Patents by Inventor Arunya Usayapant
Arunya Usayapant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220096414Abstract: The present invention is directed to a pharmaceutical product which includes a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes a cyclodextrin, water, and an amine, and has a pH above the buffering range of the amine. The liquid formulation of the invention is stable and ready-to-use.Type: ApplicationFiled: December 14, 2021Publication date: March 31, 2022Applicant: Fresenius Kabi USA, LLCInventors: Arunya USAYAPANT, Basma M. IBRAHIM
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Patent number: 11135190Abstract: The present invention is directed to a pharmaceutical product which includes a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes tromethamine, sodium iodide, and water and has a pH of about 9.0 to about 11.5. The liquid formulation according to the invention is stable and ready-to-use.Type: GrantFiled: July 15, 2019Date of Patent: October 5, 2021Assignee: Fresenius Kabi USA, LLCInventors: Arunya Usayapant, Basma M. Ibrahim
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Publication number: 20210251931Abstract: The present invention is directed to a pharmaceutical product which includes a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes a cyclodextrin and water and has a pH of about 9.0 to about 11.5. The liquid formulation according to the invention is stable and ready-to-use.Type: ApplicationFiled: May 3, 2021Publication date: August 19, 2021Applicant: Fresenius Kabi USA, LLCInventors: Arunya USAYAPANT, Basma M. IBRAHIM
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Publication number: 20190336463Abstract: The present invention is directed to a pharmaceutical product which includes a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes tromethamine, sodium iodide, and water and has a pH of about 9.0 to about 11.5. The liquid formulation according to the invention is stable and ready-to-use.Type: ApplicationFiled: July 15, 2019Publication date: November 7, 2019Applicant: Fresenius Kabi USA, LLCInventors: Arunya USAYAPANT, Basma M. IBRAHIM
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Patent number: 10398669Abstract: The present invention is directed to a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes tromethamine, sodium iodide, and water and has a pH of about 9.0 to about 11.5. The liquid formulation according to the invention is stable and ready-to-use.Type: GrantFiled: September 11, 2017Date of Patent: September 3, 2019Assignee: Fresenius Kabi USA, LLCInventors: Arunya Usayapant, Basma M. Ibrahim
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Publication number: 20190105392Abstract: A caspofungin composition includes caspofungin acetate and at least one amino acid, where the composition is a solid. The solid composition may be made by forming a liquid mixture including a solvent, caspofungin acetate and the amino acid(s), and lyophilizing the liquid mixture.Type: ApplicationFiled: April 6, 2018Publication date: April 11, 2019Applicant: Fresenius Kabi USA LLCInventors: John Jiang, Arunya Usayapant, David Bowman, Keith Kwok, Joel Peterson
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Publication number: 20180153838Abstract: The present invention is directed to a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes tromethamine, sodium iodide, and water and has a pH of about 9.0 to about 11.5. The liquid formulation according to the invention is stable and ready-to-use.Type: ApplicationFiled: September 11, 2017Publication date: June 7, 2018Applicant: Fresenius Kabi USA, LLCInventors: Arunya USAYAPANT, Basma M. IBRAHIM
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Publication number: 20170296667Abstract: A caspofungin composition includes caspofungin acetate and at least one amino acid, where the composition is a solid. The solid composition may be made by forming a liquid mixture including a solvent, caspofungin acetate and the amino acid(s), and lyophilizing the liquid mixture.Type: ApplicationFiled: March 30, 2017Publication date: October 19, 2017Applicant: Fresenius Kabi USA LLCInventors: John Jiang, Arunya Usayapant, David Bowman, Keith Kwok, Joel Peterson
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Patent number: 9782376Abstract: The present invention is directed to a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes tromethamine, sodium iodide, and water and has a pH of about 9.0 to about 11.5. The liquid formulation according to the invention is stable and ready-to-use.Type: GrantFiled: December 1, 2016Date of Patent: October 10, 2017Assignee: Fresenius Kabi USA LLCInventors: Arunya Usayapant, Basma M. Ibrahim
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Patent number: 9636407Abstract: A caspofungin composition includes caspofungin acetate and at least one amino acid, where the composition is a solid. The solid composition may be made by forming a liquid mixture including a solvent, caspofungin acetate and the amino acid(s), and lyophilizing the liquid mixture.Type: GrantFiled: December 21, 2012Date of Patent: May 2, 2017Assignee: FRESENIUS KABI USA, LLCInventors: John Zhiqiang Jiang, Arunya Usayapant, David Bowman, Keith Kwok, Joel Peterson
