Patents by Inventor Arthur E. Colvin, Jr.
Arthur E. Colvin, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11627728Abstract: A device for detecting a presence or concentration of an analyte on an egg shell or in an egg, the device comprising an emitter, wherein the emitter is configured to emit light into the egg, a detector, wherein the detector is configured to receive light emitted from an indicator molecule within the egg, a controller configured to analyze a change in a detectable quality of the indicator molecule based on the presence or concentration of the analyte.Type: GrantFiled: February 23, 2018Date of Patent: April 18, 2023Assignee: RYSHENS LTD.Inventor: Arthur E. Colvin, Jr.
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Patent number: 10905355Abstract: Systems and methods for automatically triggering wireless power and data exchange between an external reader and an implanted sensor. The implanted sensor may measure the strength of an electrodynamic field received wirelessly from the reader and convey field strength data based on the measured strength of the received electrodynamic field to the reader. If the field strength data indicates that the strength of an electrodynamic field received by the sensor is sufficient for the implanted sensor to perform an analyte measurement, the reader may convey an analyte measurement command to the sensor, which may execute the analyte measurement command and convey measurement information back to the reader. The systems and methods may trigger the analyte measurement as the reader transiently passes within sufficient range/proximity to the implant (or vice versa).Type: GrantFiled: September 17, 2019Date of Patent: February 2, 2021Assignee: Senseonics, IncorporatedInventors: Arthur E. Colvin, Jr., Andrew DeHennis
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Patent number: 10674937Abstract: An implantable device with in vivo functionality, where the functionality of the device is negatively affected by ROS typically associated with inflammation reaction as well as chronic foreign body response as a result of tissue injury, is at least partially surrounded by a protective material, structure, and/or a coating that prevents damage to the device from any inflammation reactions. The protective material, structure, and/or coating is a biocompatible metal, preferably silver, platinum, palladium, gold, manganese, or alloys or oxides thereof that decomposes reactive oxygen species (ROS), such as hydrogen peroxide, and prevents ROS from oxidizing molecules on the surface of or within the device. The protective material, structure, and/or coating thereby prevents ROS from degrading the in vivo functionality of the implantable device.Type: GrantFiled: June 15, 2017Date of Patent: June 9, 2020Assignee: Senseonics, IncorporatedInventors: Arthur E. Colvin, Jr., Hui Jiang
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Patent number: 10662333Abstract: The invention relates to a porphyrin time domain indicator. The indicator may be used for detection of a particular analyte in vivo or in vitro. The indicator may be used for detection of glucose in vivo or in vitro.Type: GrantFiled: June 16, 2017Date of Patent: May 26, 2020Assignee: Profusa, Inc.Inventor: Arthur E. Colvin, Jr.
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Publication number: 20200015705Abstract: Systems and methods for automatically triggering wireless power and data exchange between an external reader and an implanted sensor. The implanted sensor may measure the strength of an electrodynamic field received wirelessly from the reader and convey field strength data based on the measured strength of the received electrodynamic field to the reader. If the field strength data indicates that the strength of an electrodynamic field received by the sensor is sufficient for the implanted sensor to perform an analyte measurement, the reader may convey an analyte measurement command to the sensor, which may execute the analyte measurement command and convey measurement information back to the reader. The systems and methods may trigger the analyte measurement as the reader transiently passes within sufficient range/proximity to the implant (or vice versa).Type: ApplicationFiled: September 17, 2019Publication date: January 16, 2020Applicant: Senseonics, IncorporatedInventors: Arthur E. Colvin, JR., Andrew DeHennis
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Publication number: 20190352510Abstract: The invention relates to a porphyrin time domain indicator. The indicator may be used for detection of a particular analyte in vivo or in vitro. The indicator may be used for detection of glucose in vivo or in vitro.Type: ApplicationFiled: June 16, 2017Publication date: November 21, 2019Applicant: Profusa, Inc.Inventor: Arthur E. COLVIN, JR.
