Abstract: An embodiment may have two rotary discs including a second disc (a cap) and a first disc; and a rotary ‘cam’ (having ports) placed in the central hole of the first disc. A cap is half the diameter of the first disc. Both face each other and maintain contour complementarity during both of two modes of operation The cap seals the cavity underneath, and without jeopardizing the sealing, permits entry and exit of the radial ridges and furrows of the first disc into it. The ridges sweep the floor (under surface) of the cap and divide the cavity into variable volume compartments that suck and expel fluid simultaneously through the ‘cam’. The machine is designed to work as rotary pump, compressor, turbine or internal combustion engine.

Abstract: An embodiment may have two rotary discs including a second disc (a cap) and a first disc; and a rotary ‘cam’ (having ports) placed in the central hole of the first disc. A cap is half the diameter of the first disc. Both face each other and maintain contour complementarity (wall height of the second disc+radial depth of the first disc is constant at contact); either, when both discs rotate on their axes, placed the second disc's radius apart, or when the second disc rotates and revolves on the face of stationary first disc. The cap seals the cavity underneath during the two motions, and without jeopardizing the sealing, permits entry and exit of the radial ridges and furrows of the first disc into it. The ridges sweep the floor (under surface) of the cap and divide the cavity into variable volume compartments that suck and expel fluid simultaneously through the ‘cam’. The machine is designed to work as rotary pump, compressor, turbine or internal combustion engine.

Abstract: The invention provides novel paclitaxel derivatives obtained by effecting modifications at C2′, C3′ and/or C7 positions of paclitaxel, said derivatives being useful in inhibiting the growth of cancer of lung, breast, ovary, cervix or leukemia, and pharmaceutical compositions comprising such derivatives.