Abstract: An assembly is provided which can crimp or compress an intraluminal device or measure the radial strength of an intraluminal device. The crimping assembly includes at least two moving-element subassemblies, each with a pair of moving elements. The moving elements having a first side and a second side joining at a tip. The moving-element subassembly is able to move in such a way that the moving elements move relative to each other from a first position with the tips offset from each other by a first distance, to a second position with the tips offset from each other by a second distance different than the first distance. The assembly also includes a movement assembly that interfaces with each of the moving-element subassemblies. The movement assembly moves the pairs of moving elements between the first position and the second position.

Abstract: A balloon catheter having an elongated shaft and a balloon mounted on the distal portion of the shaft, the balloon having a working section and proximal and distal end portions that extend inwardly with respect to the working section and which are secured to the catheter shaft within the working section. The end portions are therefore inverted recesses on each end of the balloon. A stent may be disposed about the balloon to form a stent deploying system. The proximal and distal end portions may contain a tapered portion, which tapers from the balloon working section to the catheter shaft with decreasing transverse dimension. The end portions may be connected to the working section with connecting fibers. This design allows for improved expansion and stent placement in the vasculature.

Abstract: An assembly is provided which can crimp or compress an intraluminal device or measure the radial strength of an intraluminal device. The device includes a first disk and a second disk for imparting movement to a number of spaced apart moving elements attached to linear sliders on the first disk. In one configuration, rotational movement is imparted to the second disk which causes the tips of the moving elements to move is a linear direction toward the center of the opening formed by the elements thereby closing in on the device. In another configuration, rotational movement is imparted to the first disk and the tips move along an arcuate path from the perimeter of the opening toward the center of the opening.

Abstract: An embolic protection device for use in a blood vessel when an interventional procedure is being performed in a stenosed or occluded region to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filtering assembly having a self-expanding strut assembly and a filter element attached thereto. In one embodiment, the filtering assembly is attached to the distal end of a guidewire and is deployed within the patient's vasculature as the guidewire is manipulated into the area of treatment. A restraining sheath placed over the filtering assembly in a coaxial arrangement maintains the filtering assembly in its collapsed position until it is ready to be deployed by the physician. Thereafter, the sheath can be retracted to expose the filtering assembly which will then self-expand within the patient's vasculature.

Abstract: A catheter apparatus includes a lesion dilating member disposable at a lesion position in a vessel (e.g. a patient's artery) which is dilatable to open the vessel at the lesion position. An emboli-capturing assembly having a perfusion member and filter is displaced downstream from the lesion dilating member to capture embolic debris released in the fluid flow. The perfusion member may illustratively have peaks and channels formed between adjacent peaks which cooperate with the filter to create trapping pockets that capture embolic debris. The filter may be made from any flexible and porous material with dimensions to pass the fluid and block the emboli. The perfusion member is thereafter deflated to provide for emboli retention in the perfusion member.

Abstract: An assembly is provided which can crimp or compress an intraluminal device or measure the radial strength of an intraluminal device. The crimping assembly includes at least two moving-element subassemblies, each with a pair of moving elements. The moving elements having a first side and a second side joining at a tip. The moving-element subassembly is able to move in such a way that the moving elements move relative to each other from a first position with the tips offset from each other by a first distance, to a second position with the tips offset from each other by a second distance different than the first distance. The assembly also includes a movement assembly that interfaces with each of the moving-element subassemblies. The movement assembly moves the pairs of moving elements between the first position and the second position.

Abstract: An embolic protection device includes a filtering assembly having a self-expanding strut assembly and a filter element. The filtering assembly can be attached to a guidewire and deployed within the patient's vasculature into an area of treatment. A restraining sheath maintains the filtering assembly in its collapsed position until it is ready to be deployed by the physician. Interventional devices can be delivered over the guidewire and any embolic debris created and released into the blood stream will enter the filtering assembly. The filtering assembly can be rotatably mounted on the guide wire and may include a dampening element which helps to prevent some shock force that may be transmitted along the guide to the deployed filtering assembly.

Abstract: An assembly is provided which can crimp or compress an intraluminal device or measure the radial strength of an intraluminal device. The device includes a stationary disk and a drive disk for imparting movement to a number of wedges attached to linear sliders on the stationary disk. As rotational movement is imparted by the drive disk to the wedges, the wedges move in a linear direction to form a crimping motion for use in crimping an intravascular intraluminal device onto a catheter or a mandrel. Alternatively, the same motion of the wedges is used to measure the radial strength of an intraluminal device.

Abstract: A catheter including an injection port at or near the distal end thereof and a mechanism for causing the injection port to move between a first position and a second position. In the first position the injection port is substantially aligned with a central axis of the catheter. Upon activation of the mechanism, the injection port moves between the first position and the second position perpendicular to the central axis of the catheter. The mechanism also causes the injection port to move away from the central axis of the catheter and into a wall of the vasculature.

