Patents by Inventor Anupam Patgiri

Anupam Patgiri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Extracellular redox enzyme system to alleviate disease
    Patent number: 11661586
    Abstract: Compositions comprising (i) lactate oxidase (LOX) and Catalase (CAT), preferably in a 1:1 molar ratio; or (ii) a fusion polypeptide comprising both LOX and CAT, e.g., LOXCAT, and methods of use thereof for reducing blood lactate levels, increasing blood pyruvate levels, and/or decreasing blood lactate/pyruvate ratio in a subject.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: May 30, 2023
    Assignee: The General Hospital Corporation
    Inventors: Vamsi K. Mootha, Xiaoyan Robert Bao, Anupam Patgiri
  • Extracellular Redox Enzyme System to Alleviate Disease
    Publication number: 20200291364
    Abstract: Compositions comprising (i) lactate oxidase (LOX) and Catalase (CAT), preferably in a 1:1 molar ratio; or (ii) a fusion polypeptide comprising both LOX and CAT, e.g., LOXCAT, and methods of use thereof for reducing blood lactate levels, increasing blood pyruvate levels, and/or decreasing blood lactate/pyruvate ratio in a subject.
    Type: Application
    Filed: December 3, 2018
    Publication date: September 17, 2020
    Inventors: Vamsi K. Mootha, Xiaoyan Robert Bao, Anupam Patgiri
  • Hydrogen bond surrogate macrocycles as modulators of Ras
    Patent number: 10221215
    Abstract: The present invention relates to peptides having one or more stable, internally-constrained HBS ?-helices, where the peptide is capable of interacting with Ras and related proteins.
    Type: Grant
    Filed: March 6, 2015
    Date of Patent: March 5, 2019
    Assignee: New York University
    Inventors: Paramjit S. Arora, Dafna Bar-Sagi, Anupam Patgiri, Kamlesh Yadav
  • Proteolytically resistant hydrogen bond surrogate helices
    Patent number: 9376469
    Abstract: The present invention relates to peptidomimetics having a stable, internally constrained protein secondary structure, where the peptidomimetics contain a hydrogen bond surrogate in the internal constraint, and at least one beta amino acid. Methods for promoting cell death using peptidomimetics that inhibit p53/hDM2 are also disclosed.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: June 28, 2016
    Assignee: New York University
    Inventors: Paramjit S. Arora, Anupam Patgiri, Stephen Joy
  • HYDROGEN BOND SURROGATE MACROCYCLES AS MODULATORS OF RAS
    Publication number: 20150239935
    Abstract: The present invention relates to peptides having one or more stable, internally-constrained HBS ?-helices, where the peptide is capable of interacting with Ras and related proteins.
    Type: Application
    Filed: March 6, 2015
    Publication date: August 27, 2015
    Applicant: New York University
    Inventors: Paramjit S. ARORA, Dafna BAR-SAGI, Anupam PATGIRI, Kamlesh YADAV
  • Hydrogen bond surrogate macrocycles as modulators of Ras
    Patent number: 8987412
    Abstract: The present invention relates to peptides having one or more stable, internally-constrained HBS ?-helices, where the peptide is capable of interacting with Ras and related proteins.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: March 24, 2015
    Assignee: New York University
    Inventors: Paramjit Arora, Dafna Bar-Sagi, Anupam Patgiri, Kamlesh Yadav
  • HYDROGEN BOND SURROGATE MACROCYCLES AS MODULATORS OF RAS
    Publication number: 20140045769
    Abstract: The present invention relates to peptides having one or more stable, internally-constrained HBS ?-helices, where the peptide is capable of interacting with Ras and related proteins.
    Type: Application
    Filed: March 2, 2012
    Publication date: February 13, 2014
    Applicant: NEW YORK UNIVERSITY
    Inventors: Paramjit Arora, Dafna Bar-Sagi, Anupam Patgiri, Kamlesh Yadav