Abstract: Pre-plating systems and related methods are disclosed. A pre-plating system includes a press, an infeed robot configured to deliver a structural member to the press, and an outfeed robot configured to remove the structural member from the press. The press is configured to secure a plate to the structural member while the structural member is held in position by at least one of the infeed robot or the outfeed robot. A pre-plating system includes a press, a transfer pedestal, a plate picking robot, and a press loading robot. The plate picking robot is configured to pick a plate from a container and position the plate on the transfer pedestal. The press loading robot is configured to transfer the plate to the press. The press is configured to press the plate into a structural member positioned within the press.

Abstract: A method for determining an edge profile of a custom decorative article to be installed in an installation area is disclosed, the installation area having a perimeter having a plurality of corners. A computing device receives data indicative of a plurality of coordinates corresponding to the plurality of corners of the perimeter of the installation area. Based on at least first, second, and third coordinates respectively corresponding to first, second, and third corners of the plurality of corners of the perimeter of the installation area, the computing device determines dimensional and/or geometric characteristics of a pair of opposed portions of the edge profile that, in an installed position, are configured to meet to form a corner of the custom decorative article when installed at the second corner of the perimeter of the installation area.

Abstract: A method for determining an edge profile of a custom decorative article to be installed in an installation area is disclosed, the installation area having a perimeter having a plurality of corners. A computing device receives data indicative of a plurality of coordinates corresponding to the plurality of corners of the perimeter of the installation area. Based on at least first, second, and third coordinates respectively corresponding to first, second, and third corners of the plurality of corners of the perimeter of the installation area, the computing device determines dimensional and/or geometric characteristics of a pair of opposed portions of the edge profile that, in an installed position, are configured to meet to form a corner of the custom decorative article when installed at the second corner of the perimeter of the installation area.

Abstract: Provided is a food composition which include a myceliated high-protein food product and methods to make such compositions, which are mixtures of myceliated high-protein food products and other edible materials. A food composition includes dairy alternative products, ready to mix beverages and beverage bases; extruded and extruded/puffed products; sheeted baked goods; meat analogs and extenders; baked goods and baking mixes; granola; and soups/soup bases. Food compositions also include texturized plant protein which can be used for making meat-structured plant protein meat analog or meat extender products. The food compositions have reduced undesirable flavors and reduced undesirable aromas due to use of myceliated high-protein food products as compared to use of similar high-protein material that is not myceliated.

Abstract: It is disclosed herein that ssAAV and scAAV vectors of the same serotype administered by injection into the cerebrospinal fluid (CSF) via the intracerebroventricular (ICV) or intrathecal (cisternal or lumbar) route exhibit different cellular tropisms in the central nervous system. Thus, a subject can be treated by injection into the CSF of ssAAV or scAAV vector encoding a therapeutic protein, such as an ssAAV9 or scAAV9 vector. The therapeutic protein can be targeted to specific cells using these vectors. In some embodiments, scAAV9 is utilized to achieve superior transduction in the hippocampus, cerebellum and cerebral cortex where both neurons, particularly Purkinje neurons, and glial cells (such as astrocytes) are transduced. In other embodiments, ssAAV9 is utilized to minimize transduction of astrocytes. In further embodiments, an immunosuppressive agent is also administered to the subject.

Abstract: An insert for an arthropod trapping device. The insert comprising a substrate and a frame for supporting the substrate, where a surface of the substrate has an adhesive disposed thereon, an optional mounting bracket spaced apart from the adhesive surface of the insert and located at a first end of the insert, and an optional graspable tab extending from the frame at a second end of the insert.

Abstract: The present invention relates to a sensitizer-peptide conjugate for use in the treatment of cancer. In particular, the present invention relates to a sensitizer-peptide conjugate for use in the treatment of melanoma. The use of such sensitizer-peptide conjugate in photodynamic therapy or sonodynamic therapy is also disclosed. According to the present invention, there is provided a sensitizer-peptide conjugate for use in the treatment of cancer; wherein the sensitizer-peptide conjugate comprises at least one sensitizer and at least one peptide.

Abstract: The present invention provides an assembly having a wheelchair and a wheelchair rigging receptacle. The wheelchair may include an appendage support rigging that is releasably affixed to the frame and configured to support a user's appendage, e.g. foot, when in use. The assembly also provides at least one receptacle configured to retain the appendage support rigging within, when the appendage support rigging is not affixed to the frame. The receptacle may comprise two opposing flexible side walls, a rear wall extending between the side walls, and a bottom extending between a lower edge of the walls to define an interior cavity between an inner surface of the wall and the base that has a width approximately equal to a width of the appendage support rigging. The receptacle also includes at least one mounting device to affix the receptacle to the anti-tip bar of the wheelchair at the rear of the seating surface.

