Patents by Inventor Arnaud Debin

Arnaud Debin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conjugated TLR7 and/or TLR8 and TLR2 agonists
    Patent number: 9567336
    Abstract: A conjugated compound of formula Q-Z—R4 wherein Q is a TLR7 and/or TLR8 agonist and Z—R4 is a TLR2 agonist, and the uses thereof in the treatment of infection, cancer or immune disorders or for use in vaccines.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: February 14, 2017
    Assignee: INVIVOGEN
    Inventors: Fabienne Vernejoul, Arnaud Debin, Daniel Drocourt, Eric Perouzel, Gerard Tiraby, Thierry Lioux
  • Compositions of TLR7 and/or TLR8 agonists conjugated to lipids
    Patent number: 9458184
    Abstract: A conjugated compound of formula Q-Z—R4 wherein Q is a TLR7 and/or TLR8 agonist and Z—R4 is a lipid covalently linked to an amino acid or peptide coupled to a polyamine group, and a process for the manufacture of the conjugated compound, as well as a complex formed between the conjugated compound and a polyanionic molecule and a pharmaceutical composition containing the conjugated compound or complex. Also described is the use of the conjugated compound or complex in the treatment of infection, cancer or immune disorders or for use in vaccines.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: October 4, 2016
    Assignee: INVIVOGEN
    Inventors: Fabienne Vernejoul, Arnaud Debin, Daniel Drocourt, Eric Perouzel, Gerard Tiraby, Thierry Lioux
  • CONJUGATED TLR7 AND/OR TLR8 AND TLR2 AGONISTS
    Publication number: 20140141033
    Abstract: A conjugated compound of formula Q-Z—R4 wherein Q is a TLR7 and/or TLR8 agonist and Z—R4 is a TLR2 agonist, and the uses thereof in the treatment of infection, cancer or immune disorders or for use in vaccines.
    Type: Application
    Filed: March 15, 2013
    Publication date: May 22, 2014
    Applicant: CAYLA
    Inventors: Fabienne VERNEJOUL, Arnaud DEBIN, Daniel DROCOURT, Eric PEROUZEL, Gerard TIRABY, Thierry LIOUX
  • NOVEL COMPOSITIONS OF TLR7 AND/OR TLR8 AGONISTS CONJUGATED TO LIPIDS
    Publication number: 20130336996
    Abstract: A conjugated compound of formula Q-Z—R4 wherein Q is a TLR7 and/or TLR8 agonist and Z—R4 is a lipid covalently linked to an amino acid or peptide coupled to a polyamine group, and a process for the manufacture of the conjugated compound, as well as a complex formed between the conjugated compound and a polyanionic molecule and a pharmaceutical composition containing the conjugated compound or complex. Also described is the use of the conjugated compound or complex in the treatment of infection, cancer or immune disorders or for use in vaccines.
    Type: Application
    Filed: March 15, 2013
    Publication date: December 19, 2013
    Applicant: CAYLA
    Inventors: Fabienne VERNEJOUL, Arnaud DEBIN, Daniel DROCOURT, Eric PEROUZEL, Gerard TIRABY, Thierry LIOUX
  • Particulate complex for administering nucleic acid into a cell
    Publication number: 20030236207
    Abstract: A particulate complex including a nucleic acid and a biodegradable cationized polyhydroxylated molecule, wherein said molecule has a charge up to approximately 1.0 meq/g.
    Type: Application
    Filed: October 25, 2002
    Publication date: December 25, 2003
    Applicant: Biovector Therapeutics, S.A.
    Inventors: Arnaud Debin, Roger Kravtzoff, Marinette Moynier, Ignacio De Miguel, Olivier Balland, Philippe Pajot, Jocelyn Vaz Santiago, Paul von Hoegen
  • Particulate complex for adminstering nucleic acid into a cell
    Publication number: 20010046705
    Abstract: A particulate complex is provided comprising a particulate complex comprising a nucleic acid and a biodegradable cationized polyhydroxylated molecule, wherein the polyhydroxylated molecule has a charge up to approximately 1.0 meq/g.
    Type: Application
    Filed: December 22, 2000
    Publication date: November 29, 2001
    Inventors: Arnaud Debin, Roger Kravtzoff, Marinette Moynier, Ignacio De Miguel, Olivier Balland, Philippe Pajot, Jocelyn Vaz Santiago, Paul Von Hoegen