Patents by Inventor Armin Walser

Armin Walser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzoimidazole-carboxylic acid amide derivatives as APJ receptor modulators
    Patent number: 9156796
    Abstract: The present invention relates to benzoimidazole-carboxylic acid amide compounds of the formula I, in which R?, R?, R??, R1, R2, R3, R4, R5, R6 and Z are defined as indicated below. The compounds of the formula I are APJ receptor modulators, and are useful for the treatment of diseases associated with increased blood pressure for example. The invention furthermore relates to the use of compounds of the formula I, in particular as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: October 13, 2015
    Assignee: SANOFI
    Inventors: Stephanie Hachtel, Paulus Wohlfart, John Weston, Marco Mueller, Elisabeth Defossa, Katharina Mertsch, Jian-Hui Weng, Robert Alan Binnie, Farid Abdul-Latif, William Jerome Bock, Armin Walser
  • BENZOIMIDAZOLE-CARBOXYLIC ACID AMIDE DERIVATIVES AS APJ RECEPTOR MODULATORS
    Publication number: 20140094450
    Abstract: The present invention relates to benzoimidazole-carboxylic acid amide compounds of the formula I, in which R?, R?, R??, R1, R2, R3, R4, R5, R6 and Z are defined as indicated below. The compounds of the formula I are APJ receptor modulators, and are useful for the treatment of diseases associated with increased blood pressure for example. The invention furthermore relates to the use of compounds of the formula I, in particular as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.
    Type: Application
    Filed: September 19, 2013
    Publication date: April 3, 2014
    Applicant: SANOFI
    Inventors: Stephanie HACHTEL, Paulus WOHLFART, John WESTON, Marco MUELLER, Elisabeth DEFOSSA, Katharina MERTSCH, Jian-Hui WENG, Robert Alan BINNIE, Farid ABDUL-LATIF, William Jerome BOCK, Armin WALSER
  • Acylated indanyl amines and their use as pharmaceuticals
    Patent number: 8163751
    Abstract: The present invention relates to acylated indanyl amines according to the general formula (I) wherein R1-R4 have the meanings given in the description, A is CH2, CHOH or CH—(C1-C3-alkyl), B is CH2 or CH—(C1-C3-alkyl), and R5 is an aryl or heteroaryl group, possibly substituted by the substituents listed in the description.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: April 24, 2012
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Hartmut Strobel, Paulus Wohlfart, Alena Safarova, Armin Walser, Teri Suzuki, Karl Schönafinger, Ramalinga M. Dharanipragada
  • ACYLATED INDANYL AMINES AND THEIR USE AS PHARMACEUTICALS
    Publication number: 20100183712
    Abstract: The present invention relates to acylated indanyl amines according to the general formula (I) wherein R1-R4 have the meanings given in the description, A is CH2, CHOH or CH—(C1-C3-alkyl), B is CH2 or CH—(C1-C3-alkyl), and R5 is an aryl or heteroaryl group, possibly substituted by the substituents listed in the description.
    Type: Application
    Filed: March 29, 2010
    Publication date: July 22, 2010
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Hartmut STROBEL, Paulus WOHLFART, Alena SAFAROVA, Armin WALSER, Teri SUZUKI, Karl SCHÖNAFINGER, Ramalinga M. DHARANIPRAGADA
  • Acylated indanyl amines and their use as pharmaceuticals
    Patent number: 7713963
    Abstract: The present invention relates to acylated indanyl amines according to the general formula (I) wherein R1—R4 have the meanings given in the description, A is CH2, CHOH or CH—(C1-C3-alkyl), B is CH2 or CH—(C1-C3-alkyl), and R5 is an aryl or heteroaryl group, possibly substituted by the substituents listed in the description.