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Publication number: 20190069804Abstract: Systems and methods for automatically triggering wireless power and data exchange between an external reader and an implanted sensor. The implanted sensor may measure the strength of an electrodynamic field received wirelessly from the reader and convey field strength data based on the measured strength of the received electrodynamic field to the reader. If the field strength data indicates that the strength of an electrodynamic field received by the sensor is sufficient for the implanted sensor to perform an analyte measurement, the reader may convey an analyte measurement command to the sensor, which may execute the analyte measurement command and convey measurement information back to the reader. The systems and methods may trigger the analyte measurement as the reader transiently passes within sufficient range/proximity to the implant (or vice versa).Type: ApplicationFiled: July 30, 2018Publication date: March 7, 2019Applicant: Senseonics, IncorporatedInventors: Arthur E. Colvin, JR., Andrew DeHennis
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Patent number: 10034619Abstract: Systems and methods for automatically triggering wireless power and data exchange between an external reader and an implanted sensor. The implanted sensor may measure the strength of an electrodynamic field received wirelessly from the reader and convey field strength data based on the measured strength of the received electrodynamic field to the reader. If the field strength data indicates that the strength of an electrodynamic field received by the sensor is sufficient for the implanted sensor to perform an analyte measurement, the reader may convey an analyte measurement command to the sensor, which may execute the analyte measurement command and convey measurement information back to the reader. The systems and methods may trigger the analyte measurement as the reader transiently passes within sufficient range/proximity to the implant (or vice versa).Type: GrantFiled: February 10, 2017Date of Patent: July 31, 2018Assignee: Senseonics, IncorporatedInventors: Arthur E. Colvin, Jr., Andrew DeHennis
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Publication number: 20180146885Abstract: An implantable device with in vivo functionality, where the functionality of the device is negatively affected by ROS typically associated with inflammation reaction as well as chronic foreign body response as a result of tissue injury, is at least partially surrounded by a protective material, structure, and/or a coating that prevents damage to the device from any inflammation reactions. The protective material, structure, and/or coating is a biocompatible metal, preferably silver, platinum, palladium, gold, manganese, or alloys or oxides thereof that decomposes reactive oxygen species (ROS), such as hydrogen peroxide, and prevents ROS from oxidizing molecules on the surface of or within the device. The protective material, structure, and/or coating thereby prevents ROS from degrading the in vivo functionality of the implantable device.Type: ApplicationFiled: June 15, 2017Publication date: May 31, 2018Applicant: Senseonics, IncorporatedInventors: Arthur E. Colvin, JR., Hui Jiang
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Publication number: 20170202517Abstract: An implantable device with in vivo functionality, where the functionality of the device is negatively affected by ROS typically associated with inflammation reaction as well as chronic foreign body response as a result of tissue injury, is at least partially surrounded by a protective material, structure, and/or a coating that prevents damage to the device from any inflammation reactions. The protective material, structure, and/or coating is a biocompatible metal, preferably silver, platinum, palladium, gold, manganese, or alloys or oxides thereof that decomposes reactive oxygen species (ROS), such as hydrogen peroxide, and prevents ROS from oxidizing molecules on the surface of or within the device. The protective material, structure, and/or coating thereby prevents ROS from degrading the in vivo functionality of the implantable device.Type: ApplicationFiled: February 3, 2017Publication date: July 20, 2017Applicant: Senseonics, IncorporatedInventors: Arthur E. COLVIN, JR., Hui JIANG
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Patent number: 9693714Abstract: The present invention relates to an optical sensor that may be implanted within a living animal (e.g., a human) and may be used to measure the concentration of an analyte in a medium within the animal. The optical sensor may wirelessly receive and may be capable of bi-directional data communication. The optical sensor may include a semiconductor substrate in which various circuit components, one or more photodectors and/or a light source may be fabricated. The circuit components fabricated in the semiconductor substrate may include a comparator, an analog to digital converter, a temperature transducer, a measurement controller, a rectifier and/or a nonvolatile storage medium. The comparator may output a signal indicative of the difference between the outputs of first and second photodetectors. The measurement controller may receive digitized temperature, photodetector and/or comparator measurements and generate measurement information, which may be wirelessly transmitted from the optical sensor.Type: GrantFiled: February 7, 2013Date of Patent: July 4, 2017Assignee: Senseonics, IncorporatedInventors: Andrew DeHennis, Arthur E. Colvin, Jr.
