Patents by Inventor Armin Sepp

Armin Sepp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selection
    Publication number: 20090176209
    Abstract: The present invention to a nucleotide sequence encoding one or more Arc DNA binding domains, one or more Arc DNA binding sites and at least one polypeptide domain.
    Type: Application
    Filed: January 17, 2007
    Publication date: July 9, 2009
    Applicant: Domantis Limited
    Inventors: Armin Sepp, Andrew Griffiths
  • Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
    Publication number: 20090081233
    Abstract: Disclosed are ligands that have binding specificity for vascular endothelial growth factor (VEGF), for epidermal growth factor receptor (EGFR), or for VEGF and EGFR. Also disclosed are methods of using these ligands. In particular, the use of these ligands for cancer therapy is described.
    Type: Application
    Filed: July 9, 2008
    Publication date: March 26, 2009
    Applicant: Domantis Limited
    Inventors: Olga Ignatovich, Steve Holmes, Roland Beckmann, Rudolf M.T. de Wildt, Armin Sepp
  • Optical sorting method
    Publication number: 20090053700
    Abstract: The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; (b) expressing the genetic elements to produce their respective gene products within the microcapsules; (c) sorting the genetic elements which produce the gene product having the desired activity using a change in the optical properties of the genetic elements. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention.
    Type: Application
    Filed: June 18, 2007
    Publication date: February 26, 2009
    Inventors: Andrew Griffiths, Dan Tawfik, Armin Sepp
  • Tus DNA binding domains
    Publication number: 20080038735
    Abstract: The present invention relates to a nucleic sequence encoding one or more Tus DNA binding domains, one or more DNA binding sites and at least one polypeptide domain.
    Type: Application
    Filed: March 26, 2007
    Publication date: February 14, 2008
    Applicant: Domantis Limited
    Inventors: Armin Sepp, Albert Stoop
  • Optical sorting method
    Publication number: 20050164239
    Abstract: The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; (b) expressing the genetic elements to produce their respective gene products within the microcapsules; (c) sorting the genetic elements which produce the gene product having the desired activity using a change in the optical properties of the genetic elements. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention.
    Type: Application
    Filed: October 1, 2004
    Publication date: July 28, 2005
    Inventors: Andrew Griffiths, Dan Tawfik, Armin Sepp
  • Optical sorting method
    Publication number: 20050037392
    Abstract: The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; (b) expressing the genetic elements to produce their respective gene products within the microcapsules; (c) sorting the genetic elements which produce the gene product having the desired activity using a change in the optical properties of the genetic elements. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention.
    Type: Application
    Filed: June 11, 2004
    Publication date: February 17, 2005
    Inventors: Andrew Griffiths, Dan Tawfik, Armin Sepp
  • Optical sorting method
    Patent number: 6808882
    Abstract: The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; (b) expressing the genetic elements to produce their respective gene products within the microcapsules; (c) sorting the genetic elements which produce the gene product having the desired activity using a change in the optical properties of the genetic elements. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: October 26, 2004
    Assignee: Medical Research Council
    Inventors: Andrew Griffiths, Dan Tawfik, Armin Sepp
  • Composition binding polypeptides
    Publication number: 20040197892
    Abstract: Disclosed herein are polypeptides with novel DNA binding specificities, constructed from combinations of zinc fingers, and methods for their preparation and use.
    Type: Application
    Filed: April 26, 2004
    Publication date: October 7, 2004
    Inventors: Michael Moore, Armin Sepp, Mark Isalan, Yen Choo