Abstract: A specimen holder (10) is proposed in order to create a capability for preparing, in a cutting device, in particular a microtome or ultramicrotome, a specimen that is to examined in an AFM. The specimen holder (10) is embodied in several parts. It comprises an insert (12) in which the specimen is secured. Also provided is a receiving ring (14) in which the insert (12) can be received. The insert together with the receiving ring (14) is mounted, in particular thread-joined, on a base element (16). As a result of the mounting of the receiving ring (14) on the base element (16), the insert together with the specimen is fixed in its position.

Abstract: The microtome or ultramicrotome comprises a knife (7) and a specimen arm (3) movable relative to the knife (7). At least one light source for illuminating a region around the preparation (5) is also provided. The at least one light source comprises at least one light-emitting diode (31, 41, 51).

Abstract: An apparatus (1) for handling coverslips (20) for specimen slides (9) comprises a transport arm (8), a base block (3) mounted on the transport arm and having a having a notional center axis (3a), and at least two suction devices (4 and 5) carried by the base block (3), each suction device (4 and 5) having an end (4a and 5a) that comes into contact with a coverslip (2) and points away from the notional center axis (3a) of said base block (3). The base block (3) both removes a single coverslip (2) from a magazine (24), and deposits the removed coverslip (2) onto a specimen slide (9).

Abstract: A system for staining and coverslipping specimen slides, having a stainer (1) and a coverslipper (3) that are arranged next to one another. A transfer device (2), which transports racks with specimen slides from the stainer (1) to the coverslipper (3), is provided between the stainer (1) and the coverslipper (3). Transport is automated so that operation by the user is substantially reduced.

Abstract: A specimen holder for freezing water-containing preparations under high pressure is disclosed. The specimen holder possesses a housing sheath in which a cutout is provided. A specimen retention element is arranged in the cutout of the specimen holder, and can be sprayed with a coolant, from both sides, through the cutout. The specimen retention element is made up of at least a first part and a second part, a recess for holding the specimen is shaped in the second part. The second part is pressed with a screw against the first part in such a way that the recess is sealed in pressure-tight fashion. Also disclosed are a method and system for freezing water-bearing specimens under high pressure.

Abstract: A container (2) for tissue preparation for the tissue embedding, having a base body (4), that is formed out cylindrical shaped side wall (5), a floor (6) and several bridges (50). The bridges (50) subdivide the container (2) in several sub-containers (52). The side wall (5) has a plurality of slit shaped openings (12), that extend essentially over the total height of the side wall (5).

Abstract: A specimen holder for freezing water-containing preparations under high pressure is disclosed. The specimen holder possesses a housing sheath in which a cutout is provided. A specimen retention element is arranged in the cutout of the specimen holder, and can be sprayed with a coolant, from both sides, through the cutout. The specimen retention element is made up of at least a first part and a second part, a recess for holding the specimen is shaped in the second part. The second part is pressed with a screw against the first part in such a way that the recess is sealed in pressure-tight fashion. Also disclosed are a method and system for freezing water-bearing specimens under high pressure.

Abstract: A device for forming two triangular glass knives from a glass square, such as for ultramicrotomy, has a rotary table and a holding device for receiving, aligning, and fixing the glass square to be broken positioned on the rotary table. The holding device has two opposingly arranged clamping jaws of U-shaped profile for holding the glass square therebetween arranged on the rotary table. The rotary table's axis of rotation is aligned with the center of the glass square held between the clamping jaws. A scoring and breaking device is positioned above the table alignable with the glass square.

Abstract: The invention relates to a microtome having a blade oscillating transverse to the direction of advancing the cut, for sections on soft tissue samples. The oscillation frequency of the blade is controlled variably by the rotational speed of an electric motor. At the same time, the oscillation amplitude of the blade is also adjustable variably with the aid of an adjustable eccentric or a displacement device. This makes individual adjustment to the consistency of the tissue sample possible, which leads to improved quality of the microtome sections, in particular to a reduction in the waviness of the sections. This makes significantly thinner microtome sections possible, with corresponding advantages during microscopy.

Abstract: Device for dehydrating and/or embedding preferably frozen samples, comprising a Dewar vessel (1) filled with liquid nitrogen (2) and a metallic element (4), anchored to the floor (3), of material of good thermal conductivity, which exhibits at its upper end in the region of attachment of the Dewar neck a cover (5) with a metallic cooling surface (6, 7) which corresponds with the complementarily designed lower contact surfaces of the thermostatically heated (9, 10) substitution (PLT) containers (8) or respectively of the lower part of a freeze-drying chamber in a manner which ensures a good heat transfer between the corresponding surfaces.

Abstract: A microtome, or an ultramicrotome having the specimen arm operating through an opening in the cryo chamber wall in a manner substantially free of the mechanical influence of a conventional seal is disclosed. An elongated slot permits movement of the specimen arm while minimizing the clearance between the sides of the arm and chamber wall reduces loss. Inner and outer baffles can be used to further reduce loss.