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Patent number: 9681824Abstract: An implantable device with in vivo functionality, where the functionality of the device is negatively affected by ROS typically associated with inflammation reaction as well as chronic foreign body response as a result of tissue injury, is at least partially surrounded by a protective material, structure, and/or a coating that prevents damage to the device from any inflammation reactions. The protective material, structure, and/or coating is a biocompatible metal, preferably silver, platinum, palladium, gold, manganese, or alloys or oxides thereof that decomposes reactive oxygen species (ROS), such as hydrogen peroxide, and prevents ROS from oxidizing molecules on the surface of or within the device. The protective material, structure, and/or coating thereby prevents ROS from degrading the in vivo functionality of the implantable device.Type: GrantFiled: March 15, 2012Date of Patent: June 20, 2017Assignee: Senseonics, IncorporatedInventors: Arthur E. Colvin, Jr., Hui Jiang
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Publication number: 20170150901Abstract: Systems and methods for automatically triggering wireless power and data exchange between an external reader and an implanted sensor. The implanted sensor may measure the strength of an electrodynamic field received wirelessly from the reader and convey field strength data based on the measured strength of the received electrodynamic field to the reader. If the field strength data indicates that the strength of an electrodynamic field received by the sensor is sufficient for the implanted sensor to perform an analyte measurement, the reader may convey an analyte measurement command to the sensor, which may execute the analyte measurement command and convey measurement information back to the reader. The systems and methods may trigger the analyte measurement as the reader transiently passes within sufficient range/proximity to the implant (or vice versa).Type: ApplicationFiled: February 10, 2017Publication date: June 1, 2017Applicant: Senseonics, IncorporatedInventors: Arthur E. Colvin, Jr., Andrew DeHennis
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Publication number: 20170119288Abstract: The present invention relates to an optical sensor that may be implanted within a living animal (e.g., a human) and may be used to measure the concentration of an analyte in a medium within the animal. The optical sensor may wirelessly receive and may be capable of bi-directional data communication. The optical sensor may include a semiconductor substrate in which various circuit components, one or more photodectors and/or a light source may be fabricated. The circuit components fabricated in the semiconductor substrate may include a comparator, an analog to digital converter, a temperature transducer, a measurement controller, a rectifier and/or a nonvolatile storage medium. The comparator may output a signal indicative of the difference between the outputs of first and second photodetectors. The measurement controller may receive digitized temperature, photodetector and/or comparator measurements and generate measurement information, which may be wirelessly transmitted from the optical sensor.Type: ApplicationFiled: January 11, 2017Publication date: May 4, 2017Applicant: Senseonics, IncorporatedInventors: Andrew DeHennis, Arthur E. Colvin, JR.
