Abstract: The present invention provides an improved pharmaceutical composition for storage and administration comprising (a) a bispecific antibody construct comprising a first domain binding to a target cell surface antigen and a second domain binding to a second antigen, wherein the bispecific antibody construct is present at a concentration in the range from about 0.5 ?g/ml to 20 mg/ml, (b) a preservative at a concentration effective to inhibit the growth of microbes, and (c) a diluent wherein bispecific antibody construct is stable and recoverable.

Abstract: The present invention concerns an apparatus for ultrasonic welding of at least two material webs comprising a processing sonotrode which can be excited with an ultrasonic vibration, a processing counterpart tool and a material web guide which is so designed that the material web can be passed through between the processing sonotrode and the processing counterpart tool, in which there is provided a device for heating at least one material web prior to the welding operation. To provide an ultrasonic welding apparatus which avoids the stated disadvantages and which nonetheless provides a high processing speed it is proposed according to the invention that the device for preheating at least one material web has a preheating sonotrode which can be excited with an ultrasonic vibration.

Abstract: The present invention concerns an apparatus for ultrasonic welding of at least two material webs comprising a processing sonotrode which can be excited with an ultrasonic vibration, a processing counterpart tool and a material web guide which is so designed that the material web can be passed through between the processing sonotrode and the processing counterpart tool, in which there is provided a device for heating at least one material web prior to the welding operation. To provide an ultrasonic welding apparatus which avoids the stated disadvantages and which nonetheless provides a high processing speed it is proposed according to the invention that the device for preheating at least one material web has a preheating sonotrode which can be excited with an ultrasonic vibration.

Abstract: The invention relates to an ultrasonic welding apparatus for ultrasonic machining of a material, having at least two sonotrodes and a converter device, which converts an electrical AC voltage into an ultrasonic vibration and sets the at least two sonotrodes in ultrasonic vibration, the at least two sonotrodes being arranged in such a manner that the material to be machined is arranged between them during machining and can at the same time be machined by the at least two sonotrodes. To specify an ultrasonic welding apparatus that allows effective material machining without an undesirable interaction occurring between the two sonotrodes, the converter device according to the invention excites the first sonotrode at a frequency fs1 and the second sonotrode at a frequency fs2, fs2 being greater than fs1.

Abstract: The invention relates to an ultrasonic welding apparatus for ultrasonic machining of a material, having at least two sonotrodes and a converter device, which converts an electrical AC voltage into an ultrasonic vibration and sets the at least two sonotrodes in ultrasonic vibration, the at least two sonotrodes being arranged in such a manner that the material to be machined is arranged between them during machining and can at the same time be machined by the at least two sonotrodes. To specify an ultrasonic welding apparatus that allows effective material machining without an undesirable interaction occurring between the two sonotrodes, the converter device according to the invention excites the first sonotrode at a frequency fs1 the second sonotrode at a frequency fs2, fs2 being greater than fs1.

Abstract: Tube laminate film (22) for the production of a tube packaging having at least one plastics layer (36, 38) and also at least one barrier layer (30) is characterised in that the barrier layer (30) is an oriented barrier layer (30).

Abstract: A device for processing workpieces uses ultrasound, with an resonant system comprising an ultrasound generator, an ultrasound sonotrode, and an anvil, wherein a workpiece is processed between the anvil and the ultrasound sonotrode. The ultrasound generator comprises a regulation means which has a regulation member connected upstream of the ultrasound generator to receive a feedback signal from the resonant system and to generate a regulation variable which is supplied to the ultrasound generator. A connecting point is provided between the regulation member and the ultrasound generator, at which the regulation variable of the regulation member is linked to a process variable from the processing procedure.

Abstract: A device for processing workpieces uses ultrasound, with an resonant system comprising an ultrasound generator, an ultrasound sonotrode, and an anvil, wherein a workpiece is processed between the anvil and the ultrasound sonotrode. The ultrasound generator comprises a regulation means which has a regulation member connected upstream of the ultrasound generator to receive a feedback signal from the resonant system and to generate a regulation variable which is supplied to the ultrasound generator. A connecting point is provided between the regulation member and the ultrasound generator, at which the regulation variable of the regulation member is linked to a process variable from the processing procedure.

Abstract: Container (10), especially a flexible tubular-pouch-like and/or can-like packaging container, preferably a round pouch, having a container body (20) and a lid part (30) and also, optionally, a base part (40), which is made at least in part from a film, especially a composite film, or a laminate, wherein the container has at least one peel tab (50), by means of which the at least one withdrawal (60) and/or venting opening is covered over.

Abstract: A device for processing workpieces uses ultrasound, with an resonant system comprising an ultrasound generator, an ultrasound sonotrode, and an anvil, wherein a workpiece is processed between the anvil and the ultrasound sonotrode. The ultrasound generator comprises a regulation means which has a regulation member connected upstream of the ultrasound generator to receive a feedback signal from the resonant system and to generate a regulation variable which is supplied to the ultrasound generator. A connecting point is provided between the regulation member and the ultrasound generator, at which the regulation variable of the regulation member is linked to a process variable from the processing procedure.

Abstract: An apparatus for continuously bonding and/or welding material webs by means of ultrasound, having an ultrasonic horn configured as a rotating roller, an anvil radially opposite the rotating roller, an amplitude transformer set axially on the rotating roller, an ultrasonic converter attached to the amplitude transformer with an energy supply, where the length 1 of the rotating roller equals a ?/2 wave or a multiple thereof (1=x·?/2).

Abstract: An apparatus for continuously bonding and/or welding material webs by means of ultrasound, having an ultrasonic horn configured as a rotating roller, an anvil radially opposite the rotating roller, an amplitude transformer set axially on the rotating roller, an ultrasonic converter attached to the amplitude transformer with an energy supply, where the length l of the rotating roller equals a ?/2 wave or a multiple thereof (l=x·?/2).

Abstract: A sound damping element contains an inner wall and an outer wall, between which a cavity filled with absorption material is present, which are joined to one another. At longitudinal edges of the element, bent-away profile portions are disposed so that a junction with a similarly configured adjacent sound damping element can be made. The sound damping element is to be improved such that, with low production and material cost, a seal for preventing gas from passing through the element is achieved. Easy manipulation in assembly is possible, and the individual sound damping elements can be joined together without problems and, if necessary, separated from one another. At least one profile portion has a section such that at least a portion of a chamber is formed. At least in the portion of this chamber, a sealing element is disposed. Sealing is accomplished by this sealing element with respect to the adjacent second sound damping element.