Abstract: The present disclosure provides for, among other things, methods and systems for detecting, diagnosing, predicting, monitoring, screening for, staging, and/or providing survival prognosis for advanced adenoma and/or colorectal cancer using DNA methylation markers. For example, described herein are DNA methylation markers that enable categorization and prognosis evaluation of advanced adenoma (AA) and/or colorectal cancer (CRC) patients with high accuracy from human biospecimens.

Abstract: In at least one embodiment a system including at least one switch, at least one transformer, a first active bridge and at least one controller. The at least one switch receives a first direct current (DC) input signal from a first DC charging station. The at least one transformer includes a primary side and a secondary side. The secondary side of the at least one transformer is connected to the at least one switch and transfers the first DC input signal. The first active bridge is positioned on the secondary side, the first active bridge generates a DC output signal that supplies one or more vehicle loads. The DC output signal is greater than the first DC input signal and the at least one controller programmed to activate the at least one switch in response to receiving the first DC input signal.

Abstract: A system can determine an accurate technical limit for a wellbore drilling operation using machine learning. A computing device can receive real-time data of the wellbore drilling operation; apply a machine-learning algorithm to the real-time data to determine a lost connection of the wellbore drilling operation; apply the machine-learning algorithm to determine correlations between the real-time data and historic drilling reports; and determine the technical limit for the wellbore drilling operation based on the correlations.

Abstract: A voltage converter includes a converter stage having a direct current to direct current (DC-to-DC) voltage converter, wherein the converter stage receives a first DC voltage and outputs a second DC voltage different than the first DC voltage. The voltage converter also includes a boost pre-stage having a boosting circuit and a capacitor, wherein the boost pre-stage receives a DC voltage from a battery and outputs a boosted DC voltage to the converter stage as the first voltage, wherein the boosted DC voltage is greater than the DC voltage from the battery. The boosted DC voltage of the boost pre-stage output to the converter stage provides fault resistant operation of the converter stage in the event of one or more fluctuations in an operating range of the DC voltage from the battery.

Abstract: Devices, systems, and methods for making and using highly sustainable circuit assemblies are disclosed herein. In various aspects, the highly sustainable circuit assembly includes a substrate layer; and a pattern of contact points supported by the substrate layer. The pattern of contact points can be configured to correspond to at least one terminal of an electrical component. The pattern of contact points can include a deformable conductive material. The deformable conductive material can be a non-hazardous, readily reclaimable, readily recyclable material.

Abstract: A voltage balancing circuit includes a direct-current-to-direct-current (DC-to-DC) voltage converter interconnecting a first battery having a first voltage and a second battery having a second voltage, wherein the DC-to-DC converter transfers electrical power from the first battery to the second battery when the first voltage is greater than the second voltage, and transfers electrical power from the second battery to the first battery when the first voltage is less than the second voltage, and wherein the transfer of electrical power from the first battery to the second battery or from the second battery to the first battery balances the electrical power difference between the first battery and the second battery.

Abstract: This invention describes ways of obtaining nano-particulated adjuvants formed by different synthetic variants of GM3 ganglioside. Depending on the fine structure of the fatty acid in the ceramide of the synthetic GM3, said adjuvants are able to stimulate specifically and in a specialized way the humoral or cellular immune response against accompanying antigens. Particularly, this invention provides immunogenic vaccine compositions that comprise peptides, polypeptides or proteins and the aforementioned nanoparticles, which are formed through the dispersion of hydrophobic proteins of the outer membrane complex (OMC) of Neisseria meningitidis in solutions containing fully synthetic variants of the GM3 ganglioside.

Abstract: The present application relates to providing mechanical and environmental protection to an electronics rack including a frame configured in a vertical orientation configured to receive an electronics rack, a front cover and a back cover, wherein the front cover and the back cover are configured to enclose the electronics rack when the front cover is attached to the frame and when the back cover is attached to the frame, a first fastener for mechanically coupling a top portion of the electronics rack to a top portion of the frame, a second fastener for coupling a bottom portion of the electronics rack to a bottom portion of the frame and a horizontal base for supporting the frame, the base including a mechanical interface for a material handling device, at least one castor and at least one floor lock.

Abstract: A shield enclosure includes a housing with a peripheral wall that defines a cavity, and a cover removably coupleable to the housing to at least partially seal the cavity. The cavity is sized to receive a printed circuit board therein. The housing shields the printed circuit board from electromagnetic interference and noise during noise figure testing of a radiofrequency component on the printed circuit board.

Abstract: A system and method for monitoring personal mobility vehicles in urban environments, comprising a double magnetic coil (1), disposed at an area of personal mobility vehicle traffic, and connected to an oscillator circuit (2), a phase-locked loop (3), a signal conditioning circuit (4) and a signal processor (5); where the signal processor (5) is configured to calculate the temporal variation in voltage (V(t), V?(t)) produced in the phase-locked loop (3) and due to a variation in the oscillation frequency of the double magnetic coil (1) when at least one personal mobility vehicle passes said double magnetic coil (1); and to establish the type, speed, direction of travel and length of the personal mobility vehicle that has generated the variation in the oscillation frequency of the double magnetic coil (1).

Abstract: Embodiments are disclosed for determining an answer to a query associated with a graphical representation of data. In particular, in one or more embodiments, the disclosed systems and methods comprise receiving an input including an unprocessed audio sequence and a request to perform an audio signal processing effect on the unprocessed audio sequence. The one or more embodiments further include analyzing, by a deep encoder, the unprocessed audio sequence to determine parameters for processing the unprocessed audio sequence. The one or more embodiments further include sending the unprocessed audio sequence and the parameters to one or more audio signal processing effects plugins to perform the requested audio signal processing effect using the parameters and outputting a processed audio sequence after processing of the unprocessed audio sequence using the parameters of the one or more audio signal processing effects plugins.

