Patents by Inventor Anthony P. Shuber

Anthony P. Shuber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of nucleic acids and proteins
    Patent number: 8852893
    Abstract: The invention generally relates to methods for detecting a target nucleic acid and a target protein in a single assay.
    Type: Grant
    Filed: June 5, 2012
    Date of Patent: October 7, 2014
    Assignee: Physicians Choice Laboratory Services, LLC
    Inventor: Anthony P. Shuber
  • Detection of nucleic acids and proteins
    Patent number: 8841095
    Abstract: The invention generally relates to methods for detecting a target nucleic acid and a target protein in a single assay.
    Type: Grant
    Filed: April 23, 2013
    Date of Patent: September 23, 2014
    Assignee: Physicians Choice Laboratory Services, LLC
    Inventor: Anthony P. Shuber
  • COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20140112944
    Abstract: This invention generally relates to compositions and methods for targeted delivery of chemotherapeutic agents to cancerous and pre-cancerous cells, thereby treating a cancer in a subject.
    Type: Application
    Filed: October 22, 2013
    Publication date: April 24, 2014
    Inventor: Anthony P. Shuber
  • DETECTION OF NUCLEIC ACIDS AND PROTEINS
    Publication number: 20130316356
    Abstract: The invention generally relates to methods for detecting a target nucleic acid and a target protein in a single assay.
    Type: Application
    Filed: August 6, 2013
    Publication date: November 28, 2013
    Applicant: Predictive Biosciences Corporation
    Inventors: Anthony P. Shuber, Eugene Chiu
  • PRIMERS FOR ANALYZING METHYLATED SEQUENCES AND METHODS OF USE THEREOF
    Publication number: 20130309667
    Abstract: Primers having abasic regions or mismatches for amplifying sequences suspected of having methylation. Primers having abasic regions or mismatches for amplifying sequences adjacent to suspected or known methylated sequences. Methods of using primers having abasic regions or mismatches for identification of methylated sequences or sequences adjacent to suspected or known methylation sequences.
    Type: Application
    Filed: April 5, 2013
    Publication date: November 21, 2013
    Inventor: Anthony P. Shuber
  • PRIMERS FOR ANALYZING METHYLATED SEQUENCES AND METHODS OF USE THEREOF
    Publication number: 20130310549
    Abstract: Primers having abasic regions or mismatches for amplifying sequences suspected of having methylation. Primers having abasic regions or mismatches for amplifying sequences adjacent to suspected or known methylated sequences. Methods of using primers having abasic regions or mismatches for identification of methylated sequences or sequences adjacent to suspected or known methylation sequences.
    Type: Application
    Filed: February 19, 2013
    Publication date: November 21, 2013
    Inventor: Anthony P. Shuber
  • PRIMERS FOR ANALYZING METHYLATED SEQUENCES AND METHODS OF USE THEREOF
    Publication number: 20130310550
    Abstract: Primers having abasic regions or mismatches for amplifying sequences suspected of having methylation. Primers having abasic regions or mismatches for amplifying sequences adjacent to suspected or known methylated sequences. Methods of using primers having abasic regions or mismatches for identification of methylated sequences or sequences adjacent to suspected or known methylation sequences.
    Type: Application
    Filed: February 19, 2013
    Publication date: November 21, 2013
    Inventor: Anthony P. Shuber
  • Compositions and methods for treating cancer
    Patent number: 8575124
    Abstract: This invention generally relates to compositions and methods for targeted delivery of chemotherapeutic agents to cancerous and pre-cancerous cells, thereby treating a cancer in a subject.
    Type: Grant
    Filed: February 18, 2011
    Date of Patent: November 5, 2013
    Inventor: Anthony P. Shuber
  • METHODS FOR DETECTING NUCLEIC ACIDS INDICATIVE OF CANCER
    Publication number: 20130280727
    Abstract: The invention provides methods for screening tissue or body fluid samples for nucleic acid indicia of cancer or precancer.
    Type: Application
    Filed: June 17, 2013
    Publication date: October 24, 2013
    Inventor: Anthony P. Shuber
  • DETECTION OF NUCLEIC ACIDS AND PROTEINS
    Publication number: 20130237433
    Abstract: The invention generally relates to methods for detecting a target nucleic acid and a target protein in a single assay.
    Type: Application
    Filed: April 23, 2013
    Publication date: September 12, 2013
    Inventor: Anthony P. Shuber
  • Detection of nucleic acids and proteins
    Patent number: 8530198
    Abstract: The invention generally relates to methods for detecting a target nucleic acid and a target protein in a single assay.
    Type: Grant
    Filed: February 1, 2011
    Date of Patent: September 10, 2013
    Assignee: Predictive Biosciences, Inc.
