclosed that comprises means inside the dosage form for providing a substantially drug-free interval before the dosage form delivers a drug from inside the dosage form. The dosage form in an embodiment comprises a drug on the exterior of the dosage form, which drug is available for immediate delivery.
    Type: Grant
    Filed: August 31, 1990
    Date of Patent: October 20, 1992
    Assignee: ALZA Corporation
    Inventors: Patrick S. Wong, Felix Theeuwes, Atul D. Ayer, Anthony L. Kuczynski
  • Dispenser comprising ionophore
    Patent number: 5126142
    Abstract: A dispenser is disclosed for delivering a beneficial ionophore to an animal. The dispenser comprises (1) a semipermeable housing defining an internal space, (2) at least one composition comprising an ionophore and a pharmaceutically acceptable carrier in the space, (3) an expandable hydrophilic composition in the space, (4) a dense member in the space, and (5) at least one exit passageway in the housing for delivering the ionophore from the dispenser.
    Type: Grant
    Filed: January 11, 1991
    Date of Patent: June 30, 1992
    Assignee: ALZA Corporation
    Inventors: Atul D. Ayer, Terry L. Burkoth, Anthony L. Kuczynski, Joseph C. Deters
  • Delivery system for administration blood-glucose lowering drug
    Patent number: 5091190
    Abstract: A dosage form is disclosed comprising the antidiabetic drug glipizide for administering to a patient in need of glipizide therapy.
    Type: Grant
    Filed: February 8, 1991
    Date of Patent: February 25, 1992
    Assignee: ALZA Corporation
    Inventors: Anthony L. Kuczynski, Atul D. Ayer, Patrick S. Wong
  • Long-term delivery device including loading dose
    Patent number: 5045082
    Abstract: The invention provides a long-term dispensing device comprising a first agent delivery means for short-term and continuous delivery of agent, retained together with a second agent delivery means capable of long-term and continuous delivery of agent. The combination of first and second agent delivery means provides a device in which a substantially constant dose of beneficial agent is delivered to the environment of use over time. A rapid delivery of beneficial agent is followed by continuous and prolonged delivery of agent.
    Type: Grant
    Filed: January 10, 1990
    Date of Patent: September 3, 1991
    Assignee: Alza Corporation
    Inventors: Atul D. Ayer, James B. Eckenhoff, Jeremy C. Wright, Anthony L. Kuczynski
  • Dosage form for delivering soluble or insoluble drugs
    Patent number: 5035897
    Abstract: A dosage form is disclosed comprising granule means for delivering soluble to insoluble drug to a warm-blooded animal.
    Type: Grant
    Filed: September 5, 1989
    Date of Patent: July 30, 1991
    Assignee: Alza Corporation
    Inventors: Atul D. Ayer, Anthony L. Kuczynski, Patrick S. Wong
  • Dosage form for treating cardiovascular diseases
    Patent number: 5030456
    Abstract: An osmotic device is disclosed comprising a first composition, and a second composition with the beneficial drug isradipine in the first composition.
    Type: Grant
    Filed: April 30, 1990
    Date of Patent: July 9, 1991
    Assignee: ALZA Corporation
    Inventors: Atul D. Ayer, David R. Swanson, Anthony L. Kuczynski
  • Oral hypoglycemic glipizide granulation
    Patent number: 5024843
    Abstract: A dosage form is disclosed comprising the antidiabetic drug glipizide for administering to a patient in need of glipizide therapy.
    Type: Grant
    Filed: September 5, 1989
    Date of Patent: June 18, 1991
    Assignee: ALZA Corporation
    Inventors: Anthony L. Kuczynski, Atul D. Ayer, Patrick S.-L. Wong
  • Delivery dispenser for treating cardiac arrhythmias
    Patent number: 5019396
    Abstract: A dosage form is disclosed comprising a first composition comprising two different polyethylene oxide osmopolymers for delivering a drug at a controlled rate over time.
    Type: Grant
    Filed: May 12, 1989
    Date of Patent: May 28, 1991
    Assignee: ALZA Corporation
    Inventors: Atul D. Ayer, Anthony L. Kuczynski, Patrick S. L. Wong, Lawrence G. Hamel, Maureen L. Jordan