Abstract: In at least one embodiment, a battery charger is provided. The battery charger includes at least one transformer, a first active bridge, a second active bridge, and a pulsating buffer (PB) converter. The first active bridge is positioned on a first side of the transformer to provide a first voltage signal based on an input voltage signal from a mains supply of an electrical grid. The second active bridge is positioned on a second side of the transformer to provide a second voltage signal to store on one or more batteries based on the first voltage signal. The PB converter includes a plurality of switching devices to interface with the second active bridge to modify the second voltage signal. The plurality of switching devices provide a voltage for storage on at least one capacitor of the PB converter while modifying the second voltage signal.

Abstract: There is provided a forming system for forming a contoured composite structure having a complex curved configuration. The forming system includes a receiving station having a receiving assembly to receive a composite charge to be formed. The forming system includes a forming station having a forming assembly. The forming assembly includes a gantry assembly, an upper die assembly movably coupled to the gantry assembly, a lower die assembly coupled to a floor support beam positioned between the gantry assembly, and one or more pick-and-place devices movably coupled to the gantry assembly. The upper die assembly is separate from, and independently movable with respect to, the lower die assembly. The pick-and-place device(s) are designed to move the composite charge, and the contoured composite structure. The forming system includes a tray station having a tray assembly designed to receive the contoured composite structure from the forming station.

Abstract: A robot obtains image data representative of an environment comprising a first region and a second region. A microphone receives sound from the environment. The robot determines, using the image data and audio data derived based on the received sound, whether the sound is received from the first region, and outputs a control signal for controlling the robot based on the audio data. Sounds received from the first region are processed as voice commands on the basis that one of the first region and the second region comprises a predetermined type of inanimate object. Sounds received from the second region are processed in a different manner.

Abstract: An automated system cleans trays used in handling circuit device packages is provided in a sequential manner with pressurized air in a cleaning chamber, and a vacuum system is operated to remove the contamination (e.g. metal fibers) from the cleaning chamber. The system can convey trays in a sequential manner from one or more stacks of trays at associated tray loading stations into one or more associated cleaning chambers, and convey the cleaned trays from the one or more cleaning chambers to one or more associated tray unloading stations, where the cleaned trays are stacked. The system can handle approximately 30,000 trays per day.

Abstract: An automated method of cleaning trays used in handling circuit device packages includes the steps of: placing a plurality of trays on a tray loading station of an automated tray cleaning machine; lowering in an automated manner a first tray of the plurality of trays onto a conveyor; conveying in an automated manner the first tray from the tray loading station into a cleaning chamber; automatically applying pressurized air in the cleaning chamber to one or more surfaces of the first tray to remove debris from the first tray; conveying in an automated manner the first tray out of the cleaning chamber and to a tray unloading station; and raising in an automated manner the first tray above the conveyor.

Abstract: A DC/DC converter applies a dual active bridge (DAB) topology to convert an input DC voltage into an output DC voltage. The DC/DC converter includes a transformer, a primary stage, and a secondary stage. The primary stage includes an inductor, a first H-bridge arm having first and second power switches connected at a first node therebetween, and a second H-bridge arm having first and second capacitors connected at a second node therebetween. The inductor is connected between the first node and a terminal of an input port of the primary stage. The primary stage receives the input DC voltage at the input port of the primary stage and converts the input DC voltage into a first AC voltage. The transformer transforms the first AC voltage into a second AC voltage. The secondary stage converts the second AC voltage into the output DC voltage.

Abstract: A shield enclosure includes a housing with a peripheral wall that defines a cavity, and a cover removably coupleable to the housing to at least partially seal the cavity. The cavity is sized to receive a printed circuit board therein. The housing shields the printed circuit board from electromagnetic interference and noise during noise figure testing of a radiofrequency component on the printed circuit board.

Abstract: An on-board battery charger (OBC) includes a converter (e.g., a DC/DC converter) and a controller. An output port of the converter is connectable to a battery (e.g., a traction battery of an electric vehicle (EV)) via a voltage network (e.g., a high-voltage (HV) network of the EV). The converter converts an input power into an output power and outputs the output power onto the voltage network for charging the battery. The controller, upon detecting a transitory disconnection in the voltage network, controls the converter to stop converting the input power into the output power. In stopping the converter, the controller stops the converter prior to a corresponding reconnection in the voltage network. The controller may detect the transitory disconnection upon detecting a switching frequency of a power switch of the converter decreasing below a pre-defined threshold as the switching frequency decreases due to effects of the transitory disconnection.

Abstract: A computer-implemented method of processing audio data, the method comprising receiving input audio data (x) comprising a time-series of amplitude values; transforming the input audio data (x) into an input frequency band decomposition (X1) of the input audio data (x); transforming the input frequency band decomposition (X1) into a first latent representation (Z); processing the first latent representation (Z) by a first deep neural network to obtain a second latent representation (Z{circumflex over (?)}, Z1{circumflex over (?)}); transforming the second latent representation (Z{circumflex over (?)}, Z1{circumflex over (?)}) to obtain a discrete approximation (X3{circumflex over (?)}); element-wise multiplying the discrete approximation (X3{circumflex over (?)}) and a residual feature map (R, X5{circumflex over (?)}) to obtain a modified feature map, wherein the residual feature map (R, X5{circumflex over (?)}) is derived from the input frequency band decomposition (X1); processing a pre-shaped frequency band