    Inventors: Anthony P. Shuber, Eugene Chiu
  • COMPOSITE ASSAY FOR DETECTING A CLINICAL CONDITION
    Publication number: 20130203058
    Abstract: The invention generally relates to methods for screening patients for one or more clinical conditions using a composite assay. According to certain aspects, methods of the invention involve isolating at least one nucleic acid from a biological sample obtained from the subject, detecting at least one sequence mutation and a chromosomal abnormality in the at least one nucleic acid in a single assay format, and identifying a clinical condition in said subject when both the sequence mutation and the chromosomal abnormality are present.
    Type: Application
    Filed: February 1, 2013
    Publication date: August 8, 2013
    Inventor: Anthony P. Shuber
  • METHODS FOR ASSESSING GENOMIC INSTABILITIES
    Publication number: 20130157875
    Abstract: The invention generally relates to methods for assessing a fetal abnormality.
    Type: Application
    Filed: January 14, 2013
    Publication date: June 20, 2013
    Inventor: Anthony P. Shuber
  • DETECTION OF CANCER
    Publication number: 20130122494
    Abstract: Assays for detecting and grading disease by assessing amounts of GSTP1 nucleic acid and ADAM protein in a sample, and methods of using the assays. In some embodiments, the assays use single molecule sequencing to simultaneously assay both GSTP1 nucleic acid and ADAM protein. The methods are especially useful for detecting and grading cancers, for example, prostate cancer.
    Type: Application
    Filed: May 15, 2012
    Publication date: May 16, 2013
    Applicant: PREDICTIVE BIOSCIENCES, INC.
    Inventors: Anthony P. Shuber, Cecilia A. Fernandez
  • METHODS FOR DETECTING MUTATIONS
    Publication number: 20130109576
    Abstract: The invention generally relates to methods for detecting mutations in a nucleic acid. In certain embodiments, the invention provides methods that involve forming a plurality of droplets, such that on average, each droplet includes a ratio of one nucleic acid template per bead, amplifying the template in the droplet to produce bead-bound amplicons, and sequencing at least one amplicon detect a mutation.
    Type: Application
    Filed: October 26, 2012
    Publication date: May 2, 2013
    Inventors: Anthony P. Shuber, Cecilia Fernandez
  • Detection of nucleic acids and proteins
    Patent number: 8431367
    Abstract: The invention generally relates to methods for detecting a target nucleic acid and a target protein in a single assay.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: April 30, 2013
    Assignee: Predictive Biosciences Corporation
    Inventor: Anthony P. Shuber
  • Methods for analysis of molecular events
    Patent number: 8409829
    Abstract: Methods and compositions are provided for detecting the presence of nucleic acid sequence variants in a subpopulation of nucleic acid molecules in a biological sample. These methods are particularly useful for identifying individuals with mutations indicative of cancer.
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: April 2, 2013
    Assignee: Esoterix Genetic Laboratories, LLC
    Inventors: Anthony P. Shuber, Lisa Kann, Duncan Whitney
  • Method for detecting a recombinant event
    Patent number: 8389220
    Abstract: Methods relating to isolating and amplifying chimeric nucleic acid molecules are provided. The methods of the invention are useful for detecting chromosome translocation events associated with diseases or conditions, such as cancer.
    Type: Grant
    Filed: July 18, 2011
    Date of Patent: March 5, 2013
    Assignee: Esoterix Genetic Laboratories, LLC
    Inventor: Anthony P. Shuber
  • Primers for analyzing methylated sequences and methods of use thereof
    Patent number: 8377657
    Abstract: Primers having abasic regions or mismatches for amplifying sequences suspected of having methylation. Primers having abasic regions or mismatches for amplifying sequences adjacent to suspected or known methylated sequences. Methods of using primers having abasic regions or mismatches for identification of methylated sequences or sequences adjacent to suspected or known methylation sequences.
    Type: Grant
    Filed: May 15, 2012
    Date of Patent: February 19, 2013
    Assignee: Predictive Biosciences Corporation
    Inventor: Anthony P. Shuber
  • METHODS FOR ASSESSING GENOMIC INSTABILITIES IN TUMORS
    Publication number: 20130023427
    Abstract: The invention generally relates to methods for assessing genomic instabilities in a tumor sample. The invention may further be used to predict grade, stage, and prognosis of cancer in a patient. The invention further relates to cataloging the efficacy of therapeutics on specific genomic instabilities and generating a personalized therapeutic regimen for a cancer patient based upon their genomic instabilities.
    Type: Application
    Filed: February 2, 2012
    Publication date: January 24, 2013
    Applicant: PREDICTIVE BIOSCIENCES INC.
    Inventors: Anthony P. Shuber, Thomas C. Meyers, Andy Hu