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Publication number: 20160310597Abstract: A caspofungin composition includes caspofungin acetate and at least one amino acid, where the composition is a solid. The solid composition may be made by forming a liquid mixture including a solvent, caspofungin acetate and the amino acid(s), and lyophilizing the liquid mixture.Type: ApplicationFiled: May 26, 2016Publication date: October 27, 2016Inventors: John Jiang, Arunya Usayapant, David Bowman, Keith Kwok, Joel Peterson
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Publication number: 20160015641Abstract: A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a lyophilized solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 0.1 to 7 milligrams mannitol.Type: ApplicationFiled: September 25, 2015Publication date: January 21, 2016Applicant: FRESENIUS KABI USA, LLCInventors: John Zhiqiang Jiang, Arunya Usayapant, George Monen
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Patent number: 9168239Abstract: A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a lyophilized solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 2 to 4 milligrams mannitol.Type: GrantFiled: March 13, 2015Date of Patent: October 27, 2015Assignee: Fresenius Kabi USA, LLCInventors: John Zhiqiang Jiang, Arunya Usayapant, George Monen
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Patent number: 9168238Abstract: A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a lyophilized solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 2 to 4 milligrams mannitol.Type: GrantFiled: March 8, 2015Date of Patent: October 27, 2015Assignee: Fresenius Kabi USA, LLCInventors: John Zhiqiang Jiang, Arunya Usayapant, George Monen
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Publication number: 20150182484Abstract: A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a lyophilized solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 2 to 4 milligrams mannitol.Type: ApplicationFiled: March 13, 2015Publication date: July 2, 2015Applicant: FRESENIUS KABI USA, LLCInventors: Zhi-Qiang Jiang, Arunya Usayapant, George Monen
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Publication number: 20150174246Abstract: A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a lyophilized solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 2 to 4 milligrams mannitol.Type: ApplicationFiled: March 8, 2015Publication date: June 25, 2015Applicant: FRESENIUS KABI USA, LLCInventors: Zhi-Qiang Jiang, Arunya Usayapant, George Monen
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Patent number: 9006289Abstract: A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 1 to 5 milligrams mannitol. The composition may include from 100 to 200 micrograms levothyroxine sodium, and the mass ratio of mannitol to levothyroxine sodium in the composition may be at most 40:1. The composition may include about 500 micrograms levothyroxine sodium, and the mass ratio of mannitol to levothyroxine sodium in the composition may be at most 10:1.Type: GrantFiled: August 29, 2012Date of Patent: April 14, 2015Assignee: Fresenius Kabi USA, LLCInventors: Zhi-Qiang Jiang, Arunya Usayapant, George Monen
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Patent number: 8962572Abstract: A bortezomib composition includes bortezomib and boric acid in a mass ratio of boric acid to bortezomib is from 1:1 to 10:1. The composition is a solid, and may be prepared by forming a liquid mixture including a solvent, bortezomib and boric acid, and lyophilizing the liquid mixture.Type: GrantFiled: October 4, 2011Date of Patent: February 24, 2015Assignee: Fresenius Kabi USA, LLCInventors: Arunya Usayapant, David Bowman
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Publication number: 20140142032Abstract: A caspofungin composition includes caspofungin acetate and at least one amino acid, where the composition is a solid. The solid composition may be made by forming a liquid mixture including a solvent, caspofungin acetate and the amino acid(s), and lyophilizing the liquid mixture.Type: ApplicationFiled: December 21, 2012Publication date: May 22, 2014Inventors: Zhi-Qiang Jiang, Arunya Usayapant, David Bowman, Keith Kwok, Joel Peterson
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Publication number: 20130053445Abstract: A levothyroxine composition includes levothyroxine sodium and mannitol. The composition is a solid. The composition may include from 100 to 500 micrograms levothyroxine sodium and from 1 to 5 milligrams mannitol. The composition may include from 100 to 200 micrograms levothyroxine sodium, and the mass ratio of mannitol to levothyroxine sodium in the composition may be at most 40:1. The composition may include about 500 micrograms levothyroxine sodium, and the mass ratio of mannitol to levothyroxine sodium in the composition may be at most 10:1.Type: ApplicationFiled: August 29, 2012Publication date: February 28, 2013Applicant: FRESENIUS KABI USA, LLCInventors: Zhi-Qiang Jiang, Arunya Usayapant, George Monen