Patents by Inventor Aparna V. Sarthy

Aparna V. Sarthy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CATIONIC LIPIDS AND USES THEREOF
    Publication number: 20100104629
    Abstract: Cationic lipids, cationic lipid based drug delivery systems, ways to make them and methods of treating diseases using them are disclosed.
    Type: Application
    Filed: September 10, 2009
    Publication date: April 29, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Prasad A. Dande, Todd M. Hansen, Robert D. Hubbard, Aparna V. Sarthy, Yu Shen, Lu Tian, Carol K. Wada, Xiaobin Zhao
  • POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF
    Publication number: 20100063135
    Abstract: Polyethylene glycol (PEG)-lipid conjugates, polyethylene glycol (PEG)-lipid conjugate based drug delivery systems, ways to make them and methods of treating diseases using them are disclosed.
    Type: Application
    Filed: September 10, 2009
    Publication date: March 11, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Prasad A. Dande, Todd M. Hansen, Robert D. Hubbard, William E. Kohlbrenner, Leiming Li, Aparna V. Sarthy, Yu Shen, Lu Tian, Carol K. Wada, Xiaobin Zhao
  • CATIONIC LIPIDS AND USES THEREOF
    Publication number: 20100055169
    Abstract: Cationic lipids, cationic lipid based drug delivery systems, ways to make them and methods of treating diseases using them are disclosed.
    Type: Application
    Filed: September 10, 2009
    Publication date: March 4, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Prasad A. Dande, Todd M. Hansen, Robert D. Hubbard, Aparna V. Sarthy, Yu Shen, Lu Tian, Carol K. Wada, Xiaobin Zhao
  • CATIONIC LIPIDS AND USES THEREOF
    Publication number: 20100055168
    Abstract: Cationic lipids, cationic lipid based drug delivery systems, ways to make them and methods of treating diseases using them are disclosed.
    Type: Application
    Filed: September 10, 2009
    Publication date: March 4, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Prasad A. Dande, Todd M. Hansen, Robert D. Hubbard, Aparna V. Sarthy, Yu Shen, Lu Tian, Carol K. Wada, Xiaobin Zhao
  • Method of killing cancer cells
    Publication number: 20040180848
    Abstract: A method of killing cancer cells comprising inhibiting the function of a gene selected from the group consisting of CDK8, STK33, PRKCM, PRKACA, ACVR1B, CDK5R1, CDC42BPB, MPP6, and CDC42BPA; pharmaceutical compositions comprising an inhibitor of the same, and a method of detecting cellular hyperplasia.
    Type: Application
    Filed: March 9, 2004
    Publication date: September 16, 2004
    Inventors: Stephen W. Fesik, Donald N. Halbert, Randy E. Metzger, Jeffrey A. McDowell, Mark E. Schurdak, Susan E. Morgan-Lappe, Aparna V. Sarthy
  • Method of killing cancer cells
    Publication number: 20040180844
    Abstract: A method of killing cancer cells comprising inhibiting the function of a gene selected from the group consisting of CDK8, STK33, PRKCM, PRKACA, ACVR1B, CDK5R1, CDC42BPB, MPP6, and CDC42BPA; pharmaceutical compositions comprising an inhibitor of the same, and a method of detecting cellular hyperplasia.
    Type: Application
    Filed: March 10, 2003
    Publication date: September 16, 2004
    Inventors: Stephen W. Fesik, Donald N. Halbert, Randy E. Metzger, Jeffrey A. McDowell, Mark E. Schurdak, Susan E. Morgan-Lappe, Aparna V. Sarthy
  • Enhanced yeast expression using regulatory control sequences from yeast sorbitol dehydrogenase gene
    Patent number: 6033898
    Abstract: An isolated DNA segment is disclosed which is derived from a Saccharomyces cerevisiae sorbitol dehydrogenase gene and which functions to increase expression of an associated foreign polypeptide when the DNA segment and the gene coding for the foreign polypeptide are operably linked in a vector in such a manner that the vector is replicated and carried by a host yeast cell. The functionally active portion of the segment is under the control (i) a transcriptional regulatory sequence of the sorbitol dehydrogenase gene of Saccharomyces cerevisiae, (ii) a translation initiation regulatory sequence of the sorbitol dehydrogenase gene of Saccharomyces cerevisiae, and (iii) a termination regulatory sequence of the sorbitol dehydrogenase gene of Saccharomyces cerevisiae. Yeast cells containing these regulatory sequences linked to a foreign DNA sequence are grown in medium containing sorbitol under conditions permitting a foreign polypeptide to be expressed.
    Type: Grant
    Filed: December 30, 1992
    Date of Patent: March 7, 2000
    Assignee: Abbott Laboratories
    Inventors: Aparna V. Sarthy, Cynthia W. Schopp
  • Enhanced yeast expression using regulatory control sequences from yeast sorbitol dehydrogenase gene
    Patent number: 6022712
    Abstract: An isolated DNA segment is disclosed which is derived from a Saccharomyces cerevisiae sorbitol dehydrogenase gene and which functions to increase expression of an associated foreign polypeptide when the DNA segment and the gene coding for the foreign polypeptide are operably linked in a vector in such a manner that the vector is replicated and carried by a host yeast cell. The functionally active portion of the segment is under the control (i) a transcriptional regulatory sequence of the sorbitol dehydrogenase gene of Saccharomyces cerevisiae, (ii) a translation initiation regulatory sequence of the sorbitol dehydrogenase gene of Saccharomyces cerevisiae, and (iii) a termination regulatory sequence of the sorbitol dehydrogenase gene of Saccharomyces cerevisiae. Yeast cells containing these regulatory sequences linked to a foreign DNA sequence are grown in medium containing sorbitol under conditions permitting a foreign polypeptide to be expressed.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: February 8, 2000
    Assignee: Abbott Laboratories
    Inventors: Aparna V. Sarthy, Cynthia W. Schopp