Patents by Inventor Antonio A. Albano

Antonio A. Albano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITION
    Publication number: 20200330600
    Abstract: The present invention relates to a pharmaceutical composition comprising a solid dispersion of a drug. In the composition, the drug is in substantially amorphous form.
    Type: Application
    Filed: November 25, 2019
    Publication date: October 22, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Antonio ALBANO, Dipen DESAI, James DiNUNZIO, Zenaida GO, Raman Mahadevan IYER, Harpreet K. SANDHU, Navnit Hargovindas SHAH
  • PHARMACEUTICAL COMPOSITION
    Publication number: 20180369388
    Abstract: The present invention relates to a pharmaceutical composition comprising a solid dispersion of a drug. In the composition, the drug is in substantially amorphous form.
    Type: Application
    Filed: January 16, 2018
    Publication date: December 27, 2018
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Antonio ALBANO, Dipen DESAI, James DiNUNZIO, Zenaida GO, Raman Mahadevan IYER, Harpreet K. SANDHU, Navnit Hargovindas SHAH
  • Saquinavir Mesylate Oral Dosage Form
    Publication number: 20090054481
    Abstract: A solid unit oral pharmaceutical dosage form of saquinavir mesylate is provided comprising micronized saquinavir mesylate in an amount of from 250 mg to 800 mg calculated as free base, and a pharmaceutically acceptable binder, disintegrant, and water soluble carrier. A solid unit dosage form of saquinavir mesylate is provided comprising from 60% to 80% micronized saquinavir mesylate based on the mesylate salt, 4% to 8% water soluble binder, a disintegrant and a carrier, wherein each percentage is of the kernel weight.
    Type: Application
    Filed: October 31, 2008
    Publication date: February 26, 2009
    Inventors: Antonio A. Albano, Martin Howard Infeld, Wantanee Phuapradit, Navnit Hargovindas Shah, Lin Zhang
  • Pharmaceutical Solid Dosage Forms Comprising Amorphous Compounds Micro-Embedded in Ionic Water-Insoluble Polymers
    Publication number: 20080107725
    Abstract: The present invention provides novel pharmaceutical solid dosage forms for oral administration comprising a therapeutically effective amount of an unstable crystalline form or an amorphous form of a therapeutically effective compound micro-embedded into an ionic water-insoluble polymer. The therapeutically effective compounds, which have a tendency to gel, are micro-embedded into an ionic water-insoluble polymer matrix to provide a dosage form having rapid, reproducible, and complete dissolution profiles. These novel solid pharmaceutical dosage forms are useful in the treatment or control of a number of diseases. The present invention also provides a method for treating a disease comprising administering to a subject, in need thereof, a therapeutically effective amount of the novel solid pharmaceutical dosage form. The present invention further provides a method for preparing the pharmaceutical dosage forms.
    Type: Application
    Filed: October 2, 2007
    Publication date: May 8, 2008
    Inventors: Antonio Albano, Wantanee Phuapradit, Navnit Shah, Zhongshui Yu, Lin Zhang
  • Saquinavir mesylate oral dosage form
    Publication number: 20050009811
    Abstract: A solid unit oral pharmaceutical dosage form of saquinavir mesylate is provided comprising micronized saquinavir mesylate in an amount of from 250 mg to 800 mg calculated as free base, and a pharmaceutically acceptable binder, disintegrant, and water soluble carrier. A solid unit dosage form of saquinavir mesylate is provided comprising from 60% to 80% micronized saquinavir mesylate based on the mesylate salt, 4% to 8% water soluble binder, a disintegrant and a carrier, wherein each percentage is of the kernel weight.
