Patents by Inventor Arvind L. Thakkar

Arvind L. Thakkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Solid orally administerable raloxifene hydrochloride pharmaceutical formulation
    Patent number: 5972383
    Abstract: This invention provides orally administerable pharmaceutical formulations comprising raloxifene, its ethers or esters, or a pharmaceutically-acceptable salt thereof, in combination with a hydrophilic carrier composition.
    Type: Grant
    Filed: June 1, 1998
    Date of Patent: October 26, 1999
    Assignee: Eli Lilly and Company
    Inventors: Lowell L. Gibson, Kerry J. Hartauer, Julian L. Stowers, Stephanie A. Sweetana, Arvind L. Thakkar
  • Solid orally administerable raloxifene hydrochloride pharmaceutical formulation
    Patent number: 5811120
    Abstract: This invention provides solid orally administerable pharmaceutical formulations comprising raloxifene hydrochloride, a surfactant being sorbitan fatty acid ester or a polyoxyethylene sorbitan fatty acid ester, polyvinylpyrrolidone, and a water soluble diluent which is polyol or sugar.
    Type: Grant
    Filed: March 26, 1997
    Date of Patent: September 22, 1998
    Assignee: Eli Lilly and Company
    Inventors: Lowell L. Gibson, Kerry J. Hartauer, Julian L. Stowers, Stephanie A. Sweetana, Arvind L. Thakkar
  • Aqueous solution inclusion complexes of benzothiophene compounds with water soluble cyclodextrins, and pharmaceutical formulations and methods thereof
    Patent number: 5624940
    Abstract: The present invention provides aqueous inclusion complexes of certain known benzothiophene compounds, particularly Raloxifene, and water soluble cyclodextrins. Also provided are pharmaceutical compositions of such inclusion complexes, and methods of using these complexes for inhibiting bone loss and reducing serum cholesterol in mammals.
    Type: Grant
    Filed: June 30, 1995
    Date of Patent: April 29, 1997
    Assignee: Eli Lilly and Company
    Inventors: Henry U. Bryant, George J. Cullinan, Paul C. Francis, David E. Magee, Stephanie A. Sweetana, Arvind L. Thakkar
  • Orally administerable sustained release pharmaceutical formulation
    Patent number: 5112619
    Abstract: This invention provides orally administerable pharmaceutical formulations having a semi-solid matrix containing a hydrophilic substance capable of creating channels in a hydrophobic carrier matrix thereby providing a sustained rate of release of an active agent from the formulation.
    Type: Grant
    Filed: September 14, 1989
    Date of Patent: May 12, 1992
    Assignee: Eli Lilly and Company
    Inventors: Arvind L. Thakkar, Lowell L. Gibson
  • Orally administerable sustained release pharmaceutical formulations
    Patent number: 4847092
    Abstract: This invention provides orally administerable pharmaceutical formulations having a semi-solid matrix containing a hydrophilic substance capable of creating channels in a hydrophobic carrier matrix thereby providing a sustained rate of release of an active agent from the formulation.
    Type: Grant
    Filed: August 19, 1988
    Date of Patent: July 11, 1989
    Assignee: Eli Lilly and Company
    Inventors: Arvind L. Thakkar, Lowell L. Gibson
  • Orally administerable sustained release pharmaceutical formulations
    Patent number: 4797286
    Abstract: This invention provides orally administerable pharmaceutical formulations having a semi-solid matrix containing a hydrophilic substance capable of creating channels in a hydrophobic carrier matrix thereby providing a sustained rate of release of an active agent from the formulation.
    Type: Grant
    Filed: November 12, 1985
    Date of Patent: January 10, 1989
    Assignee: Eli Lilly and Company
    Inventors: Arvind L. Thakkar, Lowell L. Gibson
  • Injectable semi-solid formulations
    Patent number: 4775659
    Abstract: This invention provides injectable semi-solid formulations comprising a pharmaceutically or veterinary active agent, an oil and a suitable glyceride release modifying agent.
    Type: Grant
    Filed: August 19, 1985
    Date of Patent: October 4, 1988
    Assignee: Eli Lilly and Company
    Inventors: Arvind L. Thakkar, Roger G. Harrison
  • Contraceptive methods
    Patent number: 4493699
    Abstract: Long chain alkyl and alkenyl sulfonates, sulfates and sulfoalkyl alkanoate salts, administered intravaginally for contraception.
