Patents by Inventor Antoon F. Mehlkopf

Antoon F. Mehlkopf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5481192
    Abstract: A magnetic resonance apparatus includes a magnet system (1) for generating a steady magnetic field in a measuring space (35), a gradient coil system (3) for generating gradient fields in the measuring space, and a power supply source (7) for the gradient coils (3) which comprises at least one gradient signal generator (9) and a number of gradient amplifiers (11), each of which is connected between an output of the gradient signal generator and at least one of the gradient coils.
    Type: Grant
    Filed: November 10, 1993
    Date of Patent: January 2, 1996
    Assignee: U.S. Philips Corporation
    Inventors: Antoon F. Mehlkopf, Cornelis L. G. Ham
  • Patent number: 5455512
    Abstract: In an MRI device operating according to a spin-echo method, switched gradient magnetic fields are applied in the form of slice selection, phase encoding and read gradients. The switching of the gradients causes eddy currents in metal parts of the apparatus. The eddy currents disturb the applied magnetic fields, thereby changing the phases of the precessing nuclear spins of a body to be examined and causing artefacts in a reconstructed image. The disturbing effects of the eddy currents is compensated for by supplementing a sequence of switched gradient magnetic fields with additional gradient fields. These additional fields have zero net effect but induce further eddy currents which compensate for the disturbing effects of the eddy currents generated by the regular switched gradient magnetic fields. The additional gradient fields are chosen such that the total time-integrated strength of a gradient in any interval between two RF-pulses is substantially equal to the desired value.
    Type: Grant
    Filed: October 26, 1993
    Date of Patent: October 3, 1995
    Assignee: U.S. Philips Corporation
    Inventors: Johannes P. Groen, Peter Van Der Meulen, Gerrit H. Van Yperen, Antoon F. Mehlkopf
  • Patent number: 5414359
    Abstract: A magnetic resonance imaging method is known for the reduction of image errors in magnetic resonance images which are caused by quantization errors in a DAC (26) for generating a phase encoding gradient waveform in an MRI measuring sequence (ms1, ms2) for generating magnetic resonance signals (S(t), S.sub.1 (t)). The known method has the drawback that inter alia the effect of differential non-linearity of the DAC (26) on the image errors is not taken into account. The invention proposes an MRI method in which such image errors are also reduced. To achieve this, prior to and/or during application of the measuring sequences (ms1, ms2), deviations of phase encoding gradient areas relative to desired areas are determined and image data in an image matrix derived from the resonance signals are corrected on the basis of said deviations.
    Type: Grant
    Filed: May 31, 1994
    Date of Patent: May 9, 1995
    Assignee: U.S. Philips Corporation
    Inventors: Antoon F. Mehlkopf, Johannes H. Den Boef
  • Patent number: 5093621
    Abstract: An MRI apparatus is proposed with an optimally adjusted gain of the detection chain, said MRI apparatus being used for generating pulse and gradient sequences which comprise an excitation pulse having a predetermined excitation angle and a phase encoding gradient. In order to obtain a data set wherefrom an MR image is reconstructed, the pulse and gradient sequence is repeated a number of times, for example 128 times, while varying the value of the time integral of the phase encoding gradient, for lower profile numbers there being chosen an excitation angle which is smaller or greater than the predetermined excitation angle in order to prevent overdriving of the detection chain. The detection chain of such an apparatus is optimally used for obtaining a data set for an MR image.
    Type: Grant
    Filed: August 29, 1990
    Date of Patent: March 3, 1992
    Assignee: U.S. Philips Corporation
    Inventors: Johannes H. Den Boef, Antoon F. Mehlkopf
  • Patent number: 5068610
    Abstract: An MRI method and device for fast determination of the transverse relaxation time constant T2 utilizes the fact that this time constant introduces asymmetry into all magnetic resonance echo signals (::exp(-t/T2) enabling determination of the time constant T2 from the asymmetry of the echo signals. During the determination of a spin density distribution the value of the time constant T2 can be determined for each pixel. After Fourier transformation of the resonance signal, integration of the imaginary terms is performed (in the coordinate direction of the measuring gradient). The quotient of the current integral and the real term of the associated pixel is an accurate measure of the time constant T2 in the relevant pixel.
    Type: Grant
    Filed: May 26, 1989
    Date of Patent: November 26, 1991
    Assignee: U.S. Philips Corporation
    Inventors: Antoon F. Mehlkopf, Willem M. Prins
  • Patent number: 5023552
    Abstract: A magnetic resonance imaging device and method are disclosed in which, during acquisition of measuring data the receiver gain is switched over in dependence of the signal strength, so that in principle every data set of the various measuring cycles has an optimum signal to noise ratio.
    Type: Grant
    Filed: October 24, 1990
    Date of Patent: June 11, 1991
    Assignee: U.S. Philips Corp.
    Inventors: Antoon F. Mehlkopf, Johannes H. Den Boef, Rolf J. M. Lioen
  • Patent number: 4879514
    Abstract: The invention relates to a magnetic resonance imaging device comprising a transmitter/receiver which, with the exception of a few components is all digital. The transmitter comprises a digital frequency synthesizer, a single sideband modulator and a selective power amplifier, the single sideband modulator being controlled by a phase locked loop oscillator. The receiver comprises a selective pre-amplifier, a frequency mixing stage which is connected either to an output of the phase locked loop oscillator or to an output of the single sideband modulator, and an analog-to-digital converter which samples the output signal of the frequency mixing stage. The demodulation frequency for the receiver is chosen so that, after demodulation, a frequency band is obtained which is situated to one side of 0 Hz.
    Type: Grant
    Filed: May 19, 1988
    Date of Patent: November 7, 1989
    Assignee: U.S. Philips Corporation
    Inventors: Antoon F. Mehlkopf, Johannes H. Den Boef