Patents by Inventor Anton Jan van Zonneveld

Anton Jan van Zonneveld has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITION OF POLYOMAVIRUS REPLICATION
    Publication number: 20230212580
    Abstract: The invention relates to antisense molecules and methods for modulating splicing of polyomavirus T antigen pre-mRNA. In one aspect the invention relates to an antisense oligonucleotide 12 to 30, preferably 17, 18, 19 or 20 to 30 nucleobases in length which comprises a sequence that is the reverse complement of a contiguous stretch of at least 12 nucleobases of a polyomavirus T-antigen pre-mRNA and which antisense oligonucleotide can modulate splicing of said T-antigen pre-mRNA in a cell.
    Type: Application
    Filed: June 22, 2022
    Publication date: July 6, 2023
    Inventors: Eric Peter VAN DER VEER, Anton Jan VAN ZONNEVELD, Jurriën PRINS
  • Inhibition of polyomavirus replication
    Patent number: 11661602
    Abstract: The invention relates to antisense molecules and methods for modulating splicing of polyomavirus T antigen pre-mRNA. In one aspect the invention relates to an antisense oligonucleotide 12 to 30, preferably 17, 18, 19 or 20 to 30 nucleobases in length which comprises a sequence that is the reverse complement of a contiguous stretch of at least 12 nucleobases of a polyomavirus T-antigen pre-mRNA and which antisense oligonucleotide can modulate splicing of said T-antigen pre-mRNA in a cell.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: May 30, 2023
    Assignee: ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC
    Inventors: Eric Peter Van Der Veer, Anton Jan Van Zonneveld, Jurriën Prins
  • INHIBITION OF POLYOMAVIRUS REPLICATION
    Publication number: 20210010004
    Abstract: The invention relates to antisense molecules and methods for modulating splicing of polyomavirus T antigen pre-mRNA. In one aspect the invention relates to an antisense oligonucleotide 12 to 30, preferably 17, 18, 19 or 20 to 30 nucleobases in length which comprises a sequence that is the reverse complement of a contiguous stretch of at least 12 nucleobases of a polyomavirus T-antigen pre-mRNA and which antisense oligonucleotide can modulate splicing of said T-antigen pre-mRNA in a cell.
    Type: Application
    Filed: March 1, 2019
    Publication date: January 14, 2021
    Inventors: Eric Peter VAN DER VEER, Anton Jan VAN ZONNEVELD, Jurriën PRINS
  • DIAGNOSTIC PORTFOLIO AND ITS USES
    Publication number: 20150152499
    Abstract: A diagnostic portfolio comprising or consisting of isolated nucleic acid molecules, their complement and/or fragments thereof, said nucleic acid molecules, complements, equivalents and/or fragments thereof being represented by sequences comprising or consisting of sequences having at least 80% of sequence identity with SEQ ID NO:1-92, or 49-140 or derived thereof (i.e. groups a), b), c), d), e), f), g), h), i) or j) or subgroups thereof) and their uses.
    Type: Application
    Filed: July 3, 2013
    Publication date: June 4, 2015
    Applicant: InteRNA Technologies B.V.
    Inventors: Anton Jan Van Zonneveld, Jacques Duijs, Johan Kuiper, Thijs Jan Zweers, Johan Wouter Jukema, Eugene Berezikov
  • Gene therapy to promote angiogenesis
    Publication number: 20030031649
    Abstract: A nucleic acid delivery vehicle for enhancing and/or inducing angiogenesis. This nucleic acid delivery vehicle includes a nucleic acid having at least one sequence coding for a protein capable of increasing nitric oxide production and a nucleic acid delivery carrier. The vehicle can be used in a method for enhancing and/or inducing angiogenesis in an individual involving providing cells of the individual with the nucleic acid delivery vehicle. Also disclosed is a cell for producing the nucleic acid delivery vehicle for enhancing and/or inducing angiogenesis.
    Type: Application
    Filed: May 1, 2002
    Publication date: February 13, 2003
    Inventors: Anton Jan van Zonneveld, Stefan Frederik Franciscus Verlinden
  • Methods of gene therapy with a DNA sequence encoding NOS
    Patent number: 6447768
    Abstract: A nucleic acid delivery vehicle for enhancing and/or inducing angiogenesis. This nucleic acid delivery vehicle includes a nucleic acid having at least one sequence coding for a protein capable of increasing nitric oxide production, and further includes a nucleic acid delivery carrier. The vehicle can be used in a method for enhancing and/or inducing angiogenesis in an individual which involves providing cells of the individual with the nucleic acid delivery vehicle. Also disclosed is a cell for producing the nucleic acid delivery vehicle for enhancing and/or inducing angiogenesis.
    Type: Grant
    Filed: December 29, 1999
    Date of Patent: September 10, 2002
    Assignee: Introgene B.V.
    Inventors: Anton Jan van Zonneveld, Stefan Frederik Franciscus Verlingen