Patents by Inventor Apurv U. Kamath
Apurv U. Kamath has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8346338Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.Type: GrantFiled: January 27, 2011Date of Patent: January 1, 2013Assignee: DexCom, Inc.Inventors: Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
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Patent number: 8332008Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.Type: GrantFiled: March 23, 2010Date of Patent: December 11, 2012Assignee: DexCom, Inc.Inventors: Paul V. Goode, James Brauker, Apurv U. Kamath, Victoria E. Carr-Brendel
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Publication number: 20120296311Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.Type: ApplicationFiled: July 26, 2012Publication date: November 22, 2012Applicant: DexCom, Inc.Inventors: James H. Brauker, Mark A. Tapsak, Sean T. Saint, Apurv U. Kamath, Paul V. Neale, Peter C. Simpson, Michael Robert Mensinger, Dubravka Markovic
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Publication number: 20120283543Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.Type: ApplicationFiled: July 13, 2012Publication date: November 8, 2012Applicant: DexCom, IncInventors: James H. Brauker, Apurv U. Kamath, Paul V. Goode, Mark Brister
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Patent number: 8292810Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.Type: GrantFiled: January 27, 2011Date of Patent: October 23, 2012Assignee: DexCom, Inc.Inventors: Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
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Patent number: 8290562Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.Type: GrantFiled: May 3, 2010Date of Patent: October 16, 2012Assignee: DexCom, Inc.Inventors: Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, Victoria Carr-Brendel
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Patent number: 8290561Abstract: Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.Type: GrantFiled: September 23, 2009Date of Patent: October 16, 2012Assignee: DexCom, Inc.Inventors: James H. Brauker, Victoria Carr-Brendel, Paul V. Goode, Apurv U. Kamath, James P. Thrower, Ben Xavier
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Patent number: 8282549Abstract: A second numerical value 246 is shown, which is representative of a variation of the measured analyte value 242. The second numerical value is preferably determined from a variation analysis based on statistical, clinical, or physiological parameters, such as described in more detail elsewhere herein. In one embodiment, the second numerical value 246 is determined based on clinical risk (for example, weighted for the greatest possible clinical risk to a patient). In another embodiment, the second numerical representation 246 is an estimated analyte value extrapolated to compensate for a time lag, such as described in more detail elsewhere herein. In some alternative embodiments, the receiver displays a range of numerical analyte values that best represents the host's estimated analyte value (for example, +/?10%). In some embodiments, the range is weighted based on clinical risk to the patient.Type: GrantFiled: December 8, 2004Date of Patent: October 9, 2012Assignee: DexCom, Inc.Inventors: James H. Brauker, Victoria Carr-Brendel, Paul V. Goode, Apurv U. Kamath, James P. Thrower, Ben Xavier
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Patent number: 8285354Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.Type: GrantFiled: March 23, 2010Date of Patent: October 9, 2012Assignee: DexCom, Inc.Inventors: Paul V. Goode, James Brauker, Apurv U. Kamath, Victoria E. Carr-Brendel
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Patent number: 8275437Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.Type: GrantFiled: March 23, 2007Date of Patent: September 25, 2012Assignee: DexCom, Inc.Inventors: James H. Brauker, Apurv U. Kamath, Paul V. Goode, Mark Brister
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Publication number: 20120238852Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.Type: ApplicationFiled: April 30, 2012Publication date: September 20, 2012Applicant: DexCom, Inc.Inventors: James H. Brauker, Mark A. Tapsak, Sean T. Saint, Apurv U. Kamath, Paul V. Neale, Peter C. Simpson, Michael Robert Mensinger, Dubravka Markovic
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Publication number: 20120220979Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.Type: ApplicationFiled: April 30, 2012Publication date: August 30, 2012Applicant: DexCom, Inc.Inventors: James H. Brauker, Mark A. Tapsak, Sean T. Saint, Apurv U. Kamath, Paul V. Neale, Peter C. Simpson, Michael Robert Mensinger, Dubravka Markovic
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Patent number: 8251906Abstract: Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.Type: GrantFiled: April 15, 2009Date of Patent: August 28, 2012Assignee: DexCom, Inc.Inventors: James H. Brauker, Victoria Carr-Brendel, Paul V. Goode, Apurv U. Kamath, James P. Thrower, Ben Xavier
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Publication number: 20120215461Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.Type: ApplicationFiled: April 27, 2012Publication date: August 23, 2012Applicant: DexCom, Inc.Inventors: Paul V. Goode, JR., James H. Brauker, Apurv U. Kamath, James P. Thrower
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Publication number: 20120215201Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.Type: ApplicationFiled: April 30, 2012Publication date: August 23, 2012Applicant: DexCom, Inc.Inventors: James H. Brauker, Mark A. Tapsak, Sean T. Saint, Apurv U. Kamath, Paul V. Neale, Peter C. Simpson, Michael Robert Mensinger, Dubravka Markovic
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Publication number: 20120209098Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.Type: ApplicationFiled: April 27, 2012Publication date: August 16, 2012Applicant: DexCom, Inc.Inventors: Paul V. Goode, JR., James H. Brauker, Apurv U. Kamath, James P. Thrower
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Publication number: 20120190953Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.Type: ApplicationFiled: March 30, 2012Publication date: July 26, 2012Applicant: DexCom, Inc.Inventors: James H. Brauker, Mark A. Tapsak, Sean T. Saint, Apurv U. Kamath, Paul V. Neale, Peter C. Simpson, Michael Robert Mensinger, Dubravka Markovic
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Publication number: 20120186581Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.Type: ApplicationFiled: March 30, 2012Publication date: July 26, 2012Applicant: DexCom,Inc.Inventors: James H. Brauker, Mark A. Tapsak, Sean T. Saint, Apurv U. Kamath, Paul V. Neale, Peter C. Simpson, Michael Robert Mensinger, Dubravka Markovic
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Publication number: 20120191063Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.Type: ApplicationFiled: March 30, 2012Publication date: July 26, 2012Applicant: DexCom, Inc.Inventors: James H. Brauker, Mark A. Tapsak, Sean T. Saint, Apurv U. Kamath, Paul V. Neale, Peter C. Simpson, Michael Robert Mensinger, Dubravka Markovic
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Patent number: 8229535Abstract: Systems and methods for continuous measurement of an analyte in a host are provided. The system generally includes a continuous analyte sensor configured to continuously measure a concentration of analyte in a host and a sensor electronics module physically connected to the continuous analyte sensor during sensor use, wherein the sensor electronics module is further configured to directly wirelessly communicate displayable sensor information to a plurality of different types of display devices.Type: GrantFiled: February 20, 2009Date of Patent: July 24, 2012Assignee: DexCom, Inc.Inventors: Michael Robert Mensinger, John Michael Dobbles, Apurv U. Kamath, Beat Stadelmann, Deborah M. Ruppert, Nasser Salamati, Richard C. Yang