Patents by Inventor Arrin Katz
Arrin Katz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220088561Abstract: A method of registering a location of a dispenser array in relation to a microfluidic array is provided. One of the dispenser array and the microfluidic array can be movable in relation to the frame, and the other can be fixed relative to the frame. Their relative positions can be identified by a set of coordinates. Identification of a fiducial marker can occur in a manner permitting the fiducial reference to appear in a first position of a field of view of a first camera when the dispenser array or the microfluidic array is in an alignment position. Quantities related to a vector displacement from the alignment position to a fixed position on the microfluidic array or the dispenser array can be identified. Quantities determined can be used to guide positioning of the dispenser array relative to the microfluidic array.Type: ApplicationFiled: October 19, 2021Publication date: March 24, 2022Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Colin BRENAN, Jamie CHO, Javier GARCIA, Robert HESS, Tanya KANIGAN, Arrin KATZ, Namyong KIM, John LINTON, Shailesh SRIVASTAVA, Karl YODER
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Patent number: 11154834Abstract: A differentially coated device for conducting a plurality of nano-volume specified reactions, the device comprising a platen having at least one exterior surface modified to a specified physicochemical property, a plurality of nano-volume channels, each nanovolume channel having at least one interior surface in communication with the at least one exterior surface. Methods for preparing and using such devices are also provided, as well as a method of registering a location of a dispenser array in relation to a microfluidic array. Quantities related to a vector displacement from the alignment position to a fixed position on the one of the dispenser array and the microfluidic array is determined. The quantities thus determined are used to guide positioning of the dispenser array relative to the microfluidic array.Type: GrantFiled: February 25, 2019Date of Patent: October 26, 2021Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Colin Brenan, Jamie Cho, Javier Garcia, Robert Hess, Tanya Kanigan, Arrin Katz, Namyong Kim, John Linton, Shailesh Srivastava, Karl Yoder
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Publication number: 20200055016Abstract: A differentially coated device for conducting a plurality of nano-volume specified reactions, the device comprising a platen having at least one exterior surface modified to a specified physicochemical property, a plurality of nano-volume channels, each nano-volume channel having at least one interior surface in communication with the at least one exterior surface that is selectively coated with an optionally dissolvable coating agent physisorbed to at least one interior surface, wherein the optionally dissolvable coating agent comprises a coating agent and a first component for the plurality of specified reactions. Methods for preparing and using such devices are also provided, as well as a method of registering a location of a dispenser array in relation to a microfluidic array. A first one of the dispenser array and the microfluidic array is movable in relation to the frame, and the other of the first one of the dispenser array and the microfluidic array is fixed relative to the frame.Type: ApplicationFiled: February 25, 2019Publication date: February 20, 2020Inventors: Colin BRENAN, Jamie CHO, Javier GARCIA, Robert HESS, Tanya Kanigan, Arrin Katz, Namyong KIM, John LINTON, Shailesh SRIVASTAVA, Karl Yoder
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Patent number: 10213761Abstract: A differentially coated device for conducting a plurality of nano-volume specified reactions, the device comprising a platen having at least one exterior surface modified to a specified physicochemical property, a plurality of nano-volume channels, each nano-volume channel having at least one interior surface in communication with the at least one exterior surface that is selectively coated with an optionally dissolvable coating agent physisorbed to at least one interior surface, wherein the optionally dissolvable coating agent comprises a coating agent and a first component for the plurality of specified reactions. Methods for preparing and using such devices are also provided, as well as a method of registering a location of a dispenser array in relation to a microfluidic array. A first one of the dispenser array and the microfluidic array is movable in relation to the frame, and the other of the first one of the dispenser array and the microfluidic array is fixed relative to the frame.Type: GrantFiled: June 9, 2014Date of Patent: February 26, 2019Assignee: Life Technologies CorporationInventors: Colin J. H. Brenan, Jamie Cho, Javier Garcia, Robert Hess, Tanya S. Kanigan, Arrin Katz, Namyong Kim, John Linton, Shailesh Srivastava, Karl Yoder
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Patent number: 9428800Abstract: A system for holding at least one of sample and reagent for analysis. The system includes a pair of parallel covers, at least one of which is light transmissive, of which pair a light transmissive cover forms a top, and of which pair the other forms a bottom. A frame is disposed between the covers to define, in relation to the covers, an interior volume. The frame and the covers are associated with one another to form a case, the case being substantially tight to liquids. A microfluidic array is disposed in the interior volume. The array includes a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces, the through-holes containing at least one of sample and reagent.Type: GrantFiled: March 3, 2014Date of Patent: August 30, 2016Assignee: Life Technologies CorporationInventors: John Linton, Arrin Katz, Colin Brenan, Karl Yoder, Robert Hess, Leila Madrone, Robert Ellis, Tanya Kanigan, Kristine Friesen, Thomas Morrison, Javier Garcia
