Abstract: Recent remarkable progress in wave-front shaping has enabled control of light propagation inside linear media to focus and image through scattering objects. In particular, light propagation in multimode fibers comprises complex intermodal interactions and rich spatiotemporal dynamics. Control of physical phenomena in multimode fibers and its applications is in its infancy, opening opportunities to take advantage of complex mode interactions. Various embodiments of the present technology provide wave-front shaping for controlling nonlinear phenomena in multimode fibers. Using a spatial light modulator at the fiber's input and a genetic algorithm optimization, some embodiments control a highly nonlinear stimulated Raman scattering cascade and its interplay with four wave mixing via a flexible implicit control on the superposition of modes that are coupled into the fiber.

Abstract: Recent remarkable progress in wave-front shaping has enabled control of light propagation inside linear media to focus and image through scattering objects. In particular, light propagation in multimode fibers comprises complex intermodal interactions and rich spatiotemporal dynamics. Control of physical phenomena in multimode fibers and its applications is in its infancy, opening opportunities to take advantage of complex mode interactions. Various embodiments of the present technology provide wave-front shaping for controlling nonlinear phenomena in multimode fibers. Using a spatial light modulator at the fiber's input and a genetic algorithm optimization, some embodiments control a highly nonlinear stimulated Raman scattering cascade and its interplay with four wave mixing via a flexible implicit control on the superposition of modes that are coupled into the fiber.

Abstract: Recent remarkable progress in wave-front shaping has enabled control of light propagation inside linear media to focus and image through scattering objects. In particular, light propagation in multimode fibers comprises complex intermodal interactions and rich spatiotemporal dynamics. Control of physical phenomena in multimode fibers and its applications is in its infancy, opening opportunities to take advantage of complex mode interactions. Various embodiments of the present technology provide wave-front shaping for controlling nonlinear phenomena in multimode fibers. Using a spatial light modulator at the fiber's input and a genetic algorithm optimization, some embodiments control a highly nonlinear stimulated Raman scattering cascade and its interplay with four wave mixing via a flexible implicit control on the superposition of modes that are coupled into the fiber.

Abstract: An example multimode fiber endoscope may include an elongated body having a proximal end and a distal end; a multimode fiber disposed within the elongated body and extending from the proximal end to the distal end of the elongated body; a light source disposed relative to the proximal end of the elongated body; a light detector disposed relative to the proximal end of the elongated body; and multiple optical elements disposed between the light source and the multimode fiber. One or more of the optical elements are configured to direct light from the light source into the multimode fiber. One or more of the optical elements are configured to direct light from the multimode fiber to the detector. In some embodiments, the multimode fiber may be a single multimode fiber.

Abstract: Recent remarkable progress in wave-front shaping has enabled control of light propagation inside linear media to focus and image through scattering objects. In particular, light propagation in multimode fibers comprises complex intermodal interactions and rich spatiotemporal dynamics. Control of physical phenomena in multimode fibers and its applications is in its infancy, opening opportunities to take advantage of complex mode interactions. Various embodiments of the present technology provide wave-front shaping for controlling nonlinear phenomena in multimode fibers. Using a spatial light modulator at the fiber's input and a genetic algorithm optimization, some embodiments control a highly nonlinear stimulated Raman scattering cascade and its interplay with four wave mixing via a flexible implicit control on the superposition of modes that are coupled into the fiber.

Abstract: Systems and methods are disclosed to enhance three-dimensional photoacoustic imaging behind, through, or inside a scattering material. Some embodiments can increase the optical fluence in an ultrasound transducer focus and/or enhance the optical intensity using wavefront shaping before the scatterer. The photoacoustic signal induced by an object placed behind the scattering medium can serve as feedback to optimize the wavefront, enabling one order of magnitude enhancement of the photoacoustic amplitude. Using the enhanced optical intensity, the object can be scanned in two dimensions and/or a spot can be scanned by re-optimizing the wavefront before post-processing of the data to reconstruct the image. The temporal photoacoustic signal provides information to reconstruct the third-dimensional information.

Abstract: Some embodiments of the invention include a multimode fiber endoscope. The endoscope may include an elongated body having a proximal end and a distal end; a multimode fiber disposed within the elongated body and extending from the proximal end to the distal end of the elongated body, the multimode fiber; a light source disposed relative to the proximal end of the elongated body; a light detector disposed relative to the proximal end of the elongated body; and a plurality of optical elements disposed between the light source and the multimode fiber, wherein one or more of the plurality of optical elements are configured to direct light from the light source into the multimode fiber, and wherein one or more of the plurality of optical elements are configured to direct light from the multimode fiber to the detector. In some embodiments, the multimode fiber may be a single multimode fiber.