Patents by Inventor Arne Huvar

Arne Huvar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human vanilloid receptor VR3 protein
    Patent number: 7186803
    Abstract: DNA encoding human VR1 receptor has been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Grant
    Filed: November 10, 2004
    Date of Patent: March 6, 2007
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Adrienne Elizabeth Dubin, Arne Huvar, Charles A. Glass, Mark G. Erlander
  • Methods of use of DNA encoding a human histamine receptor of the H3 subtype
    Patent number: 7179604
    Abstract: DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Grant
    Filed: December 2, 2003
    Date of Patent: February 20, 2007
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Timothy W. Lovenberg, Mark Erlander, Arne Huvar, Jayashree Pyati
  • Human 5-HT3-C protein
    Patent number: 7109296
    Abstract: DNA encoding human 5-HT3-C has been cloned and characterized. The recombinant protein is capable of forming biologically active human 5-HT3-C protein. The cDNA has been expressed in recombinant host cells that produce active recombinant protein. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: September 19, 2006
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Adrienne E. Dubin, Mark G. Erlander, Arne Huvar, Rene Huvar, Lukas K. Buehler
  • Human vanilloid receptor VR3 protein
    Patent number: 7094877
    Abstract: DNA encoding human VR1 receptor has been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Grant
    Filed: March 4, 2002
    Date of Patent: August 22, 2006
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Adrienne Elizabeth Dubin, Arne Huvar, Charles A. Glass, Mark G. Erlander
  • Human histamine receptor of the H3 subtype
    Patent number: 7049401
    Abstract: DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: May 23, 2006
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Timothy W. Lovenberg, Mark Erlander, Arne Huvar, Jayashree Pyati
  • DNA encoding a human subunit 5-HT3-C of the 5-HT3 serotonin receptor
    Publication number: 20050124795
    Abstract: DNA encoding human 5-HT3-C has been cloned and characterized. The recombinant protein is capable of forming biologically active human 5-HT3-C protein. The cDNA has been expressed in recombinant host cells that produce active recombinant protein. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Application
    Filed: September 12, 2003
    Publication date: June 9, 2005
    Inventors: Adrienne Dubin, Mark Erlander, Arne Huvar, Rene Huvar, Lukas Buehler
  • DNA encoding human vanilloid receptor VR3
    Publication number: 20050084897
    Abstract: DNA encoding human VR1 receptor has been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Application
    Filed: November 10, 2004
    Publication date: April 21, 2005
    Inventors: Adrienne Dubin, Arne Huvar, Charles Glass, Mark Erlander
  • Method of identifying compounds that modulate human histamine H3 receptor
    Patent number: 6855560
    Abstract: DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: February 15, 2005
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Timothy W. Lovenberg, Mark Erlander, Arne Huvar, Jayashree Pyati
  • DNA encoding a human histamine receptor of the H3 subtype
    Publication number: 20040156845
    Abstract: DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Application
    Filed: December 2, 2003
    Publication date: August 12, 2004
    Inventors: Timothy W. Lovenberg, Mark Erlander, Arne Huvar, Jayashree Pyati
  • DNA encoding human vanilloid receptor VR3
    Publication number: 20030032097
    Abstract: DNA encoding human VR1 receptor has been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Application
    Filed: March 4, 2002
    Publication date: February 13, 2003
    Inventors: Adrienne Elizabeth Dubin, Arne Huvar, Charles A. Glass, Mark G. Erlander
  • DNA encoding a human subunit 5-HT3-C of the 5-HT3 serotonin receptor
    Publication number: 20020137138
    Abstract: DNA encoding human 5-HT3-C has been cloned and characterized. The recombinant protein is capable of forming biologically active human 5-HT3-C protein. The cDNA has been expressed in recombinant host cells that produce active recombinant protein. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Application
    Filed: September 12, 2001
    Publication date: September 26, 2002
    Inventors: Adrienne E. Dubin, Mark G. Erlander, Arne Huvar, Rene Huvar, Lukas K. Buehler
  • DNA encoding human vanilloid receptor VR3
    Patent number: 6455278
    Abstract: DNA encoding human VR1 receptor has been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Grant
    Filed: February 8, 2000
    Date of Patent: September 24, 2002
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Adrienne Elizabeth Dubin, Arne Huvar, Charles A. Glass, Mark G. Erlander
  • DNA encoding a human histamine receptor of the H3 subtype
    Patent number: 6437100
    Abstract: DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: August 20, 2002
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Timothy W. Lovenberg, Mark Erlander, Arne Huvar, Jayashree Pyati
  • DNA encoding a human histamine receptor of the H3 subtype
    Patent number: 6413743
    Abstract: DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: July 2, 2002
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Timothy W. Lovenberg, Mark Erlander, Arne Huvar, Jayashree Pyati
  • DNA encoding a human subunit 5-HT3-C of the 5-HT3 serotonin receptor
    Patent number: 6365370
    Abstract: DNA encoding human 5-HT3-C has been cloned and characterized. The recombinant protein is capable of forming biologically active human 5-HT3-C protein. The cDNA has been expressed in recombinant host cells that produce active recombinant protein. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Grant
    Filed: September 1, 1999
    Date of Patent: April 2, 2002
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Adrienne E. Dubin, Mark G. Erlander, Arne Huvar, Rene Huvar, Lukas K. Buehler
  • DNA encoding as human histamine receptor of the H3 subtype
    Patent number: 6136559
    Abstract: DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
    Type: Grant
    Filed: October 7, 1998
    Date of Patent: October 24, 2000
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Timothy W. Lovenberg, Mark Erlander, Arne Huvar, Jayashree Pyati