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Publication number: 20150011436Abstract: A differentially coated device for conducting a plurality of nano-volume specified reactions, the device comprising a platen having at least one exterior surface modified to a specified physicochemical property, a plurality of nano-volume channels, each nano-volume channel having at least one interior surface in communication with the at least one exterior surface that is selectively coated with an optionally dissolvable coating agent physisorbed to at least one interior surface, wherein the optionally dissolvable coating agent comprises a coating agent and a first component for the plurality of specified reactions. Methods for preparing and using such devices are also provided, as well as a method of registering a location of a dispenser array in relation to a microfluidic array. A first one of the dispenser array and the microfluidic array is movable in relation to the frame, and the other of the first one of the dispenser array and the microfluidic array is fixed relative to the frame.Type: ApplicationFiled: June 9, 2014Publication date: January 8, 2015Inventors: Colin J. H. Brenan, Jamie Cho, Javier Garcia, Robert Hess, Tanya S. Kanigan, Arrin Katz, Namyong Kim, John Linton, Shailesh Srivastava, Karl Yoder
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Publication number: 20140179566Abstract: A system for holding at least one of sample and reagent for analysis. The system includes a pair of parallel covers, at least one of which is light transmissive, of which pair a light transmissive cover forms a top, and of which pair the other forms a bottom. A frame is disposed between the covers to define, in relation to the covers, an interior volume. The frame and the covers are associated with one another to form a case, the case being substantially tight to liquids. A microfluidic array is disposed in the interior volume. The array includes a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces, the through-holes containing at least one of sample and reagent.Type: ApplicationFiled: March 3, 2014Publication date: June 26, 2014Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: John LINTON, Arrin Katz, Colin Brenan, Karl Yoder, Robert Hess, Leila Hasan, Robert Ellis, Tanya Kanigan, Kristine Friesen, Thomas Morrison, Javier Garcia
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Patent number: 8697452Abstract: A system for holding at least one of sample and reagent for analysis. The system includes a pair of parallel covers, at least one of which is light transmissive, of which pair a light transmissive cover forms a top, and of which pair the other forms a bottom. A frame is disposed between the covers to define, in relation to the covers, an interior volume. The frame and the covers are associated with one another to form a case, the case being substantially tight to liquids. A microfluidic array is disposed in the interior volume. The array includes a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces, the through-holes containing at least one of sample and reagent.Type: GrantFiled: June 8, 2012Date of Patent: April 15, 2014Assignee: Life Technologies CorporationInventors: John Linton, Arrin Katz, Colin Brenan, Karl Yoder, Robert Hess, Leila Hasan, Robert Ellis, Tanya Kanigan, Kristine Friesen, Thomas Morrison, Javier Garcia
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Patent number: 8677808Abstract: One embodiment of the invention provides a sample injection system including a vacuum source, a conduit in communication with the vacuum source, a fluid sensor configured to detect the presence of the fluid in the conduit, a sample loop in communication with the conduit; and a sipper in communication with the sample loop.Type: GrantFiled: November 3, 2008Date of Patent: March 25, 2014Assignee: Agilent Technologies, Inc.Inventors: Can C. Ozbal, Arrin Katz, Maxine Jonas
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Patent number: 8414774Abstract: Aspects of the invention provide systems and methods for high-throughput screening of fluidic samples. In some embodiments, two chromatography columns are utilized in series. The first chromatography column can have a high affinity for phosphorylated compounds while the second chromatography column has a high affinity for one or more analytes of interest.Type: GrantFiled: September 15, 2009Date of Patent: April 9, 2013Assignee: Agilent Technologies, Inc.Inventors: William A. LaMarr, Can C. Ozbal, Arrin Katz, Donald Green
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Publication number: 20120245038Abstract: A system for holding at least one of sample and reagent for analysis. The system includes a pair of parallel covers, at least one of which is light transmissive, of which pair a light transmissive cover forms a top, and of which pair the other forms a bottom. A frame is disposed between the covers to define, in relation to the covers, an interior volume. The frame and the covers are associated with one another to form a case, the case being substantially tight to liquids. A microfluidic array is disposed in the interior volume. The array includes a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces, the through-holes containing at least one of sample and reagent.Type: ApplicationFiled: June 8, 2012Publication date: September 27, 2012Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: John Linton, Karl Yoder, Robert Hess, Leila Hasan, Robert Ellis, Tanya S. Kanigan, Kristine Friesen, Arrin Katz, Colin Brenan, Tom Morrison, Javier Garcia
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Publication number: 20110290731Abstract: Aspects of the invention provide cartridge changers and methods utilizing the same. One aspect of the invention provides a cartridge changer for a plurality of cartridges. The cartridge changer includes a cartridge holder having a plurality of receptacles each adapted to receive one of the plurality of cartridges and a pair of fittings adapted to releasably engage one of the plurality of cartridges.Type: ApplicationFiled: May 26, 2011Publication date: December 1, 2011Inventors: Can C. Ozbal, Arrin Katz, Donald Green, Eduard Vernikov