Abstract: The present invention relates to a sensitizer-peptide conjugate for use in the treatment of cancer. In particular, the present invention relates to a sensitizer-peptide conjugate for use in the treatment of melanoma. The use of such sensitizer-peptide conjugate in photodynamic therapy or sonodynamic therapy is also disclosed. According to the present invention, there is provided a sensitizer-peptide conjugate for use in the treatment of cancer; wherein the sensitizer-peptide conjugate comprises at least one sensitizer and at least one peptide.

Abstract: A minicomputer (1) comprises a computer monitor (2) configured from a computer monitor (3) by mounting a microcomputer device (25) and a power supply (35) for powering the microcomputer device (25) on a component tray (10) secured to a screen support housing (7) of the computer monitor (3). The microcomputer device (25) comprises a microcomputer board sold under the trade name Raspberry Pi. The microcomputer device (25) is configured to communicate wirelessly with a remote computer with a keyboard (4) and with a mouse (5), and to control a visual display screen (6) of the computer monitor (2) through a screen controller (18), also located on the component tray (10). A card receiving slot (39) of the microcomputer device (25) is accessed through a card accommodating opening (38) formed in the component tray (10) and through a card access opening (42) formed in a rear wall (12) of a rear housing (8) of the computer monitor (3).

Abstract: An apparatus for finishing a component includes at least one articulating arm, at least one plasma gun disposed at an end of a first articulating arm of the at least one articulating arm, at least one shot peen nozzle maintained in a fixed positioned relative to the plasma gun, and a controller controllably coupled to the articulating arm such that output signals from the controller control motions of the articulating arm.

Abstract: A method of fabricating process-equivalent test specimens to an additively manufactured component includes generating a processing history model of a component, dividing the component into regions based on input data variations in processing history, wherein each region is characterized by an identified range of input data, determining additive manufacturing processing parameters needed to additively manufacture one or more test specimens that each mimic the processing history in one of the regions, and fabricating the one or more test specimens using the processing parameters determined.

Abstract: The present invention relates to a sensitizer-peptide conjugate for use in the treatment of cancer. In particular, the present invention relates to a sensitizer-peptide conjugate for use in the treatment of melanoma. The use of such sensitizer-peptide conjugate in photodynamic therapy or sonodynamic therapy is also disclosed. According to the present invention, there is provided a sensitizer-peptide conjugate for use in the treatment of cancer; wherein the sensitizer-peptide conjugate comprises at least one sensitizer and at least one peptide.

Abstract: An apparatus for finishing a component includes at least one articulating arm, at least one plasma gun disposed at an end of a first articulating arm of the at least one articulating arm, at least one shot peen nozzle maintained in a fixed positioned relative to the plasma gun, and a controller controllably coupled to the articulating arm such that output signals from the controller control motions of the articulating arm.

Abstract: An apparatus for finishing a component includes at least one articulating arm, at least one plasma gun disposed at an end of a first articulating arm of the at least one articulating arm, at least one shot peen nozzle maintained in a fixed positioned relative to the plasma gun, and a controller controllably coupled to the articulating arm such that output signals from the controller control motions of the articulating arm.

Abstract: An apparatus for finishing a component includes at least one articulating arm having a shot peening apparatus and at least one laser source. A plurality of laser redirectors are configured to redirect a laser originating from the laser source. Each laser redirector in the plurality of laser redirectors is mounted to a first rail and a second rail. A controller is controllably coupled to the articulating arm and each of the rails such that output signals from the controller control a position of the articulating arm, and a position of each laser redirector in the plurality of laser redirectors.

Abstract: A ratcheting inserter device for tensioning a knotless suture anchor includes an outer inserter shaft and an inner inserter shaft having a common longitudinal axis. A ratcheting mechanism provided between the inner inserter shaft and the outer inserter shaft permits rotation of the inner inserter shaft in one direction relative to the outer inserter shaft. The outer inserter shaft has a protrusion at a distal end that is received by an anchor outer sleeve of a suture anchor to prevent relative rotation thereof, and the inner inserter shaft has a projection at the distal end that is received by an inner core of the anchor for rotational movement therewith. The ratcheting inserter device rotates the inner core of the suture anchor to spool and tension suture thread. Thereafter, the ratcheting mechanism is disengaged and the inner inserter shaft is forced axially into the anchor outer sleeve.

Abstract: The present invention provides an assembly having a wheelchair and a wheelchair rigging receptacle. The wheelchair may include an appendage support rigging that is releasably affixed to the frame and configured to support a user's appendage, e.g. foot, when in use. The assembly also provides at least one receptacle configured to retain the appendage support rigging within, when the appendage support rigging is not affixed to the frame. The receptacle may comprise two opposing flexible side walls, a rear wall extending between the side walls, and a bottom extending between a lower edge of the walls to define an interior cavity between an inner surface of the wall and the base that has a width approximately equal to a width of the appendage support rigging. The receptacle also includes at least one mounting device to affix the receptacle to the anti-tip bar of the wheelchair at the rear of the seating surface.