Patents by Inventor Arlene Correa

Arlene Correa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the enantioselective preparation of phenylisoserine derivatives
    Patent number: 5292921
    Abstract: Process for the enantioselective preparation of phenylisoserine derivatives of general formula (I) ##STR1## from phenylglycine S(+) wherein R is a phenyl radical or a tert butoxy radical and R is an alcohol protective group.
    Type: Grant
    Filed: November 13, 1992
    Date of Patent: March 8, 1994
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Arlene Correa, Jean-Noel Denis, Andrew-Elliot Greene, David S. Grierson
  • Process for the stereoselective preparation of phenylisoserine derivatives used in making taxols
    Patent number: 5290957
    Abstract: A stereoselective process for preparing phenylisoserine derivatives is disclosed. Benzylamine is reacted with an agent for introducing a phenyl or a t-butoxycarbonyl group. The product undergoes double anionization and then is reacted with acrolein to provide a mixture of alcohol syn and anti diasteroisomers. The syn isomer is isolated by chromatography. Whereupon, the hydroxyl is protected and the product is oxidized to provide the phenylisoserine derivative.
    Type: Grant
    Filed: November 20, 1992
    Date of Patent: March 1, 1994
    Assignee: Rhone Poulenc Rorer S.A.
    Inventors: Arlene Correa, Jean-Noel Denis, Andrew-Elliot Greene