Patents by Inventor Armin Tahmasbi Rad

Armin Tahmasbi Rad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIGEL TUMOR-ON-A-CHIP SYSTEM
    Publication number: 20240067911
    Abstract: Described herein are apparati and methods for growing cells in a manner that mimics the native three-dimensional environment. Cell cultures grown in the apparatus can be screened for inhibition by specific chemotherapeutics or other drugs.
    Type: Application
    Filed: August 3, 2023
    Publication date: February 29, 2024
    Inventors: Mu-Ping Nieh, Armin Tahmasbi Rad, Reza Amin, Leila Daneshmandi
  • Discoidal nano universal platform for efficient delivery of PNAs
    Patent number: 11833254
    Abstract: A self-assembled discoidal PNA delivery vehicle includes a zwitterionic short chain diacyl lipid, a zwitterionic long chain diacyl lipid, a charged long chain diacyl lipid, a PEGylated lipid of the formula distearoyl phosphoethanolamine (DSPE)-PEGn-TG, and an encapsulated PNA molecule with a defined molar ratio of the zwitterionic long chain diacyl lipid and the charged long chain diacyl lipid to the short chain diacyl lipid, the molar ratio of the charged long chain diacyl lipid to the zwitterionic long chain diacyl lipid, molar % of the PEGylated lipid to all lipids, and ratio of PNA to lipid. Also described are method of self-assembling the discoidal PNA delivery vehicle and methods of enhancing cellular uptake of PNA using the discoidal PNA delivery vehicle.
    Type: Grant
    Filed: May 27, 2021
    Date of Patent: December 5, 2023
    Assignee: UNIVERSITY OF CONNECTICUT
    Inventors: Raman Bahal, Mu-Ping Nieh, Armin Tahmasbi Rad, Shipra Malik
  • Multigel tumor-on-a-chip system
    Patent number: 11760966
    Abstract: Described herein are apparata and methods for growing cells in a manner that mimics the native three-dimensional environment. Cell cultures grown in the apparatus can be screened for inhibition by specific chemotherapeutics or other drugs.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: September 19, 2023
    Assignee: University of Connecticut
    Inventors: Mu-Ping Nieh, Armin Tahmasbi Rad, Reza Amin, Leila Daneshmandi
  • Discoidal Nano Universal Platform for Efficient Delivery of PNAs
    Publication number: 20210369632
    Abstract: A self-assembled discoidal PNA delivery vehicle includes a zwitterionic short chain diacyl lipid, a zwitterionic long chain diacyl lipid, a charged long chain diacyl lipid, a PEGylated lipid of the formula distearoyl phosphoethanolamine (DSPE)-PEGn-TG, and an encapsulated PNA molecule with a defined molar ratio of the zwitterionic long chain diacyl lipid and the charged long chain diacyl lipid to the short chain diacyl lipid, the molar ratio of the charged long chain diacyl lipid to the zwitterionic long chain diacyl lipid, molar % of the PEGylated lipid to all lipids, and ratio of PNA to lipid. Also described are method of self-assembling the discoidal PNA delivery vehicle and methods of enhancing cellular uptake of PNA using the discoidal PNA delivery vehicle.
    Type: Application
    Filed: May 27, 2021
    Publication date: December 2, 2021
    Inventors: Raman Bahal, Mu-Ping Nieh, Armin Tahmasbi Rad, Shipra Malik
  • MULTIGEL TUMOR-ON-A-CHIP SYSTEM
    Publication number: 20200392440
    Abstract: Described herein are apparata and methods for growing cells in a manner that mimics the native three-dimensional environment. Cell cultures grown in the apparatus can be screened for inhibition by specific chemotherapeutics or other drugs.
    Type: Application
    Filed: June 12, 2020
    Publication date: December 17, 2020
    Inventors: Mu-Ping Nieh, Armin Tahmasbi Rad, Reza Amin, Leila Daneshmandi