Abstract: A device for performing lateral capillary flow may comprise a housing having a proximal end and a distal end, said housing comprising an interior defined between a lower base portion and an upper portion coupled to the lower base portion, wherein the interior includes a region sized and shaped to receive a capillary flow matrix. A reservoir may be located in the upper portion of the housing proximate the proximal end of the housing, the reservoir having an inlet accessible from an exterior of the housing and an outlet in flow communication with an interior of the housing at a location above the region. The device may further comprise a support system disposed in the interior of the housing, the support system comprising a surface positioned in the region sized and shaped to receive a capillary flow matrix and in alignment with the outlet of the reservoir, the surface being configured to receive and support a capillary flow matrix received in the region.

Abstract: Disclosed is a lateral flow capillary device and uses thereof comprising a unipath capillary flow matrix and a plurality of reservoirs each in fluid communication with the capillary flow matrix. The device includes one or more pressure delivery systems configured to urge capillary flow matrix toward a portion of the housing in which it resides, such that a substantially uniform pressure is applied over a portion of the capillary flow matrix.

Abstract: Disclosed is a lateral flow capillary device and uses thereof comprising a unipath capillary flow matrix and a plurality of reservoirs each in fluid communication with the capillary flow matrix. The device includes one or more pressure delivery systems configured to urge capillary flow matrix toward a portion of the housing in which it resides, such that a substantially uniform pressure is applied over a portion of the capillary flow matrix.

Abstract: An apparatus for producing an image of blotting membranes includes an enclosure, light source, optical system, photodetector, and beamsplitter. The enclosure supports a blotting substrate comprising a first probe characterized by an excitation wavelength and an emission wavelength and a second probe characterized by an excitation wavelength and an emission wavelength. The light source directs diverging light to illuminate an entirety of the active area. The optical system forms an image of the entire active area and comprises an optical filter, the optical filter having an optical characteristic highly transmissive of light at the emission wavelengths and highly reflective of light at the excitation wavelengths. The beamsplitter may comprise an optical characteristic that is highly transmissive of light at the first and second emission wavelengths and that is highly reflective of light at the first and second excitation wavelengths.

Abstract: Disclosed is a lateral flow capillary device and uses thereof comprising a unipath capillary flow matrix and a plurality of reservoirs each in fluid communication with the capillary flow matrix. The device includes one or more pressure delivery systems configured to urge capillary flow matrix toward a portion of the housing in which it resides, such that a substantially uniform pressure is applied over a portion of the capillary flow matrix.

Abstract: Disclosed is a lateral flow capillary device and uses thereof comprising a unipath capillary flow matrix and a plurality of reservoirs each in fluid communication with the capillary flow matrix. The device includes one or more pressure delivery systems configured to urge capillary flow matrix toward a portion of the housing in which it resides, such that a substantially uniform pressure is applied over a portion of the capillary flow matrix.

Abstract: Disclosed is a method for diagnosing multiple sclerosis and more particularly to a method for diagnosing multiple sclerosis by measuring levels of antibodies to glycans in a biological sample.

Abstract: Disclosed is a method for diagnosing multiple sclerosis and more particularly to a method for diagnosing multiple sclerosis by measuring levels of antibodies to glycans in a biological sample.

Abstract: Disclosed is a method for diagnosing multiple sclerosis and more particularly to a method for diagnosing multiple sclerosis by measuring levels of antibodies to glycans in a biological sample.

Abstract: Disclosed is a method for diagnosing multiple sclerosis and more particularly to a method for diagnosing multiple sclerosis by measuring levels of antibodies to glycans in a biological sample.