    Type: Grant
    Filed: October 11, 2006
    Date of Patent: May 11, 2010
    Assignee: sanofi-aventis Deutschland GmbH
    Inventors: Hartmut Strobel, Paulus Wohlfart, Alena Safarova, Armin Walser, Teri Suzuki, Karl Schoenafinger, Ramalinga M. Dharanipragada
  • Substituted sulfonamides and ureas useful for inhibiting kinase activity
    Patent number: 7393849
    Abstract: Sulfonamide and urea compounds having an inhibitory effect on Src kinase including enantiomers, stereoisomers and tautomers thereof, as well as pharmaceutically acceptable salts or solvates of said compound, said compound having the general structure shown in Formula II are disclosed and claimed:
    Type: Grant
    Filed: April 23, 2007
    Date of Patent: July 1, 2008
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Pavel Safar, Armin Walser, Stephen James Shimshock
  • Substituted sulfonamides and ureas useful for inhibiting kinase activity
    Patent number: 7323457
    Abstract: Sulfonamide and urea compounds having an inhibitory effect on Src kinase including enantiomers, stereoisomers and tautomers thereof, as well as pharmaceutically acceptable salts or solvates of said compound, said compound having the general structure shown in Formula II are disclosed and claimed:
    Type: Grant
    Filed: April 23, 2007
    Date of Patent: January 29, 2008
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Pavel Safar, Armin Walser, Stephen James Shimshock
  • SUBSTITUTED SULFONAMIDES AND UREAS USEFUL FOR INHIBITING KINASE ACTIVITY
    Publication number: 20070208008
    Abstract: Sulfonamide and urea compounds having an inhibitory effect on Src kinase including enantiomers, stereoisomers and tautomers thereof, as well as pharmaceutically acceptable salts or solvates of said compound, said compound having the general structure shown in Formula II are disclosed and claimed:
    Type: Application
    Filed: April 23, 2007
    Publication date: September 6, 2007
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: Pavel SAFAR, Armin WALSER, Stephen SHIMSHOCK
  • SUBSTITUTED SULFONAMIDES AND UREAS USEFUL FOR INHIBITING KINASE ACTIVITY
    Publication number: 20070191347
    Abstract: Sulfonamide and urea compounds having an inhibitory effect on Src kinase including enantiomers, stereoisomers and tautomers thereof, as well as pharmaceutically acceptable salts or solvates of said compound, said compound having the general structure shown in Formula II are disclosed and claimed:
    Type: Application
    Filed: April 23, 2007
    Publication date: August 16, 2007
    Inventors: Pavel SAFAR, Armin WALSER, Stephen SHIMSHOCK
  • Substituted sulfonamides and ureas useful for inhibiting kinase activity
    Patent number: 7223763
    Abstract: Sulfonamide and urea compounds having an inhibitory effect on Src kinase including enantiomers, stereoisomers and tautomers thereof, as well as pharmaceutically acceptable salts or solvates of said compound, said compound having the general structure shown in Formula II are disclosed and claimed:
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: May 29, 2007
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Pavel Safar, Armin Walser, Stephen James Shimshock
  • ACYLATED INDANYL AMINES AND THEIR USE AS PHARMACEUTICALS
    Publication number: 20070082897
    Abstract: The present invention relates to acylated indanyl amines according to the general formula (I) wherein R1—R4 have the meanings given in the description, A is CH2, CHOH or CH—(C1-C3-alkyl), B is CH2 or CH—(C1-C3-alkyl), and R5 is an aryl or heteroaryl group, possibly substituted by the substituents listed in the description.
    Type: Application
    Filed: October 11, 2006
    Publication date: April 12, 2007
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Hartmut STROBEL, Paulus WOHLFART, Alena SAFAROVA, Armin WALSER, Teri SUZUKI, Karl SCHONAFINGER, Ramalinga DHARANIPRAGADA
  • 4-fluoro-N-indan-2-yl benzamide and its use as a pharmaceutical
    Patent number: 7202278
    Abstract: A method of stimulating the expression of endothelial NO-synthase in a mammal, which method comprises administering a physiologically active amount of 4-fluoro-N-indan- 2-yl benzamide according to the formula (I) to the said mammal.
