Abstract: The present invention relates to transgenic mice and isolated transgenic mouse cells, the mice and mouse cells comprising a disrupted H2 class I gene, a disrupted H2 class II gene, a functional HLA class I transgene, and a functional HLA class II transgene. In embodiments, the transgenic mouse or mouse cells are deficient for both H2 class I and class II molecules, wherein the transgenic mouse comprises a functional HLA class I transgene and a functional HLA class II transgene. In embodiments, the transgenic mouse or mouse cell has the genotype HLA-A2+HLA-DR1+?2m°IA?°. The invention also relates to methods of using a transgenic mouse of the invention.

Abstract: The present invention relates to transgenic mice and isolated transgenic mouse cells, the mice and mouse cells comprising a disrupted H2 class I gene, a disrupted H2 class II gene, a functional HLA class I transgene, and a functional HLA class II transgene. In embodiments, the transgenic mouse or mouse cells are deficient for both H2 class I and class II molecules, wherein the transgenic mouse comprises a functional HLA class I transgene and a functional HLA class II transgene. In embodiments, the transgenic mouse or mouse cell has the genotype HLA-A2+HLA-DR1+?2m°IA?°. The invention also relates to methods of using a transgenic mouse of the invention.

Abstract: The method for re-establishing the shielding of the cables of a strand on an electrical connector consists, over an annular part situated at one end connected to the connector, in removing only the outer insulating sheath of each shielded cable without stripping the cables of their electromagnetic shield, in grouping the shielded cables together into a strand and in surrounding the strand with an electrically conducting tape forming a sheath re-establishing the shielding of the strand, the sheath re-establishing the shielding being positioned in contact with the electromagnetic shield of the shielded cables and connected to the connector.

Abstract: The method for re-establishing the shielding of the cables of a strand on an electrical connector consists, over an annular part situated at one end connected to the connector, in removing only the outer insulating sheath of each shielded cable without stripping the cables of their electromagnetic shield, in grouping the shielded cables together into a strand and in surrounding the strand with an electrically conducting tape forming a sheath re-establishing the shielding of the strand, the sheath re-establishing the shielding being positioned in contact with the electromagnetic shield of the shielded cables and connected to the connector.

Abstract: The invention concerns a peptide comprising an epitope consisting of a sequence of amino acids selected among SEQ ID NO 1, SEQ ID NO 2, SEQ ID NO 3, and having a length not more than 24 amino acids.

Abstract: The present invention relates to transgenic mice and isolated transgenic mouse cells, the mice and mouse cells comprising a disrupted H2 class I gene, a disrupted H2 class II gene, a functional HLA class I transgene, and a functional HLA class II transgene. In embodiments, the transgenic mouse or mouse cells are deficient for both H2 class I and class II molecules, wherein the transgenic mouse comprises a functional HLA class I transgene and a functional HLA class II transgene. In embodiments, the transgenic mouse or mouse cell has the genotype HLA-A2+HLA-DR1+?2m°IA?°. The invention also relates to methods of using a transgenic mouse of the invention.

Abstract: The present invention-relates to transgenic mice and isolated transgenic mouse cells, the mice and mouse cells comprising a disrupted H2 class I gene, a disrupted H2 class II gene, a functional HLA class I transgene, and a functional HLA class II transgene. In embodiments, the transgenic mouse or mouse cells are deficient for both H2 class I and class II molecules, wherein the transgenic mouse comprises a functional HLA class I transgene and a functional HLA class II transgene. In embodiments, the transgenic mouse or mouse cell has the genotype HLA-A2+HLA-DR1+?2m°IA?°. The invention also relates to methods of using a transgenic mouse of the invention.

Abstract: The invention relates to the use of an expression vector construction coding for the functional HLA-DPal03?401 complex specifically identified by anti-HLA-DP antibodies, in order to create transgenic mice. The invention also relates to the use of the transgenic mice obtained, such as for the comparative preclinical study of the efficacy of vaccine candidates in order to asses the risks associated with the unwanted induction of an autoimmune disease and in order to determine a therapeutic strategy.

Abstract: The invention relates to a composite yarn including a filament yarn of an inorganic or organic material and a matrix of polymer material, the filament yarn being coated, extruded, or incorporated in the polymer material matrix. The matrix includes at least one foamed polymer. A composite yarn is characterized in that it has a core of an above-mentioned composite yarn and is coated, extruded or incorporated in a second polymer material matrix surrounding the core. Various methods may be used for producing the inventive yarns by coating and extrusion.

Abstract: The present invention relates to transgenic mice and isolated transgenic mouse cells, the mice and mouse cells comprising a disrupted H2 class I gene, a disrupted H2 class II gene, a functional HLA class I transgene, and a functional HLA class II transgene. In embodiments, the transgenic mouse or mouse cells are deficient for both H2 class I and class II molecules, wherein the transgenic mouse comprises a functional HLA class I transgene and a functional HLA class II transgene. In embodiments, the transgenic mouse or mouse cell has the genotype HLA-A2+HLA-DR1+?2m°IA?°. The invention also relates to methods of using a transgenic mouse of the invention.

Abstract: The invention relates to a composite yarn including a filament yarn of an inorganic or organic material and a matrix of polymer material, the filament yarn being coated, extruded, or incorporated in the polymer material matrix. The matrix includes at least one foamed polymer. A composite yarn is characterized in that it has a core of an above-mentioned composite yarn and is coated, extruded or incorporated in a second polymer material matrix surrounding the core. Various methods may be used for producing the inventive yarns by coating and extrusion.

Abstract: The present invention relates to transgenic mice and isolated transgenic mouse cells, the mice and mouse cells comprising a disrupted H2 class I gene, a disrupted H2 class II gene, a functional HLA class I transgene, and a functional HLA class II transgene. In embodiments, the transgenic mouse or mouse cells are deficient for both H2 class I and class II molecules, wherein the transgenic mouse comprises a functional HLA class I transgene and a functional HLA class II transgene. In embodiments, the transgenic mouse or mouse cell has the genotype HLA-A2+HLA-DR1+?2m°IA?°. The invention also relates to methods of using a transgenic mouse of the invention.