    Type: Application
    Filed: July 8, 2004
    Publication date: January 13, 2005
    Inventors: Antonio Albano, Martin Infeld, Wantanee Phuapradit, Navnit Shah, Lin Zhang
  • Amorphous form of cell cycle inhibitor having improved solubility and bioavailability
    Patent number: 6492530
    Abstract: The present invention provides a method of preparing an amorphous, pharmaceutically active form of a compound of formula I which is substantially free of crystalline compound.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: December 10, 2002
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Antonio A. Albano, Wantanee Phuapradit, Harpreet K. Sandhu, Navnit Hargovindas Shah
  • Amorphous form of cell cycle inhibitor having improved solubility and bioavailability
    Patent number: 6486329
    Abstract: The present invention provides a method for preparing an amorphous, pharmaceutically active form of a compound of formula I which is substantially free of crystalline compound.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: November 26, 2002
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Antonio A. Albano, Wantanee Phuapradit, Harpreet K. Sandhu, Navnit Hargovindas Shah
  • AMORPHOUS FORM OF CELL CYCLE INHIBITOR HAVING IMPROVED SOLUBILITY AND BIOAVAILABILITY
    Publication number: 20020173533
    Abstract: The present invention provides a method for preparing an amorphous, pharmaceutically active form of a compound of formula I 1
    Type: Application
    Filed: April 11, 2002
    Publication date: November 21, 2002
    Inventors: Antonio A. Albano, Wantanee Phuapradit, Harpreet K. Sandhu, Navnit Hargovindas Shah
  • AMORPHOUS FORM OF CELL CYCLE INHIBITOR HAVING IMPROVED SOLUBILITY AND BIOAVAILABILITY
    Publication number: 20020173534
    Abstract: The present invention provides a method for preparing an amorphous, pharmaceutically active form of a compound of formula I 1
    Type: Application
    Filed: April 11, 2002
    Publication date: November 21, 2002
    Inventors: Antonio A. Albano, Wantanee Phuapradit, Harpreet K. Sandhu, Navnit Hargovindas Shah
  • AMORPHOUS FORM OF CELL CYCLE INHIBITOR HAVING IMPROVED SOLUBILITY AND BIOAVAILABILITY
    Publication number: 20020173532
    Abstract: The present invention provides a method of preparing an amorphous, pharmaceutically active form of a compound of formula I 1
    Type: Application
    Filed: April 11, 2002
    Publication date: November 21, 2002
    Inventors: Antonio A. Albano, Wantanee Phuapradit, Harpreet K. Sandhu, Navnit Hargovindas Shah
  • Amorphous form of cell cycle inhibitor having improved solubility and bioavailability
    Patent number: 6482847
    Abstract: The present invention provides an amorphous, pharmaceutically active form of a compound of formula I which is substantially free of crystalline compound.
    Type: Grant
    Filed: August 13, 2001
    Date of Patent: November 19, 2002
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Antonio A. Albano, Wantanee Phuapradit, Harpreet K. Sandhu, Navnit Hargovindas Shah
  • AMORPHOUS FORM OF CELL CYCLE INHIBITOR HAVING IMPROVED SOLUBILITY AND BIOAVAILABILITY
    Publication number: 20020156119
    Abstract: The present invention provides a method of preparing an amorphous, pharmaceutically active form of a compound of formula I 1
    Type: Application
    Filed: April 11, 2002
    Publication date: October 24, 2002
    Inventors: Antonio A. Albano, Wantanee Phuapradit, Harpreet K. Sandhu, Navnit Hargovindas Shah
  • Amorphous form of cell cycle inhibitor having improved solubility and bioavailability
    Patent number: 6469179
    Abstract: The present invention provides a method of preparing an amorphous, pharmaceutically active form of a compound of formula I which is substantially free of crystalline compound.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: October 22, 2002
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Antonio A. Albano, Wantanee Phuapradit, Harpreet K. Sandhu, Navnit Hargovindas Shah
  • Amorphous form of cell inhibitor having improved solubility and bioavailability
    Patent number: 6469180
    Abstract: The present invention provides a method for preparing an amorphous, pharmaceutically active form of a compound of formula I which is substantially free of crystalline compound.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: October 22, 2002
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Antonio A. Albano, Wantanee Phuapradit, Harpreet K. Sandhu, Navnit Hargovindas Shah
  • Amorphous form of cell cycle inhibitor having improved solubility and bioavailability
    Publication number: 20020061922
    Abstract: The present invention provides an amorphous, pharmaceutically active form of a compound of formula I 1
    Type: Application
    Filed: August 13, 2001
    Publication date: May 23, 2002
    Inventors: Antonio A. Albano, Wantanee Phuapradit, Harpreet K. Sandhu, Navnit Hargovindas Shah
  • Stable complexes of poorly soluble compounds in ionic polymers
    Patent number: 6350786
    Abstract: Stable water-insoluble complexes of poorly soluble compounds molecularly dispersed in water-insoluble ionic polymers are disclosed. Useful insoluble ionic polymers have a molecular weight greater than about 80,000 D and a glass transition temperature equal to or greater than about 50°. The compounds are microprecipitated in the ionic polymers in amorphous form. The complexes according to the present invention significantly increase the bioavailability of poorly soluble therapeutically active compounds.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: February 26, 2002
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Antonio A. Albano, Wantanee Phuapradit, Harpreet K. Sandhu, Navnit Hargovindas Shah