    Type: Grant
    Filed: August 18, 2004
    Date of Patent: April 10, 2007
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Paulus Wohlfart, Teri Suzuki, Ramalinga M. Dharanipragada, Alena Safarova, Armin Walser, Hartmut Strobel
  • Acylated indanyl amines and their use as pharmaceuticals
    Patent number: 7179839
    Abstract: The present invention relates to acylated indanyl amines according to the general formula (I) wherein R1–R4 have the meanings given in the description, A is CH2, CHOH or CH—(C1–C3-alkyl), B is CH2 or CH—(C1–C3-alkyl), and R5 is an aryl or heteroaryl group, possibly substituted by the substituents listed in the description.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: February 20, 2007
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Hartmut Strobel, Paulus Wohlfart, Alena Safarova, Armin Walser, Teri Suzuki, Karl Schönafinger
  • Substituted diaryl heterocycles, process for their preparation and their use as medicaments
    Patent number: 7141561
    Abstract: This invention discloses and claims diary heterocycles of formula (I) and their pharmaceutically acceptable salts, pharmaceutical compositions thereof, and methods of using said compounds of formula (I) for the treatment or prevention of excessive weight or obesity, and for treatment of Type II diabetes, arteriosclerosis, high blood pressure, depression, anxiety, anxiety neuroses, and schizophrenia. Methods for treatment of excessive weight or obesity and for treatment of Type II diabetes with a mixture of a compound of formula I and antiobesity agents or appetite-regulating active ingredients, or with a mixture of a compound of formula I and antidiabetics or hypoglycemic active ingredients are also disclosed and claimed.
    Type: Grant
    Filed: July 24, 2003
    Date of Patent: November 28, 2006
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Lothar Schwink, Siegfried Stengelin, Matthias Gossel, Thomas Boehme, Gerhard Hessler, Gerard Rosse, Armin Walser
  • 4-Fluoro-N-indan-2-yl benzamide and its use as a pharmaceutical
    Publication number: 20050054729
    Abstract: The present invention relates to the method of stimulating the expression of endothelial NO-synthase in a mammal, which method comprises administering a physiologically active amount of 4-fluoro-N-indan-2-yl benzamide according to the formula (I) to the said mammal.
    Type: Application
    Filed: August 18, 2004
    Publication date: March 10, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Paulus Wohlfart, Teri Suzuki, Ramalinga Dharanipragada, Alena Safarova, Armin Walser, Hartmut Strobel
  • 4-Fluoro-N-indan-2-yl benzamide and its use as a pharmaceutical
    Patent number: 6812253
    Abstract: The present invention relates to the method of stimulating the expression of endothelial NO-synthase in a mammal, which method comprises administering a physiologically active amount of 4-fluoro-N-indan-2-yl benzamide according to the formula (I) to the said mammal.
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: November 2, 2004
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Paulus Wohlfart, Teri Suzuki, Ramalinga M. Dharanipragada, Alena Safarova, Armin Walser, Hartmut Strobel
  • Substituted sulfonamides and ureas useful for inhibiting kinase activity
    Publication number: 20040204582
    Abstract: Sulfonamide and urea compounds having an inhibitory effect on Src kinase including enantiomers, stereoisomers and tautomers thereof, as well as pharmaceutically acceptable salts or solvates of said compound, said compound having the general structure shown in Formula II are disclosed and claimed: 1
    Type: Application
    Filed: April 30, 2004
    Publication date: October 14, 2004
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Pavel Safar, Armin Walser, Stephen James Shimshock
  • Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals
    Publication number: 20040198733
    Abstract: The present invention relates to aminoalkyl-substituted aromatic bicyclic compounds of formula I, 1
    Type: Application
    Filed: April 9, 2004
    Publication date: October 7, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Lothar Schwink, Siegfried Stengelin, Matthias Gossel, Armin Walser, Gerard Rosse
  • Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals
    Publication number: 20040198732
    Abstract: The present invention relates to aminoalkyl-substituted aromatic bicyclic compounds of formula I, 1
    Type: Application
    Filed: April 9, 2004
    Publication date: October 7, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Lothar Schwink, Siegfried Stengelin, Matthias Gossel, Armin Walser, Gerard Rosse
  • Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals
    Publication number: 20040198731
    Abstract: The present invention relates to aminoalkyl-substituted aromatic bicyclic compounds of formula I, 1
    Type: Application
    Filed: April 9, 2004
    Publication date: October 7, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Lothar Schwink, Siegfried Stengelin, Matthias Gossel, Armin Walser, Gerard Rosse