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Publication number: 20160374556Abstract: Some embodiments described herein relate to a reader having a distributed source of radiation and a photodetector. The photodetector can be operable to sense radiation (e.g., light) emitted by an implanted sensor. The distributed source of radiation can at least partially surrounds the photodetector. The distributed source of radiation generates a photon cloud of excitation radiation within the skin, which can substantially envelopes a sensor that is implanted within the skin at a depth that is on the order of a centimeter or less.Type: ApplicationFiled: June 27, 2016Publication date: December 29, 2016Inventors: Arthur E. COLVIN, JR., William A. MCMILLAN, Steven PULLINS
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Patent number: 9414775Abstract: Methods, sensors, and systems for determining a concentration of glucose in a medium of a living animal are disclosed. Determining the glucose concentration may involve emitting excitation light from a light source to indicator molecules, generating a raw signal indicative of the amount of light received by a photodetector, purifying and normalizing the raw signal, and converting the normalized signal to a glucose concentration. The purification may involve removing noise (e.g., offset and/or distortion) from the raw signal. The purification and normalization may involve tracking the cumulative emission time that the light source has emitted the excitation light and tracking the implant time that has elapsed since the optical sensor was implanted. The purification and normalization may involve measuring the temperature of the sensor. The purification, normalization, and conversion may involve using parameters determined during manufacturing, in vitro testing, and/or in vivo testing.Type: GrantFiled: July 9, 2013Date of Patent: August 16, 2016Assignee: Senseonics, IncorporatedInventors: Arthur E. Colvin, Jr., Xiaolin Wang, Colleen Mdingi, Andrew DeHennis
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Patent number: 9377351Abstract: Apparatuses and methods for limiting the angle of incidence (AOI) of light reaching a dichroic filter. The apparatus may include an AOI filter element and the dichroic filter. The apparatus may be a sensor and may include a photodetector. The dichroic filter may be configured to prevent light having a wavelength outside a band pass region from reaching the photodetector and to pass light having a wavelength within the band pass. Physical limitations of the dichroic filter may preclude the dichroic filter from preventing high AOI light having a wavelength outside a band pass region from reaching the photodetector. The AOI filter element may be configured to prevent light having a high AOI from reaching the dichroic band pass filter and to propagate light having a low AOI to the dichroic band pass filter. The AOI filter element may be a fiber optic bundle comprising a plurality of optical fibers.Type: GrantFiled: April 24, 2013Date of Patent: June 28, 2016Assignee: Senseonics, IncorporatedInventor: Arthur E. Colvin, Jr.
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Patent number: 9345426Abstract: Methods, sensors, and systems for determining a concentration of glucose in a medium of a living animal are disclosed. Determining the glucose concentration may involve emitting excitation light from a light source to indicator molecules, generating a raw signal indicative of the amount of light received by a photodetector, purifying and normalizing the raw signal, and converting the normalized signal to a glucose concentration. The purification may involve removing noise (e.g., offset and/or distortion) from the raw signal. The purification and normalization may involve tracking the cumulative emission time that the light source has emitted the excitation light and tracking the implant time that has elapsed since the optical sensor was implanted. The purification and normalization may involve measuring the temperature of the sensor. The purification, normalization, and conversion may involve using parameters determined during manufacturing, in vitro testing, and/or in vivo testing.Type: GrantFiled: March 29, 2013Date of Patent: May 24, 2016Assignee: Senseonics, IncorporatedInventors: Arthur E. Colvin, Jr., Xiaolin Wang, Colleen Mdingi, Andrew DeHennis
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Publication number: 20150330828Abstract: A fuel-gauge system detects the angular position of a float-based fluid-level-detecting mechanism's magnet and determines the level of liquid fuel remaining within a cylinder. The system wirelessly transmits to an app or application running on a multipurpose, consumer computing device fuel-remaining information, either in terms of percentage of maximum fluid level or, preferably, in terms of actual fluid volume remaining. The system determines fluid temperature and compensates for variation in the fluid-level attributable to temperature fluctuation.Type: ApplicationFiled: May 15, 2015Publication date: November 19, 2015Inventor: Arthur E. Colvin, JR.
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Publication number: 20140088383Abstract: An implantable device with in vivo functionality, where the functionality of the device is negatively affected by ROS typically associated with inflammation reaction as well as chronic foreign body response as a result of tissue injury, is at least partially surrounded by a protective material, structure, and/or a coating that prevents damage to the device from any inflammation reactions. The protective material, structure, and/or coating is a biocompatible metal, preferably silver, platinum, palladium, gold, manganese, or alloys or oxides thereof that decomposes reactive oxygen species (ROS), such as hydrogen peroxide, and prevents ROS from oxidizing molecules on the surface of or within the device. The protective material, structure, and/or coating thereby prevents ROS from degrading the in vivo functionality of the implantable device.Type: ApplicationFiled: September 11, 2013Publication date: March 27, 2014Applicant: Senseonics, IncorporatedInventors: Arthur E. Colvin, JR., Hui Jiang