Abstract: The present invention relates to indoline-based compounds that inhibit Rho-associated protein kinase (ROCK) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of inhibiting ROCK activity and methods for treating, for example cerebral cavernous malformation syndrome (CCM) and cardiovascular diseases using the compounds and pharmaceutical compositions of the present invention.

Abstract: In an embodiment, a method for operating a target media device is described. The method includes receiving a user command by a remote control device for operating a target media device, where a signal to operate the target media device is not stored on the remote control device when the user command is received. Data associated with the user command is transmitted by the remote control device to a second media device and signal information, associated with the signal to operate the target media device, is received by the remote control device from the second media device. The signal to operate the target media device is transmitted by the remote control device to the target media device, where the target media device performs a function based on the signal received from the remote control device.

Abstract: A method includes detecting that a particular media device is communicatively coupled to one or more media devices in a set of media devices; in response to detecting that the particular media device is communicatively coupled to the one or more media devices in the set of media devices: automatically sending one or more remote operating codes, for remotely controlling the particular media device, to a remote control device.

Abstract: A method includes responsive to receiving a command to view multimedia content, displaying the multimedia content. A selection of a privacy level for the multimedia content is received, the privacy level indicating whether information associated with a user's viewing of the multimedia content may be published. A visual indicator of the privacy level is displayed concurrently with displaying the multimedia content.

Abstract: A method includes responsive to receiving a command to view multimedia content, displaying the multimedia content. A selection of a privacy level for the multimedia content is received, the privacy level indicating whether information associated with a user's viewing of the multimedia content may be published. A visual indicator of the privacy level is displayed concurrently with displaying the multimedia content.

Abstract: In an embodiment, a method for operating a target media device is described. The method includes receiving a user command by a remote control device for operating a target media device, where a signal to operate the target media device is not stored on the remote control device when the user command is received. Data associated with the user command is transmitted by the remote control device to a second media device and signal information, associated with the signal to operate the target media device, is received by the remote control device from the second media device. The signal to operate the target media device is transmitted by the remote control device to the target media device, where the target media device performs a function based on the signal received from the remote control device.

Abstract: An interface includes a blast plate having plate structure, the plate structure being formed to substantially conform to a certain portion of an exterior margin of a hull of a certain vehicle and being semi-permanently mounted to the hull by mounting to certain mounting devices present on the exterior margin of the hull and having mounting structure for supportively mounting a standardized add-on device, the mounting structure being designed to facilitate the add-on device being readily mountable on and demountable from the plate structure, the plate structure having structural characteristics for acting to protect the hull from effects of a blast directed at the hull. A modular assembly and a blast plate are further included.