Patents by Inventor Anthony Schmitt
Anthony Schmitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11873481Abstract: Provided herein are methods and compositions for preparing nucleic acid templates wherein spatial-proximal and molecular contiguity of target nucleic acids is preserved, and the sequencing data obtained therefrom is used, but not limited to, identification of genomic variants, determination of contiguity information to inform assemblies of target nucleic acids de novo including deconvolution of haplotype phase information, and analyses of conformation and topology of target nucleic acids.Type: GrantFiled: November 20, 2018Date of Patent: January 16, 2024Assignee: Arima Genomics, Inc.Inventors: Siddarth Selvaraj, Anthony Schmitt, Bret Reid
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Publication number: 20220281906Abstract: Provided herein are methods and compositions for preparing nucleic acids in samples that preserve spatial-proximal contiguity information. Samples include, but are not limited to, formalin-fixed paraffin-embedded (FFPE) samples, deeply formalin-fixed samples and samples that comprise protein:cfDNA complexes.Type: ApplicationFiled: May 26, 2022Publication date: September 8, 2022Inventors: Anthony SCHMITT, Catherine TAN, Derek REID, Chris DE LA TORRE, Siddarth SELVARAJ
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Publication number: 20220205017Abstract: Provided herein are methods and compositions for preparing sequencing templates that provide uniform genome coverage and preserve spatial-proximal contiguity information.Type: ApplicationFiled: May 19, 2020Publication date: June 30, 2022Inventors: Anthony SCHMITT, Siddarth SELVARAJ, Bret REID, Stephen MAC, Xiang ZHOU
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Patent number: 11370810Abstract: Provided herein are methods and compositions for preparing nucleic acids in samples that preserve spatial-proximal contiguity information. Samples include, but are not limited to, formalin-fixed paraffin-embedded (FFPE) samples, deeply formalin-fixed samples and samples that comprise protein:cfDNA complexes.Type: GrantFiled: November 19, 2019Date of Patent: June 28, 2022Assignee: ARIMA GENOMICS, INC.Inventors: Anthony Schmitt, Catherine Tan, Derek Reid, Chris De La Torre, Siddarth Selvaraj
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Publication number: 20220177961Abstract: The present invention relates to methods for haplotype determination and, in particular, haplotype determination at the whole genome level as well as targeted haplotype determination.Type: ApplicationFiled: October 18, 2021Publication date: June 9, 2022Applicant: Ludwig Institute for Cancer Research LtdInventors: Bing Ren, Siddarth Selvaraj, Jesse Dixon, Anthony Schmitt
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Publication number: 20210363516Abstract: Provided herein are methods and compositions for preparing nucleic acid templates wherein spatial-proximal and molecular contiguity of target nucleic acids is preserved, and the sequencing data obtained therefrom is used, but not limited to, identification of genomic variants, determination of contiguity information to inform assemblies of target nucleic acids de novo including deconvolution of haplotype phase information, and analyses of conformation and topology of target nucleic acids.Type: ApplicationFiled: November 20, 2018Publication date: November 25, 2021Inventors: Siddarth SELVARAJ, Anthony SCHMITT, Bret REID
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Patent number: 11149311Abstract: The present invention relates to methods for haplotype determination and, in particular, haplotype determination at the whole genome level as well as targeted haplotype determination.Type: GrantFiled: October 24, 2019Date of Patent: October 19, 2021Assignee: Ludwig Institute for Cancer Research LtdInventors: Bing Ren, Siddarth Selvaraj, Jesse Dixon, Anthony Schmitt
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Publication number: 20200199670Abstract: The present invention relates to methods for haplotype determination and, in particular, haplotype determination at the whole genome level as well as targeted haplotype determination.Type: ApplicationFiled: October 24, 2019Publication date: June 25, 2020Inventors: Bing Ren, Siddarth Selvaraj, Jesse Dixon, Anthony Schmitt
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Publication number: 20200157130Abstract: Provided herein are methods and compositions for preparing nucleic acids in samples that preserve spatial-proximal contiguity information. Samples include, but are not limited to, formalin-fixed paraffin-embedded (FFPE) samples, deeply formalin-fixed samples and samples that comprise protein:cfDNA complexes.Type: ApplicationFiled: November 19, 2019Publication date: May 21, 2020Inventors: Anthony SCHMITT, Catherine TAN, Derek REID, Chris DE LA TORRE, Siddarth SELVARAJ
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Patent number: 10508303Abstract: The present invention relates to methods for haplotype determination and, m particular, haplotype determination at the whole genome level as well as targeted haplotype determination.Type: GrantFiled: July 18, 2014Date of Patent: December 17, 2019Assignee: LUDWIG INSTITUTE FOR CANCER RESEARCH LTDInventors: Bing Ren, Siddarth Selvaraj, Jesse Dixon, Anthony Schmitt
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Patent number: 7965654Abstract: A system and computer-readable medium for designing a network are disclosed. A network is designed by a system having modules configured to perform steps that generate the network wherein nodes originate and terminate traffic to keep delay related to node-to-node delay-sensitive communication below a threshold. The computer-readable medium stores instructions for controlling a computing device to design the network. The instructions comprise obtaining an initial network topology including links and traffic routing based on a volume of traffic, allocating a maximum delay to each link in the network topology in proportion to a square root of an imputed cost for each of the links, sizing a bandwidth required for each of the links based on a current traffic routing and at least one of a maximum delay allocated to the link, determining link lengths and rerouting traffic according to shortest paths with respect to the determined link lengths.Type: GrantFiled: November 30, 2009Date of Patent: June 21, 2011Assignee: AT&T Intellectual Property II, L.P.Inventors: John Gregory Klincewicz, James Anthony Schmitt, Richard Tekee Wong
