Patents by Inventor Arnd Wochner
Arnd Wochner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240050907Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.Type: ApplicationFiled: May 4, 2023Publication date: February 15, 2024Inventors: Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Bernd KRAUSE, Markus HORNUNG, Markus STORR, Heinrich BEHR, Werner BECK, Carina ZWEIGART, Reinhold BUCK, Philipp HERBST, Joachim LOERCHER, Arnd WOCHNER
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Publication number: 20230271146Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.Type: ApplicationFiled: May 4, 2023Publication date: August 31, 2023Inventors: Markus HORNUNG, Bernd KRAUSE, Markus STORR, Philipp HERBST, Arnd WOCHNER, Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Carina ZWEIGART, Joachim LOERCHER, Reinhold BUCK, Heinrich BEHR, Werner BECK
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Patent number: 11666868Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.Type: GrantFiled: February 1, 2022Date of Patent: June 6, 2023Assignee: GAMBRO LUNDIA ABInventors: Adriana Boschetti-De-Fierro, Manuel Voigt, Bernd Krause, Markus Hornung, Markus Storr, Heinrich Behr, Werner Beck, Carina Zweigart, Reinhold Buck, Philipp Herbst, Joachim Loercher, Arnd Wochner
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Patent number: 11666869Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.Type: GrantFiled: February 1, 2022Date of Patent: June 6, 2023Assignee: GAMBRO LUNDIA ABInventors: Markus Hornung, Bernd Krause, Markus Storr, Philipp Herbst, Arnd Wochner, Adriana Boschetti-De-Fierro, Manuel Voigt, Carina Zweigart, Joachim Loercher, Reinhold Buck, Heinrich Behr, Werner Beck
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Publication number: 20220339585Abstract: The present disclosure relates to a spinneret for producing hollow fiber membranes in a phase inversion process.Type: ApplicationFiled: December 21, 2020Publication date: October 27, 2022Inventors: Reinhold BUCK, Evelyn GROSSMANN, Markus HORNUNG, Markus LOEFFLER, Heinrich BEHR, Arnd WOCHNER, Carl-Philipp SCHEUERMANN
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Patent number: 11413384Abstract: The present disclosure relates to capillary dialyzers for blood purification, in particular, capillary dialyzers suitable for home hemodialysis systems.Type: GrantFiled: December 10, 2018Date of Patent: August 16, 2022Assignee: GAMBRO LUNDIA ABInventors: Joachim Loercher, Juergen Eichinger, Reinhold Buck, Arnd Wochner
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Publication number: 20220152563Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.Type: ApplicationFiled: February 1, 2022Publication date: May 19, 2022Inventors: Markus HORNUNG, Bernd KRAUSE, Markus STORR, Philipp HERBST, Arnd WOCHNER, Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Carina ZWEIGART, Joachim LOERCHER, Reinhold BUCK, Heinrich BEHR, Werner BECK
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Publication number: 20220152562Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.Type: ApplicationFiled: February 1, 2022Publication date: May 19, 2022Inventors: Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Bernd KRAUSE, Markus HORNUNG, Markus STORR, Heinrich BEHR, Werner BECK, Carina ZWEIGART, Reinhold BUCK, Philipp HERBST, Joachim LOERCHER, Arnd WOCHNER
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Patent number: 11273416Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.Type: GrantFiled: April 17, 2020Date of Patent: March 15, 2022Assignee: GAMBRO LUNDIA ABInventors: Adriana Boschetti-De-Fierro, Manuel Voigt, Bernd Krause, Markus Hornung, Markus Storr, Heinrich Behr, Werner Beck, Carina Zweigart, Reinhold Buck, Philipp Herbst, Joachim Loercher, Arnd Wochner
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Patent number: 11273417Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.Type: GrantFiled: April 17, 2020Date of Patent: March 15, 2022Assignee: GAMBRO LUNDIA ABInventors: Markus Hornung, Bernd Krause, Markus Storr, Philipp Herbst, Arnd Wochner, Adriana Boschetti-De-Fierro, Manuel Voigt, Carina Zweigart, Joachim Loercher, Reinhold Buck, Heinrich Behr, Werner Beck
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Publication number: 20220023803Abstract: The present invention relates to a continuous process for preparing permselective hollow fiber membranes being suitable e.g. for hemodialysis, hemodiafiltration and hemofiltration of blood which comprises a two-stage drying and tempering treatment of the hollow fiber membranes. According to a further aspect, the invention relates to a continuous process for drying permselective hollow fiber membranes on-line. The invention also relates to devices for on-line drying of permselective hollow fiber membranes.Type: ApplicationFiled: September 24, 2021Publication date: January 27, 2022Inventors: Ulrich BAUER, Reinhold BUCK, Juergen GRAF, Helmut HILDWEIN, Bernd KRAUSE, Markus STORR, Arnd WOCHNER
