Patents by Inventor Arvind Devshi Varsani

Arvind Devshi Varsani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimaeric human papillomavirus 16 L1 virus-like particles and a method for preparing the particles
    Patent number: 8163557
    Abstract: A method for producing a chimaeric human papillomavirus (HPV) L1 polypeptide containing a heterologous peptide, and in particular, a HPV L2 peptide comprising the steps of introducing a DNA sequence coding for the heterologous peptide into a DNA sequence coding for the L1 polypeptide; introducing the DNA sequence including the sequences for the L1 polypeptide and heterologous peptide into a host cell in which the DNA sequence can be expressed; causing expression of the DNA sequence; and recovering the resulting chimaeric L1 polypeptide which includes the heterologous peptide. The invention also describes a vector for use in the method, a host cell containing the vector, and a vaccine including the chimaeric HPV L1 polypeptide produced according to the method.
    Type: Grant
    Filed: July 16, 2008
    Date of Patent: April 24, 2012
    Assignee: University of Cape Town
    Inventors: Arvind Devshi Varsani, Edward Peter Rybicki
  • Chimaeric Human Papillomavirus 16 L1 Virus Like Particles and a Method for Preparing the Particles
    Publication number: 20090047302
    Abstract: A method for producing a chimaeric human papillomavirus (HPV) L1 polypeptide containing a heterologous peptide, and in particular, a HPV L2 peptide comprising the steps of introducing a DNA sequence coding for the heterologous peptide into a DNA sequence coding for the L1 polypeptide; introducing the DNA sequence including the sequences for the L1 polypeptide and heterologous peptide into a host cell in which the DNA sequence can be expressed; causing expression of the DNA sequence; and recovering the resulting chimaeric L1 polypeptide which includes the heterologous peptide. The invention also describes a vector for use in the method, a host cell containing the vector, and a vaccine including the chimaeric HPV L1 polypeptide produced according to the method.
    Type: Application
    Filed: July 16, 2008
    Publication date: February 19, 2009
    Applicant: UNIVERSITY OF CAPE TOWN
    Inventors: Arvind Devshi Varsani, Edward Peter Rybicki
  • Chimaeric human papillomavirus 16 I1 virus like particles and a method for preparing the particles
    Patent number: 7407807
    Abstract: The invention describes a method for producing a chimaeric human papillomavirus (HPV) L1 polypeptide containing a heterologous peptide, and in particular, a HPV L2 peptide. The method comprises the steps of introducing a DNA sequence coding for the heterologous peptide into a DNA sequence coding for the L1 polypeptide; introducing the DNA sequence including the sequences for the L1 polypeptide and heterologous peptide into a host cell in which the DNA sequence can be expressed; causing expression of the DNA sequence; and recovering the resulting chimaeric L1 polypeptide which includes the heterologous peptide. Typically, the nucleotides encoding the heterologous peptide replace the nucleotides of the L1 polypeptide at the point of insertion. The invention also describes a vector for use in the method, a host cell containing the vector, and a vaccine including the chimaeric HPV L1 polypeptide produced according to the method.
    Type: Grant
    Filed: May 19, 2003
    Date of Patent: August 5, 2008
    Assignee: University of Cape Town
    Inventors: Arvind Devshi Varsani, Edward Peter Rybicki