    Type: Grant
    Filed: April 8, 1982
    Date of Patent: January 15, 1985
    Assignee: Eli Lilly and Company
    Inventors: Ronald E. Zimmerman, Philip J. Burck, C. David Jones, Arvind L. Thakkar
  • Novel polymorphic crystalline form of dibenzopyranone
    Patent number: 4278603
    Abstract: Stable polymorphic crystalline form of trans-dl-1-hydroxy-3-(1',1'-dimethylheptyl)-6,6-dimethyl-6,6a,7,8,-10,10a- hexahydro-9H-dibenzo[b,d]pyran-9-one, capable of producing significant blood levels in mammals for long periods of time after oral administration of the drug.
    Type: Grant
    Filed: August 8, 1977
    Date of Patent: July 14, 1981
    Assignee: Eli Lilly and Company
    Inventor: Arvind L. Thakkar
  • Contraceptive methods and compositions
    Patent number: 4264576
    Abstract: Introduction of a pharmaceutically acceptable non-toxic cation salt of a sulfoalkyl alkanoate, for example, sodium sulfopropyl dodecanoate, into the uterine lumen or vaginal cavity prevents conception.
    Type: Grant
    Filed: April 8, 1980
    Date of Patent: April 28, 1981
    Assignee: Eli Lilly and Company
    Inventors: Ronald E. Zimmerman, Philip J. Burck, C. David Jones, Arvind L. Thakkar
  • Contraceptive methods and compositions
    Patent number: 4264575
    Abstract: Introduction of a pharmaceutically acceptable non-toxic cation salt of a straight-chain or branched chain alkyl sulfonate having from 11 to 16 carbon atoms into the uterine lumen or vaginal cavity prevents conception. Sodium tetradecyl sulfonate is preferred.
    Type: Grant
    Filed: April 8, 1980
    Date of Patent: April 28, 1981
    Assignee: Eli Lilly and Company
    Inventors: Ronald E. Zimmerman, Philip J. Burck, C. David Jones, Arvind L. Thakkar
  • Contraceptive methods and compositions
    Patent number: 4264578
    Abstract: Introduction of a pharmaceutically acceptable non-toxic cation salt of a sterol sulfate into the uterine lumen or vaginal cavity prevents conception. Potassium or pyridinium .beta.-sitosteryl sulfate is preferred.
    Type: Grant
    Filed: April 8, 1980
    Date of Patent: April 28, 1981
    Assignee: Eli Lilly and Company
    Inventors: Philip J. Burck, Ronald E. Zimmerman, Arvind L. Thakkar
  • Contraceptive methods and compositions
    Patent number: 4264577
    Abstract: Introduction of a compound of the formula:R--OSO.sub.3 --Mwherein R is:(a) C.sub.11 -C.sub.30 straight chain alkyl or alkenyl;(b) C.sub.10 -C.sub.30 branched chain alkyl or alkenyl, the .alpha.-carbon of which is not branched; or(c) C.sub.13 -C.sub.30 branched chain alkyl or alkenyl, the .alpha.-carbon of which is branched,and M is a pharmaceutically acceptable non-toxic cation; into the uterine lumen or vaginal cavity prevents conception. Sodium n-tetradecyl sulfate is preferred.
    Type: Grant
    Filed: April 8, 1980
    Date of Patent: April 28, 1981
    Assignee: Eli Lilly and Company
    Inventors: Ronald E. Zimmerman, Philip J. Burck, C. David Jones, Arvind L. Thakkar
  • Antibiotic A-32390 compositions
    Patent number: 4024240
    Abstract: Novel A-32390:PVP compositions useful in the treatment of fungal infections.
    Type: Grant
    Filed: July 18, 1975
    Date of Patent: May 17, 1977
    Assignee: Eli Lilly and Company
    Inventor: Arvind L. Thakkar
  • Dibenzo[b,d]pyranone dispersions
    Patent number: 3988439
    Abstract: 1-Hydroxy-3-alkyl-9-keto or 9-hydroxyhexahydro dibenzo[b,d]pyrans, useful as tranquilizers or hypotensive agents are dispersed with PVP or polyethylene glycol.
    Type: Grant
    Filed: June 23, 1975
    Date of Patent: October 26, 1976
    Assignee: Eli Lilly and Company
    Inventor: Arvind L. Thakkar