Abstract: A tissue fixation device includes an elongated body defining a longitudinal axis and including a proximal end and a distal end. At least two barbed segments diverge distally away from the distal end of the elongated body and a pledget is disposed at distal ends of the barbed segments. The elongated body, barbed segments, and pledget are provided in a variety of configurations depending upon the performance requirements desired of the tissue fixation device for the envisaged application of use.

Abstract: A tissue fixation device includes a barbed body in a general figure eight configuration including a first loop intersecting a second loop. The barbed body may include a third loop at a proximal end thereof, and/or a pledget at a distal end thereof. The configuration of the tissue fixation device may vary depending upon the performance requirements desired of the tissue fixation device for the envisaged application of use.

Abstract: A tissue fixation device includes an elongated body extending between a distal portion including a barbed loop, and a proximal portion including a blunt tip. The elongated body, proximal portion, and distal portion are provided in a variety of configurations depending upon the performance requirements desired of the tissue fixation device for the envisaged application of use.

Abstract: A tissue fixation device includes an elongated body extending between a proximal portion and a distal portion including a plurality of barbed loops. The elongated body, proximal portion, and distal portion are provided in a variety of configurations depending upon the performance requirements desired of the tissue fixation device for the envisaged application of use.

Abstract: A closure device for port site closure is provided. The closure device includes an end effector having a top surface and a bottom surface. A stem extends upwardly from a midsection of the top surface of the end effector. The stem has a free end, a distal end, and a middle portion therebetween. An attachment member extends from the distal end of the stem and is fixedly attached to the top surface of the end effector. The attachment member has a width smaller than a width of the distal end. At least one notch is defined by a gap between the distal end of the stem and the top surface of the end effector.

Abstract: An applicator for use in tissue repair is provided. The applicator includes a base configured to dispense a material and an applicator tip operably connected to the base. The applicator tip includes a body having a distal end configured to engage a tissue defect and a mold disposed about the body configured to engage tissue about the tissue defect. The mold is configured to be selectively positioned about the distal end of the body between at least a first position and a second position to deposit material to form at least a first layer and a second layer. Also provided are applicator tips, methods and kits for tissue repair.

Abstract: The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.

Abstract: Biocompatible wound closure devices including an elongate body and a plug member are useful for wound repair.

Abstract: An osteochondral plug includes a first scaffold and a second scaffold. The first scaffold may be a solid scaffold containing one or more pendant reactive functional groups. The second scaffold capable of reacting with the one or more pendant reactive functional groups of the first scaffold.

Abstract: Biocompatible wound closure devices including an elongate body and a plug member are useful for wound repair. A wound closure device includes an elongate body defining a longitudinal axis and having a proximal end and a distal end, and a plug member having a tissue facing surface and including a first shaped section and a second shaped section, each of the first and second shaped sections having an abutment surface. The first and second shaped sections are movable about a hinge between a collapsed position in which the abutment surfaces extend away from the longitudinal axis of the elongate body and a deployed position in which the abutment surfaces abut and are substantially aligned with the longitudinal axis of the elongate body, the abutment surfaces controlling a deployed angle of the tissue facing surface of the plug member with respect to the elongate body.

Abstract: A surgical portal apparatus includes a sleeve having a proximal end and a distal end that extends along a longitudinal axis, and a surgical tape. The sleeve includes an inner wall defining an internal longitudinal passageway dimensioned for permitting passage of a surgical object therethrough and an outer wall configured for positioning against tissue. The inner and outer walls define at least a partial annular space therebetween, the annular space being in fluid communication with an opening in the outer wall. The surgical tape includes a body portion retained within the annular space of the sleeve and a leading tab extendable through the opening in the outer wall of the sleeve. The surgical tape has a first surface and a second surface, each of the first and second surfaces having at least one of tissue reactive functional groups and self-reactive functional groups.

Abstract: Medical devices possessing coatings are provided. The coatings include at least one polyelectrolyte, capable of changing the surface charge of the device to which they are applied. The polyelectrolytes permit attachment of charged bioactive agents thereto. Multiple polyelectrolytes, possessing opposite charges, may be sequentially applied to produce a medical device having multiple layers. Methods for forming such devices are also provided.

Abstract: An applicator tip for use with a fluid applicator includes a base configured for releasable engagement with a fluid applicator at a proximal end of the base. The base includes a chamber defined therein configured for retaining a mixing component therein. One or more penetrable members are disposed within the base to at least partially encloses the chamber to retain the mixing component therein. A shaft extends distally from the base and defines a longitudinal axis. The shaft has a lumen extending therethrough configured for passage of a fluid therethrough. Upon penetration of the penetrable member, fluid from the fluid applicator flows into the chamber such that the fluid and the mixing component form a mixture to be applied.

Abstract: A surgical instrument includes an elongated tubular member having a proximal end and a distal end. At least a portion of the elongated tubular member is resiliently deformable from an at-rest configuration. The elongated tubular member includes a camera assembly disposed therein. An outer shaft defining a lumen extending therethrough is positioned annularly about the elongated tubular member. At least one of the outer shaft and the elongated tubular member is moveable with respect to the other between a substantially overlapping position wherein the elongated tubular member is deformed to conform to the shape of the outer shaft, and a displaced position wherein at least a portion of the elongated tubular member extends distally from a distal end of the outer shaft. In the displaced position, the portion of the elongated tubular member extending from the outer shaft returns, or reforms back to the at-rest configuration.

Abstract: An applicator tip for use with a fluid applicator includes a base configured for releasable engagement with a fluid applicator at a proximal end of the base. The base includes a chamber defined therein configured for retaining a mixing component therein. One or more penetrable members are disposed within the base to at least partially encloses the chamber to retain the mixing component therein. A shaft extends distally from the base and defines a longitudinal axis. The shaft has a lumen extending therethrough configured for passage of a fluid therethrough. Upon penetration of the penetrable member, fluid from the fluid applicator flows into the chamber such that the fluid and the mixing component form a mixture to be applied.

Abstract: A surgical instrument includes an elongated tubular member defining a longitudinal axis and having a lumen extending therethrough. A light source is disposed within the elongated tubular member. The light source is configured to emit light from a distal end of the elongated tubular member. A mirror assembly is coupled to a distal end of the elongated tubular member. The mirror assembly is moveable between a retracted position and an extended position. In the retracted position, the mirror assembly is positioned adjacent an outer surface of the elongated tubular member. In the extended position, the mirror assembly extends distally from the elongated tubular member to re-direct light emitted by the light source.

Abstract: Applicator tips in accordance with the present disclosure include a body portion and dispensing tip. The body portion includes a proximal end having an inlet adapted for fluid communication with a fluid source, a distal end including an opening, and a mixing chamber disposed therebetween. The mixing chamber includes at least one mixing ball and at least one biologically active agent disposed therein. The dispensing tip defines a lumen therethrough. The lumen is in fluid communication with the opening of the distal end of the body portion and includes an outlet for passage of a fluid therethrough.

Abstract: The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.

Abstract: An applicator for use in tissue repair is provided. The applicator includes a base configured to dispense a material and an applicator tip operably connected to the base. The applicator tip includes a body having a distal end configured to engage a tissue defect and a mold disposed about the body configured to engage tissue about the tissue defect. The mold is configured to be selectively positioned about the distal end of the body between at least a first position and a second position to deposit material to form at least a first layer and a second layer. Also provided are applicator tips, methods and kits for tissue repair.

Abstract: An osteochondral plug includes a first scaffold and a second scaffold. The first scaffold may be a solid scaffold containing one or more pendant reactive functional groups.