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Publication number: 20100074115Abstract: A system and computer-readable medium for designing a network are disclosed. A network is designed by a system having modules configured to perform steps that generate the network wherein nodes originate and terminate traffic to keep delay related to node-to-node delay-sensitive communication below a threshold. The computer-readable medium stores instructions for controlling a computing device to design the network. The instructions comprise obtaining an initial network topology including links and traffic routing based on a volume of traffic, allocating a maximum delay to each link in the network topology in proportion to a square root of an imputed cost for each of the links, sizing a bandwidth required for each of the links based on a current traffic routing and at least one of a maximum delay allocated to the link, determining link lengths and rerouting traffic according to shortest paths with respect to the determined link lengths.Type: ApplicationFiled: November 30, 2009Publication date: March 25, 2010Applicant: AT&T Corp.Inventors: John Gregory KLINCEWICZ, James Anthony SCHMITT, Richard Tekee WONG
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Patent number: 7626945Abstract: A system and computer-readable medium for designing a network are disclosed. A network is designed by a system having modules configured to perform steps that generate the network wherein nodes originate and terminate traffic to keep delay related to node-to-node delay-sensitive communication below a threshold. The computer-readable medium stores instructions for controlling a computing device to design the network. The instructions comprise obtaining an initial network topology including links and traffic routing based on a volume of traffic, allocating a maximum delay to each link in the network topology in proportion to a square root of an imputed cost for each of the links, sizing a bandwidth required for each of the links based on a current traffic routing and at least one of a maximum delay allocated to the link, determining link lengths and rerouting traffic according to shortest paths with respect to the determined link lengths.Type: GrantFiled: July 20, 2005Date of Patent: December 1, 2009Assignee: AT&T Intellectual Property II, L.P.Inventors: John Gregory Klincewicz, James Anthony Schmitt, Richard Tekee Wong
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Publication number: 20050223636Abstract: The invention described herein includes a biodegradable weaning mat comprising a biodegradable main body.Type: ApplicationFiled: March 28, 2005Publication date: October 13, 2005Inventors: Anthony Schmitt, Darryl Metcalfe
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Patent number: 6934259Abstract: An apparatus and method for designing a network are disclosed. The network is designed wherein nodes originate and terminate traffic to keep delay related to node-to-node delay-sensitive communication below a specified threshold. The method obtains an initial network topology including links and traffic routing based on a volume of traffic, allocates a maximum delay to each link in the network topology in proportion to the square root of an imputed cost for each link, sizes a bandwidth required for each link based on a current traffic routing and at least one of a maximum delay allocated to the link, determines link lengths and reroutes traffic according to shortest paths with respect to the determined link lengths.Type: GrantFiled: November 12, 2003Date of Patent: August 23, 2005Assignee: AT&T CorpInventors: John Gregory Klincewicz, James Anthony Schmitt, Richard Tekee Wong
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Publication number: 20040095887Abstract: An apparatus and method for designing a network are disclosed. The network is designed wherein nodes originate and terminate traffic to keep delay related to node-to-node delay-sensitive communication below a specified threshold. The method obtains an initial network topology including links and traffic routing based on a volume of traffic, allocates a maximum delay to each link in the network topology in proportion to the square root of an imputed cost for each link, sizes a bandwidth required for each link based on a current traffic routing and at least one of a maximum delay allocated to the link, determines link lengths and reroutes traffic according to shortest paths with respect to the determined link lengths.Type: ApplicationFiled: November 12, 2003Publication date: May 20, 2004Applicant: AT&T Corp.Inventors: John Gregory Klincewicz, James Anthony Schmitt, Richard Tekee Wong
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Patent number: 6697334Abstract: A method and apparatus for designing a network that supports an integrated environment for all types of applications while satisfying individual performance requirements. An initial network topology is retrieved or created, including links and traffic routing based on a volume of traffic. A maximum delay is then allocated to each link in the network topology so that the delay limits on node-to-node communication are satisfied. Further, a bandwidth required for each link is sized based on a current traffic routing as well as a maximum delay allocated to the link and total link utilization. Link lengths are then determined, based on marginal costs, and traffic is rerouted according to shortest paths with respect to the link lengths.Type: GrantFiled: January 18, 2000Date of Patent: February 24, 2004Assignee: AT&T Corp.Inventors: John Gregory Klincewicz, James Anthony Schmitt, Richard Tekee Wong
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Patent number: 6498778Abstract: A method and system are provided for computing an optimal restoration capacity and/or optimal restoration paths for a network to resolve a restoration scenario by solving a linear program (LP) model. The LP model includes decision variables corresponding to restoration capacity and restoration paths and constraints requiring restoration of traffic and conservation of capacity in the network. For example, the system determines a set of network paths that need to be restored in the network, preprocesses network data corresponding to the network to reduce LP processing workload and time; generates possible restoration paths and solves the LP model, preferably through column generation methods, to determine the optimal restoration capacity and/or the optimal restoration paths to resolve the restoration scenario; changes the LP solution into integer form, as necessary, and changes the LP solution in integer form to the original format of the network data or an equivalent thereof.Type: GrantFiled: December 17, 1998Date of Patent: December 24, 2002Assignee: AT&T Corp.Inventors: Sebastian Cwilich, Mei Deng, David James Houck, Jr., David Frederick Lynch, James Anthony Schmitt, Luiz Antonio Vitoria, Ken Ambs, Dicky Chi Kwong Yan