Abstract: An assembly is provided which can crimp or compress an intraluminal device or measure the radial strength of an intraluminal device. The device includes a stationary disk and a drive disk for imparting movement to a number of wedges attached to linear sliders on the stationary disk. As rotational movement is imparted by the drive disk to the wedges, the wedges move in a linear direction to form a crimping motion for use in crimping an intravascular intraluminal device onto a catheter or a mandrel. Alternatively, the same motion of the wedges is used to measure the radial strength of an intraluminal device.

Abstract: An assembly is provided which can crimp or compress an intraluminal device or measure the radial strength of an intraluminal device. The device includes a first disk and a second disk for imparting movement to a number of spaced apart moving elements attached to linear sliders on the first disk. In one configuration, rotational movement is imparted to the second disk which causes the tips of the moving elements to move is a linear direction toward the center of the opening formed by the elements thereby closing in on the device. In another configuration, rotational movement is imparted to the first disk and the tips move along an arcuate path from the perimeter of the opening toward the center of the opening.

Abstract: The invention is directed to an inflatable member for delivery of therapeutic agents to a desired site within a patient's body, in particular, balloons for use with balloon catheters and stent delivery systems; balloon catheters and stent delivery systems including the same; and methods for making and using the same. The inflatable member of the present invention includes an outer and an inner layer and an outer chamber therebetween for housing the therapeutic agent. The outer layer includes apertures for releasing the therapeutic agent to the desired site. Optionally, the inner layer may also include perforations.

Abstract: A catheter apparatus includes a lesion dilating member disposable at a lesion position in a vessel (e.g. a patient's artery) which is dilatable to open the vessel at the lesion position. An emboli-capturing assembly having a perfusion member and filter is displaced downstream from the lesion dilating member to capture embolic debris released in the fluid flow. The perfusion member may illustratively have peaks and channels formed between adjacent peaks which cooperate with the filter to create trapping pockets that capture embolic debris. The filter may be made from any flexible and porous material with dimensions to pass the fluid and block the emboli. The perfusion member is thereafter deflated to provide for emboli retention in the perfusion member.

Abstract: The emboli protection system provides one or more inflatable blocking balloons for isolation of a section of a blood vessel to prevent migration of emboli from the section during an interventional procedure, and fluid infusion and evacuation ports for flushing emboli from the isolated section. One embodiment provides for a distal blocking balloon catheter, over which an interventional device can be introduced, and a proximal blocking balloon catheter to be introduced over the interventional device for isolating a portion of a blood vessel to be treated. The blocking balloons can be perforated to provide the infusion ports, and thrombolytic inflation fluid may be used to break down and dissolve thrombus and plaque in the isolated portion of the blood vessel.

Abstract: A balloon catheter having an elongated shaft and a balloon mounted on the distal portion of the shaft, the balloon having a working section and proximal and distal end portions that extend inwardly with respect to the working section and which are secured to the catheter shaft within the working section. The end portions are therefore inverted recesses on each end of the balloon. A stent may be disposed about the balloon to form a stent deploying system. The proximal and distal end portions may contain a tapered portion, which tapers from the balloon working section to the catheter shaft with decreasing transverse dimension. The end portions may be connected to the working section with connecting fibers. This design allows for improved expansion and stent placement in the vasculature.

Abstract: A balloon catheter having an elongated shaft and a balloon mounted on the distal portion of the shaft, the balloon having a working section and proximal and distal end portions that extend inwardly with respect to the working section and which are secured to the catheter shaft within the working section. The end portions are therefore inverted recesses on each end of the balloon. A stent may be disposed about the balloon to form a stent deploying system. The proximal and distal end portions may contain a tapered portion, which tapers from the balloon working section to the catheter shaft with decreasing transverse dimension. The end portions may be connected to the working section with connecting fibers. This design allows for improved expansion and stent placement in the vasculature.

Abstract: I An endoscope having a deflection control and a shaft connected to the deflection control. The shaft has a deflectable section operably connected to the deflection control by drive cables. The deflectable section comprises rigid rings and flexible connection members connecting the rings to each other. The connection members are comprised of a superelastic shape memory alloy. The connection members retain the deflectable section in a predetermined shape. The connection members can be resiliently bent to bend the deflectable section without permanent deformation of the connection member over a working life of the endoscope.

Abstract: An articulation mechanism for an endoscope wherein the endoscope has a generally elongated shaft and cables extending between a control head located at the proximal end thereof and an objective assembly located at the distal end thereof wherein the objective assembly is capable of being deflected over an arcuate co-planar path by the articulation mechanism is shown. The articulation mechanism comprises a proximal ring having a first outer edge and a second outer edge and the proximal ring is operative coupled to the distal end of the endoscope at one of the first outer ring and second outer ring and having a coupling member defined on the other of the first outer ring and second outer ring. A central ring having a first outer edge and a second outer edge, each of which defines an actuation member, is operatively connected by one of the actuation members to the coupling member.