Patents by Inventor Arunya Usayapant

Arunya Usayapant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220096414
    Abstract: The present invention is directed to a pharmaceutical product which includes a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes a cyclodextrin, water, and an amine, and has a pH above the buffering range of the amine. The liquid formulation of the invention is stable and ready-to-use.
    Type: Application
    Filed: December 14, 2021
    Publication date: March 31, 2022
    Applicant: Fresenius Kabi USA, LLC
    Inventors: Arunya USAYAPANT, Basma M. IBRAHIM
  • Patent number: 11135190
    Abstract: The present invention is directed to a pharmaceutical product which includes a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes tromethamine, sodium iodide, and water and has a pH of about 9.0 to about 11.5. The liquid formulation according to the invention is stable and ready-to-use.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: October 5, 2021
    Assignee: Fresenius Kabi USA, LLC
    Inventors: Arunya Usayapant, Basma M. Ibrahim
  • Publication number: 20210251931
    Abstract: The present invention is directed to a pharmaceutical product which includes a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes a cyclodextrin and water and has a pH of about 9.0 to about 11.5. The liquid formulation according to the invention is stable and ready-to-use.
    Type: Application
    Filed: May 3, 2021
    Publication date: August 19, 2021
    Applicant: Fresenius Kabi USA, LLC
    Inventors: Arunya USAYAPANT, Basma M. IBRAHIM
  • Publication number: 20190336463
    Abstract: The present invention is directed to a pharmaceutical product which includes a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes tromethamine, sodium iodide, and water and has a pH of about 9.0 to about 11.5. The liquid formulation according to the invention is stable and ready-to-use.
    Type: Application
    Filed: July 15, 2019
    Publication date: November 7, 2019
    Applicant: Fresenius Kabi USA, LLC
    Inventors: Arunya USAYAPANT, Basma M. IBRAHIM
  • Patent number: 10398669
    Abstract: The present invention is directed to a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes tromethamine, sodium iodide, and water and has a pH of about 9.0 to about 11.5. The liquid formulation according to the invention is stable and ready-to-use.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: September 3, 2019
    Assignee: Fresenius Kabi USA, LLC
    Inventors: Arunya Usayapant, Basma M. Ibrahim
  • Publication number: 20190105392
    Abstract: A caspofungin composition includes caspofungin acetate and at least one amino acid, where the composition is a solid. The solid composition may be made by forming a liquid mixture including a solvent, caspofungin acetate and the amino acid(s), and lyophilizing the liquid mixture.
    Type: Application
    Filed: April 6, 2018
    Publication date: April 11, 2019
    Applicant: Fresenius Kabi USA LLC
    Inventors: John Jiang, Arunya Usayapant, David Bowman, Keith Kwok, Joel Peterson
  • Publication number: 20180153838
    Abstract: The present invention is directed to a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes tromethamine, sodium iodide, and water and has a pH of about 9.0 to about 11.5. The liquid formulation according to the invention is stable and ready-to-use.
    Type: Application
    Filed: September 11, 2017
    Publication date: June 7, 2018
    Applicant: Fresenius Kabi USA, LLC
    Inventors: Arunya USAYAPANT, Basma M. IBRAHIM
  • Publication number: 20170296667
    Abstract: A caspofungin composition includes caspofungin acetate and at least one amino acid, where the composition is a solid. The solid composition may be made by forming a liquid mixture including a solvent, caspofungin acetate and the amino acid(s), and lyophilizing the liquid mixture.
    Type: Application
    Filed: March 30, 2017
    Publication date: October 19, 2017
    Applicant: Fresenius Kabi USA LLC
    Inventors: John Jiang, Arunya Usayapant, David Bowman, Keith Kwok, Joel Peterson
  • Patent number: 9782376
    Abstract: The present invention is directed to a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes tromethamine, sodium iodide, and water and has a pH of about 9.0 to about 11.5. The liquid formulation according to the invention is stable and ready-to-use.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: October 10, 2017
    Assignee: Fresenius Kabi USA LLC
    Inventors: Arunya Usayapant, Basma M. Ibrahim
  • Patent number: 9636407
    Abstract: A caspofungin composition includes caspofungin acetate and at least one amino acid, where the composition is a solid. The solid composition may be made by forming a liquid mixture including a solvent, caspofungin acetate and the amino acid(s), and lyophilizing the liquid mixture.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: May 2, 2017
    Assignee: FRESENIUS KABI USA, LLC
    Inventors: John Zhiqiang Jiang, Arunya Usayapant, David Bowman, Keith Kwok, Joel Peterson
  • Publication number: 20160310597
    Abstract: A caspofungin composition includes caspofungin acetate and at least one amino acid, where the composition is a solid. The solid composition may be made by forming a liquid mixture including a solvent, caspofungin acetate and the amino acid(s), and lyophilizing the liquid mixture.
