Abstract: An analyzing system is provided. The analyzing system includes a fluid container defining a sample chamber where a sample is contained in the sample chamber, and a sensor including a transparent body with a reverse face and an obverse face where the obverse face having a nanostructured surface. The nanostructured surface includes a plurality of elongate nanostructures having a respective longitudinal axis that is disposed substantially perpendicularly to the obverse face. The analyzing system includes an excitation and detection apparatus that includes an excitation source for generating a beam of polarized radiation and a corresponding radiation detector where the sensor is coupled to the fluid container such that the nanostructured surface is exposed to the sample chamber, to the sample located therein.

Abstract: An analyzing system comprises a multi-well sample carrier in which each well has a transparent bottom with a nanostructured surface inside the well. The sample carrier can be installed in a reader device so that each well of the sample carrier is aligned with a respective light guiding unit of the reader device. In use, each light guiding unit directs a beam of excitation light to the bottom of the respective well, and directs a beam of reflected light from the bottom of the respective well. The nanostructured surface acts as a plasmonic sensor to facilitate analysis of the contents of the wells. The system allows highly sensitive quantification and characterisation of biological interactions in real time across multiple wells, and with improvements in yields, quality and production times.

Abstract: An analyzing system is provided. The analyzing system includes a fluid container defining a sample chamber where a sample is contained in the sample chamber, and a sensor including a transparent body with a reverse face and an obverse face where the obverse face having a nanostructured surface. The nanostructured surface includes a plurality of elongate nanostructures having a respective longitudinal axis that is disposed substantially perpendicularly to the obverse face. The analyzing system includes an excitation and detection apparatus that includes an excitation source for generating a beam of polarized radiation and a corresponding radiation detector where the sensor is coupled to the fluid container such that the nanostructured surface is exposed to the sample chamber, to the sample located therein.