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Publication number: 20110003699Abstract: A system for thermal cycling a plurality of samples. The system includes a case having a fluid-tight cavity defining an interior volume. A microfluidic array is disposed in the interior volume, the array including a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces. A thermal cycler having at least one thermally controlled surface is adapted to thermally contact the case.Type: ApplicationFiled: December 18, 2009Publication date: January 6, 2011Applicant: BioTrove, Inc.Inventors: Karl Yoder, Colin Brenan, John Linton, Leila Hasan, Robert Ellis, Arrin Katz, Tom Morrison, Jorge Fonseca
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Publication number: 20100256010Abstract: One embodiment of the invention provides a sample injection system including a vacuum source, a conduit in communication with the vacuum source, a fluid sensor configured to detect the presence of the fluid in the conduit, a sample loop in communication with theType: ApplicationFiled: November 3, 2008Publication date: October 7, 2010Applicant: BIOCIUS LIFE SCIENCES, INC.Inventors: Can C. Ozbal, Arrin Katz, Maxine Jonas
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Patent number: 7682565Abstract: A system for holding at least one of sample and reagent for analysis. The system includes a pair of parallel covers, at least one of which is light transmissive, of which pair a light transmissive cover forms a top, and of which pair the other forms a bottom. A frame is disposed between the covers to define, in relation to the covers, an interior volume. The frame and the covers are associated with one another to form a case, the case being substantially tight to liquids. A microfluidic array is disposed in the interior volume. The array includes a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces, the through-holes containing at least one of sample and reagent.Type: GrantFiled: December 22, 2003Date of Patent: March 23, 2010Assignee: BioTrove, Inc.Inventors: John Linton, Karl Yoder, Robert Hess, Leila Hasan, Robert Ellis, Tanya S. Kanigan, Kristine Friesen, Arrin Katz, Colin Brenan, Tom Morrison, Javier Garcia
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Publication number: 20100024527Abstract: Aspects of the invention provide systems and methods for high-throughput screening of fluidic samples. In some embodiments, two chromatography columns are utilized in series. The first chromatography column can have a high affinity for phosphorylated compounds while the second chromatography column has a high affinity for one or more analytes of interest.Type: ApplicationFiled: September 15, 2009Publication date: February 4, 2010Applicant: BIOTROVE, INC.Inventors: William A. LaMarr, Can C. Ozbal, Arrin Katz, Donald Green
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Publication number: 20090062134Abstract: A method of conducting an assay on a plurality of samples is provided. The method includes the steps of performing an assay at each sample site in a sample array having greater than 100 sample sites simultaneously illuminating each sample site using one or more LEDs, and simultaneously imaging each of the sample sites to produce imaging data pertinent to the optical effect of each site. Each assay provides an optical effect.Type: ApplicationFiled: October 3, 2008Publication date: March 5, 2009Applicant: BIOTROVE, INC.Inventors: John Linton, Karl Yoder, Robert Hess, Leila Hasan, Robert Ellis, Tanya S. Kanigan, Kristine Friesen, Arrin Katz, Colin Brenan, Tom Morrison, Javier Garcia
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Publication number: 20090062152Abstract: A thermal cycling device and a method of thermal cycling are provided. A thermal cycling device includes a fluid device system, a case, and a cycling head. The fluid delivery system develops a flow of controlled-temperature fluid. The case has a fluid-tight cavity for holding a microfluidic array. The array includes a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces. The cycling head holds the case and delivers the flow of fluid over the case.Type: ApplicationFiled: October 1, 2008Publication date: March 5, 2009Applicant: BIOTROVE, INC.Inventors: John Linton, Karl Yoder, Robert Hess, Leila Hasan, Robert Ellis, Tanya S. Kanigan, Kristine Friesen, Arrin Katz, Colin Brenan, Tom Morrison, Javier Garcia
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Publication number: 20060105453Abstract: A differentially coated device for conducting a plurality of nano-volume specified reactions, the device comprising a platen having at least one exterior surface modified to a specified physicochemical property, a plurality of nano-volume channels, each nano-volume channel having at least one interior surface in communication with the at least one exterior surface that is selectively coated with an optionally dissolvable coating agent physisorbed to at least one interior surface, wherein the optionally dissolvable coating agent comprises a coating agent and a first component for the plurality of specified reactions. Methods for preparing and using such devices are also provided, as well as a method of registering a location of a dispenser array in relation to a microfluidic array. A first one of the dispenser array and the microfluidic array is movable in relation to the frame, and the other of the first one of the dispenser array and the microfluidic array is fixed relative to the frame.Type: ApplicationFiled: August 4, 2005Publication date: May 18, 2006Inventors: Colin Brenan, Jamie Cho, Javier Garcia, Robert Hess, Tanya Kanigan, Arrin Katz, Namyong Kim, John Linton, Shailesh Srivastava, Karl Yoder
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Publication number: 20060094108Abstract: A system for thermal cycling a plurality of samples. The system includes a case having a fluid-tight cavity defining an interior volume. A microfluidic array is disposed in the interior volume, the array including a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces. A thermal cycler having at least one thermally controlled surface is adapted to thermally contact the case.Type: ApplicationFiled: September 15, 2005Publication date: May 4, 2006Inventors: Karl Yoder, Colin Brenan, John Linton, Leila Hasan, Robert Ellis, Arrin Katz, Tom Morrison, Jorge Fonseca