    Type: Application
    Filed: May 26, 2016
    Publication date: October 27, 2016
    Inventors: John Jiang, Arunya Usayapant, David Bowman, Keith Kwok, Joel Peterson
  • Publication number: 20160015641
    Abstract: A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a lyophilized solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 0.1 to 7 milligrams mannitol.
    Type: Application
    Filed: September 25, 2015
    Publication date: January 21, 2016
    Applicant: FRESENIUS KABI USA, LLC
    Inventors: John Zhiqiang Jiang, Arunya Usayapant, George Monen
  • Patent number: 9168239
    Abstract: A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a lyophilized solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 2 to 4 milligrams mannitol.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: October 27, 2015
    Assignee: Fresenius Kabi USA, LLC
    Inventors: John Zhiqiang Jiang, Arunya Usayapant, George Monen
  • Patent number: 9168238
    Abstract: A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a lyophilized solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 2 to 4 milligrams mannitol.
    Type: Grant
    Filed: March 8, 2015
    Date of Patent: October 27, 2015
    Assignee: Fresenius Kabi USA, LLC
    Inventors: John Zhiqiang Jiang, Arunya Usayapant, George Monen
  • Publication number: 20150182484
    Abstract: A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a lyophilized solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 2 to 4 milligrams mannitol.
    Type: Application
    Filed: March 13, 2015
    Publication date: July 2, 2015
    Applicant: FRESENIUS KABI USA, LLC
    Inventors: Zhi-Qiang Jiang, Arunya Usayapant, George Monen
  • Publication number: 20150174246
    Abstract: A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a lyophilized solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 2 to 4 milligrams mannitol.
    Type: Application
    Filed: March 8, 2015
    Publication date: June 25, 2015
    Applicant: FRESENIUS KABI USA, LLC
    Inventors: Zhi-Qiang Jiang, Arunya Usayapant, George Monen
  • Patent number: 9006289
    Abstract: A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 1 to 5 milligrams mannitol. The composition may include from 100 to 200 micrograms levothyroxine sodium, and the mass ratio of mannitol to levothyroxine sodium in the composition may be at most 40:1. The composition may include about 500 micrograms levothyroxine sodium, and the mass ratio of mannitol to levothyroxine sodium in the composition may be at most 10:1.
    Type: Grant
    Filed: August 29, 2012
    Date of Patent: April 14, 2015
    Assignee: Fresenius Kabi USA, LLC
    Inventors: Zhi-Qiang Jiang, Arunya Usayapant, George Monen
  • Patent number: 8962572
    Abstract: A bortezomib composition includes bortezomib and boric acid in a mass ratio of boric acid to bortezomib is from 1:1 to 10:1. The composition is a solid, and may be prepared by forming a liquid mixture including a solvent, bortezomib and boric acid, and lyophilizing the liquid mixture.
    Type: Grant
    Filed: October 4, 2011
    Date of Patent: February 24, 2015
    Assignee: Fresenius Kabi USA, LLC
    Inventors: Arunya Usayapant, David Bowman
  • Publication number: 20140142032
    Abstract: A caspofungin composition includes caspofungin acetate and at least one amino acid, where the composition is a solid. The solid composition may be made by forming a liquid mixture including a solvent, caspofungin acetate and the amino acid(s), and lyophilizing the liquid mixture.
    Type: Application
    Filed: December 21, 2012
    Publication date: May 22, 2014
    Inventors: Zhi-Qiang Jiang, Arunya Usayapant, David Bowman, Keith Kwok, Joel Peterson
  • Publication number: 20130053445
    Abstract: A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 1 to 5 milligrams mannitol. The composition may include from 100 to 200 micrograms levothyroxine sodium, and the mass ratio of mannitol to levothyroxine sodium in the composition may be at most 40:1. The composition may include about 500 micrograms levothyroxine sodium, and the mass ratio of mannitol to levothyroxine sodium in the composition may be at most 10:1.
    Type: Application
    Filed: August 29, 2012
    Publication date: February 28, 2013
    Applicant: FRESENIUS KABI USA, LLC
    Inventors: Zhi-Qiang Jiang, Arunya Usayapant, George Monen