Patents by Inventor Antonia Jekkel nee Bokany

Antonia Jekkel nee Bokany has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microbial process for the production of immunosuppressive antibiotics
    Patent number: 5156960
    Abstract: The invention relates to a microbial process for the production of immunosuppressive cyclosporine antibiotic complex or of its components, cyclosporine A, cyclosporine B and cyclosporine C, by the aerobic fermentation of a filamentous fungus strain biosynthesizing the above antibiotic(s) in a nutrient medium containing utilizable carbon and nitrogen sources as well as mineral salts, and by isolating the products formed, which comprises culturing a strain of the novel Tolypocladium varium fungus species producing the cyclosporine antibiotic complex, preferably tolypocladium varium sp. nov. CY/93, deposited at the National Collection of Agricultural and Industrial Microorganisms, Budapest, Hungary under the number NCAIM(P)F 001005, on a nutrient medium containing carbon sources, organic and inorganic nitrogen sources as well as mineral salts, under aerobic conditions, at 25.degree. to 30.degree. C., and, if desired, isolating and purifying the cyclosporine antibiotic complex or its components produced.
    Type: Grant
    Filed: December 20, 1989
    Date of Patent: October 20, 1992
    Assignee: Biogal Gyogyszergyar
    Inventors: Antonia Jekkel nee Bokany, Gabor Ambrus, Eva Toth-Sarudy, Istvan Mihaly, Agota Hulber nee Dobos, Attila Andor, Karoly Albrecht, Kalman Konczol, Valeria Szell, Eva Tomori nee Joszt, Imre Moravcsik, Kalman Polya, Janos Erdei, Lajos Kiss, Bela Makadi, Karoly Nagy, Bela Palotas, Etelka Deli nee Konszky, Karoly Buzasi, Aniko Molnar nee Antal, Gyorgy Santha, Vilma Szaszhegyesi
  • Microbiological process for preparing 9.alpha.-hydroxy-4-androstene-3,17-dione
    Patent number: 5004695
    Abstract: The invention relates to a process for the production of 9.alpha.-hydroxy-4-androstene-3,17-dione from natural sterols of plant or animal origin or from mixtures thereof by the submerged aerobic fermentation of an enzyme-deficient, sterol-de-grading microorganism in a nutrient medium containing utilizable carbon and nitrogen sources as well as mineral salts, and by isolating the product formed, which comprises transforming the sterol or sterol mixture with the culture of a 1,2-steroid-dehydrogenase deficient strain of new Mycobacterium roseum species which is able to degrade the side-chain of natural sterols, preferably with Mycobacterium roseum sp. nov. 1108/1 deposited at the National Collection of Agricultural and Industrial Microorganisms, Budapest, Hungary under the number NCAIM B (P) 000339, and by isolating and purifying the 9.alpha.-hydroxy-4-androstene-3,17-dione obtained.
    Type: Grant
    Filed: November 5, 1987
    Date of Patent: April 2, 1991
    Assignee: Richter Gedeon Vegyeszeti Gyar R.T.
    Inventors: Antonia Jekkel nee Bokany, Karoly Albrecht, Gabor Ambrus, Tibor Lang, Istvan M. Szabo, Eva Ilkoy, Kalman Konczol, Imre Moravcsik, Gabor Hantos, Emilia Simonovits, Zsuzsanna Lengyel nee Szemenyei, Zsuzesanna Vida, Eva Csajagi
  • Method for the preparation of antibiotic sisomicin
    Patent number: 4365020
    Abstract: A process of producing sisomycin by cultivating a new species of Micromonospora.
    Type: Grant
    Filed: December 8, 1980
    Date of Patent: December 21, 1982
    Assignee: CHINOIN Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Istvan Gado, Antonia Jekkel nee Bokany, Gyorgy Szvoboda, Miklos Jarai, Sandor Piukovich, Sandor Istvan
  • Micromonospora culture
    Patent number: 4363876
    Abstract: A culture of Micromonospora rosea capable of producing the antibiotic sisomicin.
    Type: Grant
    Filed: January 30, 1980
    Date of Patent: December 14, 1982
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Istvan Gado, Antonia Jekkel nee Bokany, Gy uml/o/ rgy Szvoboda, Miklos Jarai, Sandor Piukovich, Sandor Istvan