Patents by Inventor Arye Rubinstein

Arye Rubinstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110123600
    Abstract: Methods of treating acne are provided. The methods involve applying to the acne an alkyl urea in a pharmaceutically acceptable carrier. The use of an alkyl urea in the manufacture of a medicament for the treatment of acne is also provided. Compositions of alkyl ureas in a pharmaceutically acceptable carrier are additionally provided.
    Type: Application
    Filed: November 5, 2010
    Publication date: May 26, 2011
    Inventor: Arye Rubinstein
  • Publication number: 20050272819
    Abstract: Methods of treating acne are provided. The methods involve applying to the acne an alkyl urea in a pharmaceutically acceptable carrier. The use of an alkyl urea in the manufacture of a medicament for the treatment of acne is also provided. Compositions of alkyl ureas in a pharmaceutically acceptable carrier are additionally provided.
    Type: Application
    Filed: February 2, 2005
    Publication date: December 8, 2005
    Inventor: Arye Rubinstein
  • Publication number: 20030194411
    Abstract: The present invention provides for peptide conjugate compositions, methods of using the peptide conjugate compositions, and pharmaceutical compositions comprising the peptide conjugate compositions. The peptide conjugate compositions comprise peptides with amino acid sequences similar to the gp 120 principal neutralizing domain (PND) of HIV, gp41, and Nef (p27) of HIV and carriers which enhance immunogenicity. The peptide conjugate compositions of the present invention may comprise a multivalent cocktail of several different peptide conjugates. Also provided by present invention is a method for reducing the level of HIV titers in a mammal by administering to the mammal a peptide composition of the present invention in an amount effective to reduce the level of HIV titers. The peptide conjugate compositions of the present invention induce prolonged antibody response in serum, a high level of antibody in the mucosa, and the production of cytotoxic lymphocytes.
    Type: Application
    Filed: August 6, 2002
    Publication date: October 16, 2003
    Inventors: Arye Rubinstein, Barry R. Bloom, Yair Devash, Stanley J. Cryz
  • Patent number: 6447778
    Abstract: The present invention provides for peptide conjugate compositions, methods of using the peptide conjugate compositions, and pharmaceutical compositions comprising the peptide conjugate compositions. The peptide conjugate compositions comprise peptides with amino acid sequences similar to the gp120 principal neutralizing domain (PND) of HIV, gp41, and Nef (p27) of HIV and carriers which enhance immunogenicity. The peptide conjugate compositions of the present invention may comprise a multivalent cocktail of several different peptide conjugates. Also provided by present invention is a method for reducing the level of HIV titers in a mammal by administering to the mammal a peptide composition of the present invention in an amount effective to reduce the level of HIV titers. The peptide conjugate compositions of the present invention induce prolonged antibody response in serum, a high level of antibody in the mucosa, and the production of cytotoxic lymphocytes.
    Type: Grant
    Filed: June 22, 2000
    Date of Patent: September 10, 2002
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Arye Rubinstein, Barry R. Bloom, Yair Devash, Stanley J. Cryz
  • Patent number: 6139843
    Abstract: The present invention provides for peptide conjugate compositions, methods of using the peptide conjugate compositions, and pharmaceutical compositions comprising the peptide conjugate compositions. The peptide conjugate compositions comprise peptides with amino acid sequences similar to the gp120 principal neutralizing domain (PND) of HIV, gp41, and Nef (p27) of HIV and carriers which enhance immunogenicity. The peptide conjugate compositions of the present invention may comprise a multivalent cocktail of several different peptide conjugates. Also provided by present invention is a method for reducing the level of HIV titers in a mammal by administering to the mammal a peptide composition of the present invention in an amount effective to reduce the level of HIV titers. The peptide conjugate compositions of the present invention induce prolonged antibody response in serum, a high level of antibody in the mucosa, and the production of cytotoxic lymphocytes.
    Type: Grant
    Filed: October 7, 1997
    Date of Patent: October 31, 2000
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Arye Rubinstein, Barry R. Bloom, Yair Devash, Stanley J. Cryz
  • Patent number: 5387611
    Abstract: This invention relates to methods of abrogating sperm motility utilizing the anti-bacterial, anti-viral agents butylurea, Nonoxynol-9 and benzalkonium chloride. This invention is further directed to anti-bacterial, anti-viral, non-irritating contraceptive compositions, and to methods of enhancing contraceptive capabilities of conventional contraceptive means as well as to enhanced conventional contraceptive means.
    Type: Grant
    Filed: June 3, 1993
    Date of Patent: February 7, 1995
    Assignee: Albert Einstein College of Medicine of Yeshiva University, a Division of Yeshiva University
    Inventor: Arye Rubinstein
  • Patent number: 5300059
    Abstract: The interior surface of a container, such as a bloodbag, is primed and subsequently coated with a time-releasable viricide against HIV absorbed in a hydrogel polymer. The viricides of this invention are derivatives of urea, and upon release into the blood, have no adverse effects on the red blood cell functions of the blood.
    Type: Grant
    Filed: November 19, 1991
    Date of Patent: April 5, 1994
    Assignees: Hydro Slip Technologies Inc., Albert Einstein College of Medicine
    Inventors: Arye Rubinstein, Albert Goldstein, Howard I. Podell
  • Patent number: 5229423
    Abstract: This invention relates to the use of butylurea as a contraceptive agent. Butylurea may be used either alone or with a pharmaceutically acceptable carrier, and may be used in conjunction with conventional contraceptive means to abrogate sperm motility.
    Type: Grant
    Filed: March 6, 1992
    Date of Patent: July 20, 1993
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventor: Arye Rubinstein