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Patent number: 11154820Abstract: The present invention relates to a continuous process for preparing permselective hollow fiber membranes being suitable e.g. for hemodialysis, hemodiafiltration and hemofiltration of blood which comprises a two-stage drying and tempering treatment of the hollow fiber membranes. According to a further aspect, the invention relates to a continuous process for drying permselective hollow fiber membranes on-line. The invention also relates to devices for on-line drying of permselective hollow fiber membranes.Type: GrantFiled: December 21, 2015Date of Patent: October 26, 2021Assignee: GAMBRO LUNDIA ABInventors: Ulrich Bauer, Reinhold Buck, Juergen Graf, Helmut Hildwein, Bernd Krause, Markus Storr, Arnd Wochner
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Patent number: 10888823Abstract: A semipermeable asymmetric hollow fiber membrane is provided, based on a hydrophobic polymer, such as polyethersulfone or polysulfone, and on a hydrophilic polymer, such as PVP. The PVP polymer comprises a high molecular weight component and a low molecular weight component. The membrane has a significantly improved permeability and selectivity, based on its structure, composition, and the method of manufacture of the membrane A process for manufacturing such a membrane by a solvent phase inversion spinning process is also provided.Type: GrantFiled: May 22, 2009Date of Patent: January 12, 2021Assignee: GAMBRO LUNDIA ABInventors: Reinhold Buck, Jenny Deibert, Arnd Wochner
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Publication number: 20200316533Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.Type: ApplicationFiled: April 17, 2020Publication date: October 8, 2020Inventors: Markus HORNUNG, Bernd KRAUSE, Markus STORR, Philipp HERBST, Arnd WOCHNER, Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Carina ZWEIGART, Joachim LOERCHER, Reinhold BUCK, Heinrich BEHR, Werner BECK
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Publication number: 20200276373Abstract: The present disclosure relates to capillary dialyzers for blood purification, in particular, capillary dialyzers suitable for home hemodialysis systems.Type: ApplicationFiled: December 10, 2018Publication date: September 3, 2020Inventors: Joachim LOERCHER, Juergen EICHINGER, Reinhold BUCK, Arnd WOCHNER
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Publication number: 20200269197Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.Type: ApplicationFiled: April 17, 2020Publication date: August 27, 2020Inventors: Adriana BOSCHETTI-DE-FIERRO, Manuel VOIGT, Bernd KRAUSE, Markus HORNUNG, Markus STORR, Heinrich BEHR, Werner BECK, Carina ZWEIGART, Reinhold BUCK, Philipp HERBST, Joachim LOERCHER, Arnd WOCHNER
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Patent number: 10661231Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.Type: GrantFiled: February 5, 2015Date of Patent: May 26, 2020Assignee: GAMBRO LUNDIA ABInventors: Adriana Boschetti-De-Fierro, Manuel Voigt, Bernd Krause, Markus Hornung, Markus Storr, Heinrich Behr, Werner Beck, Carina Zweigart, Reinhold Buck, Philipp Herbst, Joachim Loercher, Arnd Wochner
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Patent number: 10661230Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.Type: GrantFiled: February 5, 2015Date of Patent: May 26, 2020Assignee: GAMBRO LUNDIA ABInventors: Markus Hornung, Bernd Krause, Markus Storr, Philipp Herbst, Arnd Wochner, Adriana Boschetti-De-Fierro, Manuel Voigt, Carina Zweigart, Joachim Loercher, Reinhold Buck, Heinrich Behr, Werner Beck
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Patent number: 10022481Abstract: The present disclosure relates to capillary dialyzers for blood purification comprising from 85-95% crimped fibers and from 5-15% non-crimped fibers.Type: GrantFiled: June 19, 2014Date of Patent: July 17, 2018Assignee: GAMBRO LUNDIA ABInventors: Markus Hornung, Arnd Wochner, Reinhold Buck, Helmut Hildwein, Nikolaus Kanarjow
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Publication number: 20170368507Abstract: The present invention relates to a continuous process for preparing permselective hollow fiber membranes being suitable e.g. for hemodialysis, hemodiafiltration and hemofiltration of blood which comprises a two-stage drying and tempering treatment of the hollow fiber membranes. According to a further aspect, the invention relates to a continuous process for drying permselective hollow fiber membranes on-line. The invention also relates to devices for on-line drying of permselective hollow fiber membranes.Type: ApplicationFiled: December 21, 2015Publication date: December 28, 2017Inventors: Ulrich BAUER, Reinhold BUCK, Juergen GRAF, Helmut HILDWEIN, Bernd KRAUSE, Markus STORR, Arnd WOCHNER