Patents by Inventor Anthony L. Riley

Anthony L. Riley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metal complexes for hypoxic cells
    Patent number: 5506345
    Abstract: Agents for the diagnosis or treatment of hypoxic cells comprise a bioreductive moiety such as 2-nitroimidazole, and a metal chelating moiety which is a bis-amine oxime of which a carbon atom adjacent a nitrogen atom is linked to the bioreductive moiety. A chelated metal atom or ion preferably Technetium-99m. The agent diffuses into cells where the 2-nitroimidazole is reduced thus trapping the chelated metal in the cell.
    Type: Grant
    Filed: July 25, 1994
    Date of Patent: April 9, 1996
    Assignee: Amersham International plc
    Inventors: Anthony L. Riley, James D. Kelly
  • Metal chelating ligands for hypoxic cells
    Patent number: 5387692
    Abstract: Agents for the diagnosis or treatment of hypoxic cells comprise a bioreductive moiety such as 2-nitroimidazole, and a metal chelating moiety which is a bis-amine oxime of which a carbon atom adjacent a nitrogen atom is linked to the bioreductive moiety. A chelated metal atom or ion preferably Technetium-99m. The agent diffuses into cells where the 2-nitroimidazole is reduced thus trapping the chelated metal in the cell.
    Type: Grant
    Filed: June 16, 1992
    Date of Patent: February 7, 1995
    Assignee: Amersham International plc
    Inventors: Anthony L. Riley, James D. Kelly